186689-07-6
中文名稱
2-(N-7-硝基-2,1,3-苯并惡二唑-4-氨基)-2-脫氧-D-葡萄糖
英文名稱
2-(N-(7-NITROBENZ-2-OXA-1,3-DIAZOL-4-YL)AMINO)-2-DEOXYGLUCOSE
CAS
186689-07-6
分子式
C12H14N4O8
分子量
342.26
MOL 文件
186689-07-6.mol
更新日期
2026/06/05 17:25:50
186689-07-6 結(jié)構(gòu)式
基本信息
中文別名
葡萄糖攝取熒光探針葡萄糖轉(zhuǎn)運/血糖通道熒光探針2-NBDG
2-(N-7-硝基-2,1,3-苯并噁二唑-4-氨基)-2-脫氧-D-葡萄糖
2-(N-7-硝基-2,1,3-苯并惡二唑-4-氨基)-2-脫氧-D-葡萄糖
2-脫氧-2-[(7-硝基-2,1,3-苯并惡二唑-4-基)氨基]-D-葡萄糖
2-(N-7-硝基-2,1,3-苯并噁二唑-4-氨基)-2-脫氧-D-葡萄糖, 混合物
英文別名
2-NBDGNBD-GLUCOSE
2-NBD-Glucose
2-NBDG min. 95%
2-Deoxy-2-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]-D-glucose
2-(N-(7-NITROBENZ-2-OXA-1,3-DIAZOL-4-YL)AMINO)-2-DEOXYGLUCOSE
D-Glucose, 2-deoxy-2-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]-
2-NBDG,2-(N-(7-Nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose
2-Deoxy-2-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]-D-glucose >=97% (HPLC)
2-Deoxy-2-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]-D-glucose, 90%, mixed Isomers
所屬類別
生物化工：生化試劑物理化學性質(zhì)
熔點137 - 140°C
沸點740.0±70.0 °C(Predicted)
密度1.750±0.06 g/cm3(Predicted)
儲存條件Inert atmosphere,Store in freezer, under -20°C
溶解度溶于DMSO（高達10mg/ml）。
酸度系數(shù)(pKa)12.96±0.20(Predicted)
形態(tài)固體
顏色深黃色至橙色/紅色
生物來源synthetic
BRN7603370
穩(wěn)定性可在-20°下的DMSO中的溶液儲存長達1個月。
InChIInChI=1S/C12H14N4O8/c17-3-6(11(20)12(21)8(19)4-18)13-5-1-2-7(16(22)23)10-9(5)14-24-15-10/h1-3,6,8,11-13,18-21H,4H2/t6-,8+,11+,12+/m0/s1
InChIKeyQUTFFEUUGHUPQC-ILWYWAAHSA-N
SMILESO=C[C@H](NC1C2C(C([N+]([O-])=O)=CC=1)=NON=2)[C@H]([C@@H]([C@@H](CO)O)O)O
2-(N-7-硝基-2,1,3-苯并惡二唑-4-氨基)-2-脫氧-D-葡萄糖價格(試劑級)
| 報價日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS號 | 包裝 | 價格 |
| 2026/06/05 | HY-116215 | 2-(N-7-硝基-2,1,3-苯并惡二唑-4-氨基)-2-脫氧-D-葡萄糖 2-NBDG | 186689-07-6 | 1 mg | 1047元 |
| 2026/06/05 | HY-116215 | 2-(N-7-硝基-2,1,3-苯并惡二唑-4-氨基)-2-脫氧-D-葡萄糖 2-NBDG | 186689-07-6 | 5mg | 3000元 |
| 2026/06/05 | HY-116215 | 2-(N-7-硝基-2,1,3-苯并惡二唑-4-氨基)-2-脫氧-D-葡萄糖 2-NBDG | 186689-07-6 | 10 mM * 1 mL in DMSO | 3300元 |
常見問題列表
生物活性
2-NBDG，一種熒光脫氧葡萄糖衍生物，是檢測葡萄糖攝取的標志物，也用于檢測細胞活力。體外研究
It has since been demonstrated in living mammalian cells that the uptake of 2-NBDG takes place through glucose transporters (GLUTs) in a concentration-, time- and temperature-dependent manner. A short-period application of 2-NBDG produced a remarkable increase in the fluorescence intensity in COS-1 cells over-expressing GLUT2, whereas the increase was barely detectable in mock-transfected cells. In mouse insulin-secreting clonal MIN6 cells, uptake was inhibited by cytochalasin B, a specific blocker for GLUTs, and by D-glucose in a dose-dependent manner.