Moxonidine
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- CAS-Nr.
- 75438-57-2
- Englisch Name:
- Moxonidine
- Synonyma:
- Moxonidine-d3;Moxonidin;4-Chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-6-methoxy-2-methyl-5-pyrimidinamine;Cynt;LoMox;be5895;Nucynt;bdf5895;Norcynt;MOXONIDINE
- CBNumber:
- CB8121013
- Summenformel:
- C9H12ClN5O
- Molgewicht:
- 241.68
- MOL-Datei:
- 75438-57-2.mol
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Moxonidine Eigenschaften
- Schmelzpunkt:
- 217-219° (dec)
- Siedepunkt:
- 364.7±52.0 °C(Predicted)
- Dichte
- 1.52±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C
- L?slichkeit
- Very slightly soluble in water, sparingly soluble in methanol, slightly soluble in methylene chloride, very slightly soluble in acetonitrile.
- Aggregatzustand
- Solid
- pka
- 7.11±0.10(Predicted)
- Farbe
- White to Almost white
- Wasserl?slichkeit
- 800.3mg/L(temperature not stated)
- Merck
- 14,6293
- Major Application
- pharmaceutical (small molecule)
- InChI
- 1S/C9H12ClN5O/c1-5-13-7(10)6(8(14-5)16-2)15-9-11-3-4-12-9/h3-4H2,1-2H3,(H2,11,12,15)
- InChIKey
- WPNJAUFVNXKLIM-UHFFFAOYSA-N
- SMILES
- Clc1nc(nc(c1N=C2NCCN2)OC)C
- CAS Datenbank
- 75438-57-2(CAS DataBase Reference)
Moxonidine Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Moxonidine, which is structurally related to clonidine, is a new centrally acting
antihypertensive that acts as a stronger agonist at imidazole receptors and a weaker
agonist at α2-adrenergic receptors than clonidine. It is also reported to have less side
effects and a much reduced potential to produce a rebound in blood pressure on
withdrawal. Clinically, moxonidine appears to have comparable antihypertensive
efficacy with the ACE inhibitors and calcium antagonists.
Chemische Eigenschaften
White Solid
Verwenden
Moxonidine is an antihypertensive agent.
Biologische Aktivit?t
Mixed I 1 imidazoline receptor and α 2 -adrenergic agonist; displays 40-fold higher affinity for I 1 receptors versus α 2 -adrenoceptors. Centrally acting antihypertensive agent.
Moxonidine Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Moxonidine Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 260)Lieferanten
75438-57-2()Verwandte Suche:
- MOXONIDINE
- MOXONIDINE HCL
- 4-chloro-n-(4,5-dihydro-1h-imidazol-2-yl)-6-methoxy-2-methyl-5-pyrimidinamin
- bdf5895
- be5895
- BDF-5895 HCL
- 4-CHLORO-6-METHOXY-2-METHYL-5-(2-IMIDAZOLIN-2-YL)AMINOPYRIMIDINE HCL
- 4-CHLORO-N-(4,5-DIHYDRO-1H-IMIDAZOL-2-YL)-6-METHOXY-2-METHYL-5-PYRIMIDINAMINE HYDROCHLORIDE
- 4-Chloro-5-(2-imidazolin-2-ylamino)-6-methoxy-2-methylpyrimidine
- MOXONIDINE/4-CHLORO-N-(4,5-DIHYDRO-1H-2-IMIDAZOLYL)-6-METHOXY-2-METHYL-5-PYRAMINE
- 4-Chloro-N-(4，5-dihydro-1H-imidaml-2-y1)-6-methoxy-2-methyl-5-pyrimidinamine
- Cynt
- Physioterls
- 4-Chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-6-methoxy-2-methylpyrimidin-5-amine
- Norcynt
- (4-chloro-6-methoxy-2-methyl-pyrimidin-5-yl)-(4,5-dihydro-1H-imidazol-2-yl)amine
- 5-Pyrimidinamine, 4-chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-6-methoxy-2-methyl-
- 2-(6-Chloro-4-Methoxy-2-MethylpyriMidin-5-ylaMino)-2-iMidazoline
- LoMox
- NorMoxocin
- Nucynt
- Physiotens
- 4-Chloro-6-methoxy-2-methyl-5-(2-imidazolin-2-yl)aminopyrimidine hydrochloride
- 4-chloro-N-imidazolidin-2-ylidene-6-methoxy-2-methylpyrimidin-5-amine
- Moxonidine >
- Moxonidine CRS
- Moxonidine USP/EP/BP
- Moxonidine (BDF5895)
- Moxonidine 13CD3Q: What is
Moxonidine 13CD3 Q: What is the CAS Number of
Moxonidine 13CD3 Q: What is the storage condition of
Moxonidine 13CD3
- MoxonidineQ: What is
Moxonidine Q: What is the CAS Number of
Moxonidine Q: What is the storage condition of
Moxonidine Q: What are the applications of
Moxonidine
- Moxonidine, 10 mM in DMSO
- Moxonidine 1.0 mg/ml in Methanol
- 4-chloro-N-(4,5-dihydro-1H-imidazole-2-yl)-6-methoxy-2-methylpyrimidine-5-amine
- Moxonidine EP Impurity 2
- 4-Chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-6-methoxy-2-methyl-5-pyrimidinamine
- Moxonidine-d3
- Moxonidin
- 75438-57-2
- C9H12ClN5O
- C9H12Cl5O
- Cardiovascular APIs
- API
- Aromatics
- Heterocycles
- Intermediates & Fine Chemicals
- Pharmaceuticals
- API's
