52205-73-9
52205-73-9 結(jié)構(gòu)式
基本信息
ESTRAMUSTINE PHOSPHATE SODIUM
-(dihydrogenphosphate),disodiumsalt
3,5(10)-triene-3,17-diol(17-beta)-estra-3-(bis(2-chloroethyl)carbamate)17
emcyt
estra-1,3,5(10)-triene-3,17-beta-diol3-(bis(2-chloroethyl)carbamate)17-disod
estracytsodium
estramustinephosphatedisodium
iumphosphate
Estra-1,3,5(10)-triene-3,17-diol (17beta)-, 3-[bis(2-chloroethyl)carbamate] 17-(dihydrogen phosphate), disodium salt
Estra-1,3,5(10)-triene-3,17-diol (17β)-, 3-[bis(2-chloroethyl)carbamate] 17-(dihydrogen phosphate), disodium salt
Estracyt
Estramustine phosphate disodium salt
NSC 89199
Ro 21-8837/001
Estra-1,3,5(10)-trien-3,17-diol-(17beta)-, 3-(Bis(2-chlorethyl)carbamat) 17-(Dihydrogen-phosphat), Dinatriumsalz
(17-beta)-Estra-1,3,5(10)-triene-3,17-diol 3-(bis(2-chloroethyl)carbamate) 17-(dihydrogenphosphate) disodium salt
1,3,5(10)-Estratriene-3,17β-diol 3-[bis(2-chloroethyl)carbamate]17-[phosphoric acid disodium] salt
物理化學(xué)性質(zhì)
| 報(bào)價(jià)日期 | 產(chǎn)品編號(hào) | 產(chǎn)品名稱 | CAS號(hào) | 包裝 | 價(jià)格 |
| 2026/07/06 | S2441 | 雌莫司汀磷酸鈉 Estramustine phosphate sodium | 52205-73-9 | 25mg | 970.74元 |
| 2026/07/06 | S2441 | 雌莫司汀磷酸鈉 Estramustine phosphate sodium | 52205-73-9 | 1g | 7944.3元 |
| 2026/06/05 | HY-13627 | 雌莫司汀磷酸鈉 Estramustine phosphate sodium | 52205-73-9 | 5 mg | 440元 |
常見(jiàn)問(wèn)題列表
Estramustine phosphate sodium (1 μg/mL) treatment suppressed PC3 cell growth.
Estramustine phosphate sodium (2 μg/mL) treatment significantly elevates phosphatidylserine eversion amount on PC3 cells. Estramustine phosphate sodium induces PC3 cell apoptosis.
Estramustine phosphate sodium (2 μg/mL) treatment decreases MiR-31 level. Estramustine phosphate odium induces s prostate cancer cell line PC3 apoptosis through reducing miR-31.
Estramustine phosphate sodium, a unique antitumour agent, is selectively taken up by prostate cells and exerts antineoplastic effects by interfering with microtubule of dynamics and by reducing plasma levels of testosterone.
Estrone and estradiol, products of the metabolism of Estramustine phosphate sodium, have shown antigonadotrophic activity resulting in reduced testosterone levels similar to those achieved after surgical castration.
Estramustine phosphate sodium (4-12 mg/kg; intraperitoneal injection; daily; for 2 weeks) inhibits PAC120 tumor growth 53% by day 35.
| Animal Model: | Swiss nu/nu (nude) male mice (5-week-old) bearing PAC120 tumors |
| Dosage: | 4 mg/kg, 12 mg/kg |
| Administration: | Intraperitoneal injection; daily; for 2 weeks |
| Result: | Suppressed the development of skin lesions and resulted in a dissociation between DTH response and antibody production. |