3652-89-9
3652-89-9 結(jié)構(gòu)式
基本信息
4-溴-9H-咔唑
4-溴咔唑 10G
4-broMocarbazole
Carbazole, 4-bromo-
4-bromo-1H-carbazole
4-Bromocarbazole >
4-BroMo-9H-carbazole
9H-Carbazole, 4-broMo-
4-BroMo-9H-carbazole (4BC)
1-CYCLOPROPYL-2,6-PIPERAZINEDIONE
4-BroMo-9H-carbazole ISO 9001：2015 REACH
物理化學(xué)性質(zhì)
制備方法
17613-47-7
3652-89-9
以2-溴-2'-硝基-1,1'-聯(lián)苯為原料合成4-溴-9H-咔唑的一般步驟：將2-溴-2'-硝基-1,1'-聯(lián)苯（4.7 g，16.9 mmol）和三苯基膦（11.08 g，42.25 mmol）溶解于1,2-二氯苯（110 mL）中。將反應(yīng)混合物加熱回流12小時，隨后冷卻至室溫。反應(yīng)液用二氯甲烷和水進(jìn)行萃取，合并有機(jī)層并用無水硫酸鎂干燥。減壓濃縮后，通過柱色譜法（洗脫劑：二氯甲烷/正己烷，1:9，v/v）純化，得到白色粉末狀產(chǎn)物4-溴-9H-咔唑3.6 g，產(chǎn)率87%。產(chǎn)物表征數(shù)據(jù)如下：1H NMR (200 MHz, CDCl3) δ 8.75 (d, 1H, J = 8.0 Hz), 8.18 (s, 1H), 7.49-7.22 (m, 6H); MS (FAB) m/z 247 [(M + H)+]。
參考文獻(xiàn)：
[1] Organic Electronics: physics, materials, applications, 2013, vol. 14, # 1, p. 67 - 73
[2] Patent: WO2017/196081, 2017, A1. Location in patent: Paragraph 281; 282; 283; 284
[3] Patent: KR2016/6007, 2016, A. Location in patent: Paragraph 0439-0441
[4] Patent: KR2016/20159, 2016, A. Location in patent: Paragraph 0356-0359
[5] Patent: KR2015/133097, 2015, A. Location in patent: Paragraph 0282; 0283