ChemicalBook >> CAS DataBase List >>1-Boc-4-(5-Methyl-1,3,4-oxadiazol-2-yl)piperidine

1-Boc-4-(5-Methyl-1,3,4-oxadiazol-2-yl)piperidine

1-Boc-4-(5-Methyl-1,3,4-oxadiazol-2-yl)piperidine structure

CAS No.: 280110-69-2

Chemical Name:: 1-Boc-4-(5-Methyl-1,3,4-oxadiazol-2-yl)piperidine

Synonyms: 1-Boc-4-(5-Methyl-1,3,4-oxadiazol-2-yl);Benzoicacid,8-(chlorosulfonyl)-,methylester;1-Boc-4-(5-Methyl-1,3,4-oxadiazol-2-yl)piperidine;tert-Butyl 4-(5-methyl-1,3,4-oxadiazol-2-yl)piperidine-1-carboxylate;1-Piperidinecarboxylic acid, 4-(5-methyl-1,3,4-oxadiazol-2-yl)-, 1,1-dimethylethyl ester

CBNumber:: CB42549851

Molecular Formula:: C13H21N3O3

Molecular Weight:: 267.32

MDL Number:: MFCD13193509

MOL File:: 280110-69-2.mol

MSDS File:: SDS

Last updated:2026-05-28 02:40:18

Product description	Number	Pack Size	Price
1-Boc-4-(5-Methyl-1,3,4-oxadiazol-2-yl)piperidine	073780	250.00mg	$629
1-Boc-4-(5-Methyl-1,3,4-oxadiazol-2-yl)piperidine	073780	1.00g	$1357
1-Boc-4-(5-Methyl-1,3,4-oxadiazol-2-yl)piperidine 97%	AA007LRM	100mg	$12
1-Boc-4-(5-Methyl-1,3,4-oxadiazol-2-yl)piperidine 97%	AA007LRM	250mg	$29
1-Boc-4-(5-Methyl-1,3,4-oxadiazol-2-yl)piperidine 97%	AA007LRM	1g	$52

Request For Quotation

1-Boc-4-(5-Methyl-1,3,4-oxadiazol-2-yl)piperidine Properties

Melting point	69 °C
Boiling point	384.0±52.0 °C(Predicted)
Density	1.140±0.06 g/cm3(Predicted)
storage temp.	Sealed in dry,Room Temperature
pka	-2.58±0.40(Predicted)
Appearance	Off-white to light yellow Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H332-H335
Precautionary statements	P261-P280-P305+P351+P338

1-Boc-4-(5-Methyl-1,3,4-oxadiazol-2-yl)piperidine price More Price(32)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Matrix Scientific	073780	1-Boc-4-(5-Methyl-1,3,4-oxadiazol-2-yl)piperidine	280110-69-2	250.00mg	$629	2026-05-18	Buy
Matrix Scientific	073780	1-Boc-4-(5-Methyl-1,3,4-oxadiazol-2-yl)piperidine	280110-69-2	1.00g	$1357	2026-05-18	Buy
aablocks	AA007LRM	1-Boc-4-(5-Methyl-1,3,4-oxadiazol-2-yl)piperidine 97%	280110-69-2	100mg	$12	2026-05-28	Buy
aablocks	AA007LRM	1-Boc-4-(5-Methyl-1,3,4-oxadiazol-2-yl)piperidine 97%	280110-69-2	250mg	$29	2026-05-28	Buy
aablocks	AA007LRM	1-Boc-4-(5-Methyl-1,3,4-oxadiazol-2-yl)piperidine 97%	280110-69-2	1g	$52	2026-05-28	Buy

Product number	Packaging	Price	Buy
073780	250.00mg	$629	Buy
073780	1.00g	$1357	Buy
AA007LRM	100mg	$12	Buy
AA007LRM	250mg	$29	Buy
AA007LRM	1g	$52	Buy

1-Boc-4-(5-Methyl-1,3,4-oxadiazol-2-yl)piperidine Chemical Properties,Uses,Production

