219944-46-4
中文名稱
異七葉皂苷 IB
英文名稱
Isoescin IB
CAS
219944-46-4
分子式
C55H86O24
分子量
1131.26
MOL 文件
219944-46-4.mol
更新日期
2025/05/04 20:09:01
219944-46-4 結(jié)構(gòu)式
基本信息
中文別名
異七葉皂苷 IB異七葉樹(shù)皂苷IB
七葉皂苷D(異七葉皂苷IB)
英文別名
Aescin DEscin IVb
Isoescin Ib
Isoescin IB(Isoaescin IB)
Escin Impurity 4（Isoescin IB）
β-D-Glucopyranosiduronic acid, (3β,4β,16α,21β,22α)-28-(acetyloxy)-16,22,23-trihydroxy-21-[[(2Z)-2-methyl-1-oxo-2-buten-1-yl]oxy]olean-12-en-3-yl O-β-D-glucopyranosyl-(1→2)-O-[β-D-glucopyranosyl-(1→4)]-
(3beta,4beta,16alpha,21beta,22alpha)-28-(Acetyloxy)-16,22,23-trihydroxy-21-[[(2Z)-2-methyl-1-oxo-2-buten-1-yl]oxy]olean-12-en-3-yl O-beta-D-glucopyranosyl-(1-2)-O-[beta-D-glucopyranosyl-(1-4)]-beta-D-glucopyranosiduronic acid
所屬類別
生物化工：植物提取物物理化學(xué)性質(zhì)
沸點(diǎn)1148.1±65.0 °C(Predicted)
密度1.46
儲(chǔ)存條件-20°C
溶解度Soluble in methanol;
酸度系數(shù)(pKa)2.63±0.70(Predicted)
形態(tài)powder
顏色White
水溶解性slightly soluble in water
主要應(yīng)用food and beverages
InChIKeyYOSIWGSGLDDTHJ-OXPBSUTMSA-N
安全數(shù)據(jù)
警示詞警告
危險(xiǎn)性描述H302+H332
防范說(shuō)明P301+P312+P330-P304+P340+P312
WGK GermanyWGK 3
存儲(chǔ)類別11 - Combustible Solids
危險(xiǎn)性類別Acute Tox. 4 Inhalation
Acute Tox. 4 Oral
Acute Tox. 4 Oral
異七葉皂苷 IB價(jià)格(試劑級(jí))
| 報(bào)價(jià)日期 | 產(chǎn)品編號(hào) | 產(chǎn)品名稱 | CAS號(hào) | 包裝 | 價(jià)格 |
| 2025/12/22 | HY-N0557 | 異七葉皂苷 IB Isoescin IB | 219944-46-4 | 1 mg | 660元 |
| 2025/12/22 | HY-N0557 | 異七葉皂苷 IB Isoescin IB | 219944-46-4 | 5mg | 1650元 |
| 2025/12/22 | HY-N0557 | 異七葉皂苷 IB Isoescin IB | 219944-46-4 | 10 mg | 2640元 |
常見(jiàn)問(wèn)題列表
生物活性
Isoescin IB 是從七葉樹(shù)種子中分離出來(lái)的，Isoescin IB 是 Escin IB 的異構(gòu)體。Isoescin IB 和 Escin IB 是 Escin 中的主要活性成分。體外研究
β-Escin (mainly consisting of escin Ia and escin Ib) is the major active ingredient in horse chestnut seeds extracts. β-escin can inhibit proliferation and/or induce apoptosis in various types of cancer cells including A549 cell, HT-29 cell, HCC cell, OVCAR3 cell and H-Ras 5RP7 cell. β-escin may be useful as a chemopreventive agent, especially for tumors associated with an inflammatory response.
As the minor component of escin, α-escin (mainly consisting of isoescin Ia and isoescin Ib) exhibits lower bioactivity.