53101-49-8
中文名稱
(R)-(+)-6-羥基-2,5,7,8-四甲基色滿-2-羧酸
英文名稱
(R)-(+)-6-HYDROXY-2,5,7,8-TETRAMETHYLCHROMAN-2-CARBOXYLIC ACID
CAS
53101-49-8
分子式
C14H18O4
分子量
250.29
MOL 文件
53101-49-8.mol
53101-49-8 結構式
基本信息
中文別名
(R)-(+)-6-羥基-2,5,7,8-四甲基沒-2-羧酸(R)-(+)-6-羥基-2,5,7,8-四甲基色烷-2-羧酸
(R)-(+)-6-羥基-2,5,7,8-四甲基色滿-2-羧酸
英文別名
(R)-Trolox(R)-Trolox D5
Trolox (R)-Isomer
Trolox Impurity 1 (Trolox (R)-Isomer)
(R)-(+)-6-hydroxy-2,5,7,8-tetramethyl-chroman-2-C
(2R)-2,5,7,8-Tetramethyl-6-hydroxychroman-2-carboxylic acid
(R)-(+)-6-HYDROXY-2,5,7,8-TETRAMETHYLCHROMAN-2-CARBOXYLIC ACID
(R)-(+)-6-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid 98%
(R)-3,4-Dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-carboxylic acid
(2R)-6-Hydroxy-2,5,7,8-tetramethyl-3,4-dihydro-2H-1-benzopyran-2-carboxylic acid
物理化學性質
熔點162 °C (dec.) (lit.)
沸點450.3±45.0 °C(Predicted)
密度1.219±0.06 g/cm3(Predicted)
儲存條件-20°C儲存
溶解度DMSO: 250 mg/mL (998.84 mM)
酸度系數(pKa)3.35±0.20(Predicted)
形態(tài)Solid
顏色White to off-white
旋光度 (Optical Rotation)[α]27/D +65°, c = 1.2 in ethanol
InChI1S/C14H18O4/c1-7-8(2)12-10(9(3)11(7)15)5-6-14(4,18-12)13(16)17/h15H,5-6H2,1-4H3,(H,16,17)/t14-/m1/s1
InChIKeyGLEVLJDDWXEYCO-CQSZACIVSA-N
SMILESCc1c(C)c2O[C@](C)(CCc2c(C)c1O)C(O)=O
安全數據
警示詞警告
危險性描述H315-H319-H335
危險品標志Xi
危險類別碼36/37/38
安全說明26-37/39
WGK Germany3
海關編碼9999999999
存儲類別11 - Combustible Solids
危險性類別Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
Skin Irrit. 2
STOT SE 3
(R)-(+)-6-羥基-2,5,7,8-四甲基色滿-2-羧酸價格(試劑級)
| 報價日期 | 產品編號 | 產品名稱 | CAS號 | 包裝 | 價格 |
| 2026/06/05 | HY-101445AR | (R)-(+)-6-羥基-2,5,7,8-四甲基色滿-2-羧酸 (R)-Trolox (Standard) | 53101-49-8 | 5 mg | 400元 |
| 2026/06/05 | HY-101445AR | (R)-(+)-6-羥基-2,5,7,8-四甲基色滿-2-羧酸 (R)-Trolox (Standard) | 53101-49-8 | 10 mg | 600元 |
| 2026/06/05 | HY-101445AR | (R)-(+)-6-羥基-2,5,7,8-四甲基色滿-2-羧酸 (R)-Trolox (Standard) | 53101-49-8 | 25 mg | 1100元 |
常見問題列表
生物活性
(R)-Trolox 是水溶性維生素 E 類似物，是一種競爭性酪氨酸酶抑制劑，Ki 值為 0.83 mM，ID50 值為 1.88 mM。(R)-Trolox 具有比 (S) 對映異構體更強的酪氨酸酶親和力 (Ki 值為 0.61 mM)。體外研究
As compared to the control containing no inhibitor, DMSO suppresses the tyrosinase activity at tested levels, 100 and 200 μL in a total volume of 3.0 mL. The inhibition of DMSO on the mushroom tyrosinase is dosedependent. Additions of DMSO at the two levels in the tyrosinase digests containing (R)-Trolox ((R)-HTCCA) results in further inhibitions of the tyrosinase activity. The influence of the DMSO on the inhibitory effects of (R)-Trolox against the tyrosinase is also dose-dependent.