Quinapril hydrochloride
|
|
|
- CAS-Nr.
- 82586-55-8
- Englisch Name:
- Quinapril hydrochloride
- Synonyma:
- QUINAPRIL HCL;ACCUPRIL;Korec;Conan;CI-906;Acupril;ccupril;ACCUPRO;Acequin;Acuitel
- CBNumber:
- CB8100984
- Summenformel:
- C25H31ClN2O5
- Molgewicht:
- 474.98
- MOL-Datei:
- 82586-55-8.mol
|
Quinapril hydrochloride Eigenschaften
- Schmelzpunkt:
- 120-130°C
- alpha
- D23 +14.5° (c = 1.2 in ethanol) (Klutchko); D25 +15.4° (c = 2 in methanol) (Goel, Krolls)
- storage temp.
- 2-8°C
- L?slichkeit
- H2O: >10mg/mL
- Aggregatzustand
- solid
- Farbe
- white
- Wasserl?slichkeit
- H2O: >10mg/mL
- InChIKey
- IBBLRJGOOANPTQ-ZKASTLJSNA-N
- SMILES
- N1(C(=O)[C@H](C)N[C@H](C(=O)OCC)CCC2C=CC=CC=2)CC2C(=CC=CC=2)C[C@H]1C(=O)O.Cl |&1:3,6,28,r|
- CAS Datenbank
- 82586-55-8(CAS DataBase Reference)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| S-S?tze: |
22-24/25 |
|
|
| WGK Germany |
2 |
|
|
| RTECS-Nr. |
NW7176000 |
|
|
| HS Code |
2933492250 |
|
|
| Speicherklasse |
6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects |
|
|
| Hazard Classifications |
Repr. 2
STOT RE 1 |
|
|
| Giftige Stoffe Daten |
82586-55-8(Hazardous Substances Data) |
|
|
| Toxizit?t |
Freely sol in aq solvents. LD50 in male, female mice, rats (mg/kg): 1739, 1840, 4280, 3541 orally; 504, 523, 158, 107 i.v. (Kaplan, 1989) |
|
|
| Bildanzeige (GHS) |
|
| Alarmwort |
Warnung
|
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H303 |
May be harmfulif swallowed |
Acute toxicity,oral |
Category 5 |
|
|
P312 |
| H361 |
Kann vermutlich die Fruchtbarkeit beeintr?chtigen oder das Kind im Mutterleib sch?digen. |
Reproduktionstoxizit?t |
Kategorie 2 |
Warnung |
|
P201, P202, P281, P308+P313, P405,P501 |
|
| Sicherheit |
| P201 |
Vor Gebrauch besondere Anweisungen einholen. |
| P202 |
Vor Gebrauch alle Sicherheitshinweise lesen und verstehen. |
| P270 |
Bei Gebrauch nicht essen, trinken oder rauchen. |
| P281 |
Vorgeschriebene pers?nliche Schutzausrüstung verwenden. |
| P301+P312 |
BEI VERSCHLUCKEN: Bei Unwohlsein GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen. |
| P308+P313 |
BEI Exposition oder falls betroffen: ?rztlichen Rat einholen/?rztliche Hilfe hinzuziehen. |
| P403 |
An einem gut belüfteten Ort aufbewahren. |
|
Quinapril hydrochloride Chemische Eigenschaften,Einsatz,Produktion Methoden
S-S?tze Betriebsanweisung:
S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.
Chemische Eigenschaften
White Crystalline Solid
Verwenden
Quinapril hydrochloride has been used as an angiotensin-converting enzyme (ACE) inhibitor to study its effects on renal tubular epithelial cell proliferation in human renal tubular epithelial cells. It has also been used as an ACE inhibitor to evaluate its effects on the expression of angiotensin II (AII) in patient-derived Atheroma samples.
Allgemeine Beschreibung
Quinapril hydrochloride,(S)-[(S)-N-[(S)21-carboxy3-phenylpropyl]alanyl]-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid 1-ethyl ester hydrochloride(Acuretic), forms the diacid quinaprilate in thebody. It is more potent than captopril and equipotent to theactive form of enalapril.
