182410-00-0
182410-00-0 結(jié)構(gòu)式
基本信息
磺丁基-B-環(huán)糊精
磺丁基倍他環(huán)糊精鈉
磺丁基醚倍他環(huán)糊精鈉
磺丁基-Β-環(huán)糊精鈉
磺丁基-Β-環(huán)糊精鈉鹽
磺丁基醚倍他環(huán)糊精鈉鹽
B-環(huán)糊精磺丁基醚鈉鹽
磺丁基醚-Β-環(huán)糊精鈉鹽
磺丁基-BETA-環(huán)糊精鈉鹽
CAPTISOL
SBE-β-CD
sodiuM salts
SBE-(beta)-CD
sulfobutyl ethers
sulfobutyl ether B-cyclodextrin
Betadex Sulfobutyl Ether SodiuM
Sulfobutyl -β- cyclodextrin sodium
Sodium sulfobutylether β-cyclodextrin
物理化學(xué)性質(zhì)
SOLVENT
SURFACTANT - CLEANSING
ABSORBENT
安全數(shù)據(jù)
常見問題列表
磺丁基醚-β-環(huán)糊精鈉，是一種新型藥物制劑輔料，屬于陰離子型高水溶性環(huán)糊精的一種磺酸基衍生物。它能很好地與藥物分子包合形成非共價(jià)復(fù)合物，提高了藥物的穩(wěn)定性、水溶性、安全性并且有效的提高了藥物分子的生物活性它的腎毒性小，能緩和藥物溶血性，控制藥物釋放速率。
以β-環(huán)糊精和1,4-磺丁內(nèi)酯為原料，通過向堿性水溶液中引入適量有機(jī)溶劑，增加了1,4-磺丁內(nèi)酯的溶解度，提高了磺丁基醚-β-環(huán)糊精的合成收率；所得產(chǎn)品溶液經(jīng)過超聲透析，活性炭脫色，冷凍干燥等操作得到磺丁基醚-β-環(huán)糊精粉末產(chǎn)品。
SBE-β-CD is a chemically modified β-CD that is a cyclic hydrophilic oligosaccharide which is negatively charged in aqueous media. β-CD functioned is a solubilizer only at low concentrations, whereas SBE7-β-CD exhibits strong solubilizing effects over a wide concentration range.
20% SBE-β-CD in saline:
Guidelines (Following is our recommended protocol. This protocol only provides a guideline, and should be modified according to your specific needs).
1. Dissolve 0.9 g of NaCl in 100 mL distilled water to make a clear 0.9% saline solution.
2. Measure 2 g of dry SBE-β-CD.
3. Dissolve 2 g of SBE-β-CD in 0.9% saline to make 10 mL with a 20% (w/v) concentration. These may require ultrasonic (20-40 kHz, 30 seconds, repeat 3 times) or heating (37°C for about 30 minutes). If precipitation is observed, the precipitates can be dissolved by heating to 37°C and vortexing before use.
| 報(bào)價(jià)日期 | 產(chǎn)品編號(hào) | 產(chǎn)品名稱 | CAS號(hào) | 包裝 | 價(jià)格 |
| 2026/07/06 | 46336 | 磺丁基-β-環(huán)糊精鈉鹽 Sodium sulfobutyl ether beta-cyclodextrin, Thermo Scientific Chemicals | 182410-00-0 | 25g | 941元 |
| 2026/07/06 | S4592 | 磺丁基-Β-環(huán)糊精 Captisol (SBE-β-CD) | 182410-00-0 | 100mg | 291元 |
| 2026/07/06 | S4592 | 磺丁基-Β-環(huán)糊精 Captisol (SBE-β-CD) | 182410-00-0 | 500mg | 351元 |