56-94-0
中文名稱
地美溴銨
英文名稱
Demecarium bromide
CAS
56-94-0
EINECS 編號(hào)
200-301-9
分子式
C32H52Br2N4O4
分子量
716.59
MOL 文件
56-94-0.mol
更新日期
2026/06/17 11:16:49
56-94-0 結(jié)構(gòu)式
基本信息
中文別名
3,3'-(1,10-亞癸基雙((甲基亞氨)甲酰氧基))雙(N,N,N-三甲基苯銨))二溴化物地美溴銨
代麥卡
待買卡農(nóng)
英文別名
3,3'-(1,10-decanediylbis((methylimino)carbonyloxy))bis(n,n,n-trimethyl-benzenaminium)) dibromidedemecarium bromide
(m-hydroxyphenyl)trimethylammoniumbromidedecamethylenebis(methylcarbamate)
2br
ammonium,(m-hydroxyphenyl)trimethyl-,bromide,decamethylenebis(methylcarbamat
bc48
benzenaminium,3,3’-(1,10-decanediylbis((methylimino)carbonyloxy))bis(n,n,n-t
benzenaminium,3,3’-(1,10-decanediylbis((methylimino)carbonyloxy))bis(n,n,n-tri
decamethylenebis(m-dimethylaminophenyl-n-methylcarbamate)dimethobromide
decamethylenebis(n-methylcarbamicacidm-dimethylaminophenylester)bromomethyl
demekariumbromide
demekastigminebromide
e)(2:1)
frumtosnil
humorsol
n,n’-bis(3-trimethylammoniumphenoxycarbonyl)-n,n’-dimethyldecamethylenediamine
tonilen
tosmicil
tosmilen
tosmilene
所屬類別
原料藥：擬膽堿藥物理化學(xué)性質(zhì)
熔點(diǎn)162-167 °C (decomp)
儲(chǔ)存條件-20°C儲(chǔ)存
溶解度DMSO:160.0(Max Conc. mg/mL);223.28(Max Conc. mM)
形態(tài)固體
顏色白色
主要應(yīng)用pharmaceutical (small molecule)
InChIKeyYHKBUDZECQDYBR-UHFFFAOYSA-L
SMILESC1(=CC=CC([N+](C)(C)C)=C1)OC(=O)N(C)CCCCCCCCCCN(C)C(=O)OC1=CC=CC([N+](C)(C)C)=C1.[Br-].[Br-]
CAS 數(shù)據(jù)庫(kù)56-94-0(CAS DataBase Reference)
安全數(shù)據(jù)
警示詞警告
危險(xiǎn)性描述H302-H315-H319-H335
防范說(shuō)明P261-P305+P351+P338
WGK GermanyWGK 3
海關(guān)編碼2924296000
存儲(chǔ)類別6.1A - Combustible acute toxic Cat. 1 and 2
very toxic hazardous materials
very toxic hazardous materials
危險(xiǎn)性類別Acute Tox. 2 Oral
毒害物質(zhì)數(shù)據(jù)56-94-0(Hazardous Substances Data)
常見問(wèn)題列表
膽堿酯酶抑制藥
地美溴銨，西藥名。常用劑型為滴眼劑。為膽堿酯酶抑制藥。用于縮瞳或用于開角型青光眼。生物活性
Demecarium Bromide (BC-48) 是一種有效的 cholinesterase 抑制劑，Kiapp 值為 0.15 μM。Demecarium Bromide 可用于青光眼的研究。靶點(diǎn)
Kiapp: 0.15 μM (Cholinesterase)
體內(nèi)研究
Demecarium Bromide (0.125 and 0.5%) causes long-term miosis and decreases intraocular pressure (IOP) in beagles with both normotensive eyes and inherited glaucoma.