Quinapril hydrochloride Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Quinapril hydrochloride Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 322)Lieferanten
82586-55-8()Verwandte Suche:
- Acupril
- Korec
- Korectic
- Quinazil
- ccupril
- (3S-(2(R*(R*)),3R*))-2-(2-((1-(Ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid monohydrochloride
- (3S)-2-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid hydrochloride
- (3S)-2-[(2S)-2-[[(1S)-1-carbethoxy-3-phenyl-propyl]amino]propanoyl]-3,4-dihydro-1H-isoquinoline-3-carboxylic acid hydrochloride
- (3S)-2-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenyl-butan-2-yl]amino]propanoyl]-3,4-dihydro-1H-isoquinoline-3-carboxylic acid hydrochloride
- (3S)-2-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]-3,4-dihydro-1H-isoquinoline-3-carboxylic acid hydrochloride
- Quinapril Hydrochloride (400 mg)
- Quinapril hydrochlor
- Quinapril hydrochloride (Accupril)
- Quinapril HCl API
- Conan
- Naripshin
- (3S)-2-[(2S)-2-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid, hydrochloride (1:1)
- Quinapril for peak identification
- Quinapril for system suitability
- Quinapril hydrochloride, >=99%
- 3-isoquinolinecarboxylicacid,1,2,3,4-tetrahydro-2-(2-((1-(ethoxycarbonyl)-3-p
- monohydrochloride,(3s-(2(r*(r*)),3r*))-henylpropyl)amino)-1-oxopropyl)
- CI-906
- ACCUPRIN
- ACCUPRO
- (3S)-2-[(2S)-2-[[(1S)-1-(ETHOXYCARBONYL)-3-PHENYLPROPYL]AMINO]-1-OXOPROPYL]-1,2,3,4-TETRAHYDRO-3-ISOQUINOLINECARBOXYLIC ACID HYDROCHLORIDE
- QUINAPRIL HYDROCHLORIDE
- PD-109452-2
- QUINAPRIL HYDROCHLORIDE, RELATED COMPOUND B3-ISOQUINOLINECARBOXYLIC ACID, 2-[2-[(1-CARBOXY-3-PHENYLPROPYL)AMINO]-1-OXOPROPYL]-1,2,3,4-TETRAHYDRO-,[3S-[2[R*(R*)],3R*]]- USP STANDARD
- QUINAPRIL HYDROCHLORIDE, RELATED COMPOUND A ETHYL[3S-[2(R*),3A,11A BETA]]-1,3,4,6,11,11A-HEXAHYDRO-3-METHYL-1,4-DIOXO-ALPHA-(2-PHENYLETHYL)-2H-PYRAZINO[1,2-B]ISOQUINOLINE-2-ACETATE USP STANDARD
- QuinaprilHclC25H30N205.HC1
- CI-906, PD-109452-2, Accupril, Accuprin, Accupro
- Accupron
- 3-Isoquinolinecarboxylic acid, 2-[(2S)-2-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1,2,3,4-tetrahydro-, monohydrochloride, (3S)- (9CI)
- 3-Isoquinolinecarboxylic acid, 2-[2-[[1-(ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1,2,3,4-tetrahydro-, monohydrochloride, [3S-[2[R*(R*)],3R*]]-
- Acequide
- Acequin
- Acuitel
- Acuprel
- (S)-2-[(S)-N-[(S)-1-Carboxy-3-phenylpropyl]alanyl]-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid, 1-ethyl ester, monohydrochloride
- (3S)-2-[(2S)-2-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}propanoyl]-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid hydrochloride
- Quinapril for system suitability CRS
- Quinapril hydrochloride CRS
- Quinapril for peak identification CRS
- Quinapril hydrochloride USP/EP/BP
- Quinapril HCl (CI-906)
- WIDELY Quinapril HCL
- Quinapril HydrochlorideQ: What is
Quinapril Hydrochloride Q: What is the CAS Number of
Quinapril Hydrochloride Q: What is the storage condition of
Quinapril Hydrochloride Q: What are the applications of
Quinapril Hydrochloride
- Quinapril Hydrochloride (1593401)
- (S)-2-(((S)-1-Ethoxy-1-oxo-4-phenylbutan-2-yl)-L-alanyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid hydrochloride
- ACCUPRIL
- Quinapril hydrochloride in methanol
- Acrylamide Impurity 5
- Quinapril hydrochloride, ACE inhibitor
- Quinapril hydrochloride, 10 mM in DMSO
- QUINAPRIL HYDROCHLORIDE USP
- Quinapril HCl - Bio-X ?
- Quinapril Hydrocloride