Synthesis

4637-24-5

187834-88-4

1-Boc-4-(5-Methyl-1,3,4-oxadiazol-2-yl)piperidine

280110-69-2

To a solution of 9.0 g 1-BOC-4-piperidinecarbohydrazide (37 mmol, 1 eq.) in 40 mL of THF was added 8.1 mL of N,N-dimethylformamide dimethyl acetal (55.4 mmol, 1.5 eq.). The reaction mixture was stirred under nitrogen protection at 50 °C for 4 hours. After completion of the reaction, the solvent was removed under reduced pressure and the residue was dissolved in 40 mL of toluene and 400 mg of p-toluenesulfonic acid was added. The mixture was heated at 100 °C and protected by nitrogen for 18 hours. At the end of the reaction, the volatiles were removed under reduced pressure and the residue was partitioned between dichloromethane and aqueous sodium bicarbonate. The organic phase was dried with magnesium sulfate, filtered and concentrated under reduced pressure. The crude product was purified by silica gel column chromatography with the eluent dichloromethane/methanol (98:2 v/v to 95:5 v/v) to afford 8.07 g of 1-Boc-4-(5-methyl-1,3,4-oxadiazol-2-yl)piperidine as a white solid in 81% yield.1H NMR (400 MHz, CD3OD): δ 1.42 (s, 9H), 1.70 (m , 2H), 2.05 (m, 2H), 2.50 (s, 3H), 3.00 (m, 2H), 3.15 (m, 1H), 4.05 (m, 2H); LCMS: m/z APCl+, 268 [MH]+; Elemental analysis results: C, 58.26%; H, 7.96%; N, 15.78%; theoretical value (C13H21N3O3 ): C, 58.41%; H, 7.92%; N, 15.72%.

References

[1] Patent: US2005/154024, 2005, A1. Location in patent: Page/Page column 22
[2] Patent: WO2006/114706, 2006, A1. Location in patent: Page/Page column 46-47

1-Boc-4-(5-Methyl-1,3,4-oxadiazol-2-yl)piperidine Preparation Products And Raw materials

Raw materials

N,N-Dimethylformamide dimethyl acetal 1,1-Dimethoxy-N,N-dimethylethylamine 1-BOC-ISONIPECOTIC ACID HYDRAZIDE Toluene p-Toluenesulfonic acid monohydrate

Preparation Products

4-(5-methyl-1,3,4-oxadiazol-2-yl)piperidine 2-Methyl-5-(piperidin-4-yl)-1,3,4-oxadiazole hydrochloride

1-Boc-4-(5-Methyl-1,3,4-oxadiazol-2-yl)piperidine Suppliers

Global( 37)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
Fuxin Pharmaceutical	+86-021-021-50872116	contact@fuxinpharm.com	China	9976	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	+8613580539051	joe@yuhengpharm.com	CHINA	21142	58
Aladdin Scientific		tp@aladdinsci.com	United States	52923	58
Nanjing Moldeep Biochemical Co., Ltd.	+86-25-58282389 +86-17351037455	inquiries@moldeep.com	China	20000	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131956	58
Pure Chemistry Scientific Inc.	001-857-928-2050 or 1-888-588-9418	sales@chemreagents.com	United States	10186	62
NovoChemy Ltd.	--	sales@novochemy.com	Germany	6328	58
Shanghai Topbiochem Technology Co., Ltd	+86-21-60341587	sales@topbiochem.com	China	6175	58
SynAsst Chemical.	021-60343070		China	12740	55

Supplier	Advantage
Alchem Pharmtech,Inc.	58
Fuxin Pharmaceutical	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	58
Aladdin Scientific	58
Nanjing Moldeep Biochemical Co., Ltd.	58
Amadis Chemical Company Limited	58
Pure Chemistry Scientific Inc.	62
NovoChemy Ltd.	58
Shanghai Topbiochem Technology Co., Ltd	58
SynAsst Chemical.	55

280110-69-2(1-Boc-4-(5-Methyl-1,3,4-oxadiazol-2-yl)piperidine)Related Search:

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1-Boc-4-(5-Methyl-1,3,4-oxadiazol-2-yl)piperidine tert-Butyl 4-(5-methyl-1,3,4-oxadiazol-2-yl)piperidine-1-carboxylate 1-Boc-4-(5-Methyl-1,3,4-oxadiazol-2-yl) 1-Piperidinecarboxylic acid, 4-(5-methyl-1,3,4-oxadiazol-2-yl)-, 1,1-dimethylethyl ester Benzoicacid,8-(chlorosulfonyl)-,methylester 280110-69-2

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