62666-20-0
62666-20-0 結(jié)構(gòu)式
基本信息
普羅加比
哈羅加比
氟柳雙胺
化合物 T16581
化合物PROGABIDE
4-[[(4-氯苯基)(5-氟-2-羥基苯基)亞甲基]氨基]丁酰胺
4-[[(Z)-(4-氯苯基)-(3-氟-6-氧代-1-環(huán)己-2,4-二烯亞基)甲基]氨基]丁酰胺
Gabrene
SL-76．002
progabide
Halogabide
C-abren(e)
Progabide USP/EP/BP
4-[α-(p-Chlorophenyl)-5-fluoro-2-hydroxybenzylideneamino]butyramide
4-[[(4-Chlorophenyl)(5-fluoro-2hydroxyphenyl)methylene]amino]butanamide
(E)-4-((4-chlorophenyl)(5-fluoro-2-hydroxyphenyl)methyleneamino)butanamide
物理化學(xué)性質(zhì)
制備方法
| 報價日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS號 | 包裝 | 價格 |
| 2026/06/05 | HY-A0173R | 普羅加比 Progabide (Standard) | 62666-20-0 | 5 mg | 1000元 |
| 2026/06/05 | HY-A0173R | 普羅加比 Progabide (Standard) | 62666-20-0 | 10 mg | 1660元 |
| 2026/06/05 | HY-A0173R | 普羅加比 Progabide (Standard) | 62666-20-0 | 25 mg | 3000元 |
常見問題列表
GABA receptor
Progabide is a gamma-aminobutyric acid receptor (GABA) agonist. Doses of 50, 100 and 200 mg/kg Progabide given IP to male Wistar rats increase the plasma corticosterone levels by 244, 365 and 476% respectively (t=6.44 to12.55, p<0.01). 10 mg/kg of Progabide fails to change the concentration of corticosterone in plasma (t=0.76, N.S.). The increased plasma corticosterone level induced by administration of 200 mg/kg Progabide is evident 30 (t=2.625, p<0.05), 60 (t=13.13, p<0.001) and 120 min (t=4.07, p<0.01) after drug injection, but returns to the control value 240 min after drug injection (t=0.86, N.S.). The greatest corticosterone rise (compare with the corresponding control) is reached 60 min following the administration of Progabide.