5-PREGNEN-3BETA-OL-20-ONE-16ALPHA-CARBONITRILE
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- CAS-Nr.
- 1434-54-4
- Englisch Name:
- 5-PREGNEN-3BETA-OL-20-ONE-16ALPHA-CARBONITRILE
- Synonyma:
- pcn;sc4674;U-14975;16-alpha-cyanopregnenolone;pregnenolone-16α-carbonitrile;Pregnenolone 16α-carbonitrile;5-PREGNEN-16α-CYANO-3β-OL-20-ONE;PREGNENOLONE-16ALPHA-CARBONITRILE;16α-Cyano-3β-hydroxypregn-5-en-20-one;5-pregnen-3B-ol-20-one-16A-carbonitrile
- CBNumber:
- CB4150567
- Summenformel:
- C22H31NO2
- Molgewicht:
- 341.49
- MOL-Datei:
- 1434-54-4.mol
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5-PREGNEN-3BETA-OL-20-ONE-16ALPHA-CARBONITRILE Eigenschaften
- Schmelzpunkt:
- 225-228 °C(Solv: methanol (67-56-1); benzene (71-43-2))
- Siedepunkt:
- 508.5±50.0 °C(Predicted)
- Dichte
- 1.13±0.1 g/cm3(Predicted)
- Flammpunkt:
- 93 °C
- storage temp.
- 2-8°C
- L?slichkeit
- Acetonitrile: 1 mg/ml; Ethanol: 1 mg/ml; Methanol: 1 mg/ml
- pka
- 14.95±0.70(Predicted)
- Aggregatzustand
- White to off-white solid.
- Farbe
- White to off-white
- Biologische Quelle
- synthetic (organic)
- InChI
- 1S/C22H31NO2/c1-13(24)20-14(12-23)10-19-17-5-4-15-11-16(25)6-8-21(15,2)18(17)7-9-22(19,20)3/h4,14,16-20,25H,5-11H2,1-3H3/t14-,16-,17+,18-,19-,20-,21-,22-/m0/s1
- InChIKey
- VSBHRRMYCDQLJF-ZDNYCOCVSA-N
- SMILES
- C[C@@]12[C@](C[C@@H](C#N)[C@@H]2C(C)=O)([H])[C@]3([H])CC=C4C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC1
- EPA chemische Informationen
- Pregn-5-ene-16-carbonitrile, 3-hydroxy-20-oxo-, (3.beta.,16.alpha.)- (1434-54-4)
Sicherheit
| WGK Germany |
3 |
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| RTECS-Nr. |
TU4536500 |
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| Speicherklasse |
11 - Combustible Solids |
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5-PREGNEN-3BETA-OL-20-ONE-16ALPHA-CARBONITRILE Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
Pregnenolone Carbonitrile is a glucocorticoid receptor antagonist that induces the expression of the CYP3A family of steroid hydroxylases and modulates sterol and bile acid biosynthesis in vivo. Pregnenolone Carbonitrile is an an activator of rat pregnane X receptor (PXR).
Biochem/physiol Actions
Pregnenolone-16a-carbonitrile (PCN) is a glucocorticoid receptor antagonist and a PXR (pregnane X receptor) activator.
5-PREGNEN-3BETA-OL-20-ONE-16ALPHA-CARBONITRILE Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
5-PREGNEN-3BETA-OL-20-ONE-16ALPHA-CARBONITRILE Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 58)Lieferanten
1434-54-4()Verwandte Suche:
- 5-PREGNEN-3BETA-OL-20-ONE-16ALPHA-CARBONITRILE
- 5-pregnen-3B-ol-20-one-16A-carbonitrile
- (3S,8S,9S,10R,13S,14S,16R,17S)-17-acetyl-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-16-carbonitrile
- (3S,8S,9S,10R,13S,14S,16R,17S)-17-ethanoyl-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-16-carbonitrile
- pregnenolone-16α-carbonitrile
- 16α-Cyano-3β-hydroxypregn-5-en-20-one
- U-14975
- 16-alpha)-3-hydroxy-20-oxopregn-5-ene-16-carbonitrile(3-bet
- 16-alpha-cyanopregnenolone
- 3beta-hydroxy-20-oxo-pregn-5-ene-16-alpha-carbonitril
- 3-hydroxy-20-oxo-,(3-beta,16-alpha)-pregn-5-ene-16-carbonitril
- sc4674
- PREGNENOLONE-16ALPHA-CARBONITRILE
- Pregn-5-ene-16-carbonitrile, 3-hydroxy-20-oxo-, (3β,16α)-
- CYPs,Cytochrome P450,P4503A,orally,Pregnenolone Carbonitrile,Pregnenolone 16α-carbonitrile,Inhibitor,PXR,cytochrome,inhibit
- 5-PREGNEN-16α-CYANO-3β-OL-20-ONE
- Pregnenolone 16α-carbonitrile
- Pregnenolone-16alpha-carbonitrile, Cytochrome P-450 inducer
- Pregnenolone Carbonitrile, 10 mM in DMSO
- 5-Pregnen-3β-ol-20-one-16α-carbonitrile, CAS 1434-54-4
- pcn
- 1434-54-4
- C22H31NO2
- BioChemical
- Cell Signaling and Neuroscience
- Cell Biology
- Cytokines, Growth Factors and Hormones
- Corticosterone
- Hormones
- Steroid Hormones
