63612-50-0
中文名稱
尼魯米特
英文名稱
Nilutamide
CAS
63612-50-0
分子式
C12H10F3N3O4
MDL 編號
MFCD00864670
分子量
317.22
MOL 文件
63612-50-0.mol
更新日期
2026/06/29 12:05:41
63612-50-0 結(jié)構(gòu)式
基本信息
中文別名
里奴內(nèi)酰胺尼魯米特
尼魯他胺/尼魯米特
5,5-二甲基-3-[4-硝基-3-(三氟甲基)苯基]-2,4-咪唑烷二酮
尼魯他胺
英文別名
5,5-DIMETHYL-3-[4-NITRO-3-(TRIFLUOROMETHYL)PHENYL]-2,4-IMIDAZOLIDINEDIONEANANDRON
NILUTAMIDE
RU-23908
1-(3’-trifluoromethyl-4’-nitrophenyl)-4,4-dimethylimidazolidine-2,5-dione
5,5-dimethyl-3-(4-nitro-3-(trifluoromethyl)phenyl)-4-imidazolidinedione
5,5-dimethyl-3-(alpha,alpha,alpha-trifluoro-4-nitro-m-tolyl)hydantoin
nilutamida
Nilutamide(other anti-cancers)
1-3-Trifluoromethyl-4-nitrophenyl)-4,4-dimethylimidazoline-2,5-dione
5,5-Dimethyl-3-[4-nitro-3-(trifluoromethyl)phenyl]-2,4-imidazolidinedion
Nilandron
Nilandrone
RU 23908-10
Anandron, RU-23908, 5,5-Dimethyl-3-[4-nitro-3-(trifluoromethyl)phenyl]-2,4-imidazolidinedione
5，5-Dimethyl-3-[4-nitrcr3-(trifluoromethyl)phenyl]-2，4-imidazolidinedione
2,4-Imidazolidinedione, 5,5-dimethyl-3-(4-nitro-3-(trifluoromethyl)phenyl)-
5,5-Dimethyl-3-[4-nitro-3-(trifluoromethyl)phenyl]imidazolidine-2,4-dione
5,5-Dimethyl-3-[4-nitro-3-(trifluoromethyl)phenyl]hydantoin
所屬類別
藥物: 激素及其有關(guān)藥物: 性激素與促性激素物理化學性質(zhì)
外觀性狀從乙醇結(jié)晶，熔點149℃。急性毒性LD50雄小鼠，雄大鼠(mg/kg)：215，195口服；180，135腹腔注射。
熔點1490C
密度1.463±0.06 g/cm3(Predicted)
儲存條件Sealed in dry,Room Temperature
溶解度Very slightly soluble in water, freely soluble in acetone, soluble in anhydrous ethanol.
酸度系數(shù)(pKa)7.59±0.70(Predicted)
形態(tài)solid
顏色Light yellow to yellow
主要應(yīng)用pharmaceutical (small molecule)
InChIInChI=1S/C12H10F3N3O4/c1-11(2)9(19)17(10(20)16-11)6-3-4-8(18(21)22)7(5-6)12(13,14)15/h3-5H,1-2H3,(H,16,20)
InChIKeyXWXYUMMDTVBTOU-UHFFFAOYSA-N
SMILESC1(=O)NC(C)(C)C(=O)N1C1=CC=C([N+]([O-])=O)C(C(F)(F)F)=C1
CAS 數(shù)據(jù)庫63612-50-0(CAS DataBase Reference)
安全數(shù)據(jù)
警示詞危險
危險性描述H301-H360
危險品標志T
危險類別碼60-25
安全說明53-36/37/39-45
危險品運輸編號UN 2811 6.1/PG 3
WGK Germany3
RTECS號NI9453300
危險等級6.1
海關(guān)編碼2933210000
存儲類別6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects
toxic compounds or compounds which causing chronic effects
危險性類別Acute Tox. 3 Oral
Repr. 1B
Repr. 1B