1-Boc-5-formylindoline
- CAS No.
- 879887-32-8
- Chemical Name:
- 1-Boc-5-formylindoline
- Synonyms
- 1-Boc-5-formylindoline;tert-butyl 5-formylindoline-1-carboxylate;1H-Indole-1-carboxylicacid,5-forMyl-2,3-dihydro-,1,1-diMethylethylester;5-Formyl-2,3-dihydro-1H-indole-1-carboxylic acid 1,1-dimethylethyl ester
- CBNumber:
- CB72534405
- Molecular Formula:
- C14H17NO3
- Molecular Weight:
- 247.29
- MDL Number:
- MFCD12408236
- MOL File:
- 879887-32-8.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| tert-Butyl 5-formylindoline-1-carboxylate ≥95% | OR300270 | 250mg | $75 |
| tert-Butyl 5-formylindoline-1-carboxylate ≥95% | OR300270 | 1g | $273 |
| tert-butyl 5-formylindoline-1-carboxylate | 190087 | 250.00mg | $58 |
| tert-butyl 5-formylindoline-1-carboxylate | 190087 | 1.00g | $141 |
| tert-butyl 5-formylindoline-1-carboxylate | 190087 | 5.00g | $668 |
| More product size | |||
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H319-H335-H302+H312+H332-H315 |
| Precautionary statements | P280-P301+P312-P305+P351+P338 |
| HS Code | 2933998090 |
1-Boc-5-formylindoline price More Price(43)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | OR300270 | tert-Butyl 5-formylindoline-1-carboxylate ≥95% | 879887-32-8 | 250mg | $75 | 2026-06-04 | Buy |
| Apolloscientific | OR300270 | tert-Butyl 5-formylindoline-1-carboxylate ≥95% | 879887-32-8 | 1g | $273 | 2026-06-04 | Buy |
| Matrix Scientific | 190087 | tert-butyl 5-formylindoline-1-carboxylate | 879887-32-8 | 250.00mg | $58 | 2026-05-18 | Buy |
| Matrix Scientific | 190087 | tert-butyl 5-formylindoline-1-carboxylate | 879887-32-8 | 1.00g | $141 | 2026-05-18 | Buy |
| Matrix Scientific | 190087 | tert-butyl 5-formylindoline-1-carboxylate | 879887-32-8 | 5.00g | $668 | 2026-05-18 | Buy |
1-Boc-5-formylindoline Chemical Properties,Uses,Production
Synthesis
261732-38-1
68-12-2
879887-32-8
143262-10-6
5-Bromo-1-tert-butoxycarbonyl dihydroindole (2.0 g, 6.7 mmol) and N,N-dimethylformamide (0.53 mL, 6.7 mmol) were used as raw materials and dissolved in tetrahydrofuran (30 mL). The resulting solution was cooled to -78 °C under stirring and a pentane solution of tert-butyllithium (1.7 M, 10.3 mL, 17.5 mmol) was added slowly and dropwise over 5 min under nitrogen protection. After the reaction mixture was stirred at -78 °C for 2 h, acetic acid (3 mL) was added. Subsequently, the cloudy mixture was slowly warmed to room temperature over 30 min and diluted with ethyl acetate (100 mL). The organic phase was washed sequentially with saturated sodium carbonate solution (2 × 10 mL) and brine (10 mL). The organic layer was dried over anhydrous sodium sulfate, filtered and concentrated in vacuum to give the crude product as an oil. Purification by column chromatography (eluent: ethyl acetate/hexane, 1:9 to 1:1 gradient elution) and vacuum removal of the solvent resulted in the isolation of two products, both white solids: (1) 1-tert-butoxycarbonyldihydroindole (270 mg, 18% yield): 1H NMR (CDCl3, 300 MHz): δ 7.18-7.10 (m, 2H), 6.92 (t 1H, J = 7 Hz), 3.97 (t, 2H, J = 7 Hz), 3.08 (t, 2H, J = 7 Hz), 1.57 (s, 9H); MS (APCI+): m/z 220 ([C13H18NO2 + H]+); (2) 1-Boc-5-formylindoline (650 mg, 39% yield): 1H NMR (CDCl3 , 300 MHz): δ 9.86 (s, 1H), 7.9 (br s, 1H), 7.70-7.65 (m, 2H), 4.06 (t, 2H, J = 7 Hz), 3.15 (t, 2H, J = 7 Hz), 1.58 (s, 9H); MS (ES+): m/z 248 ([C14H18NO3 + H]+).
References
[1] Patent: US2006/63799, 2006, A1. Location in patent: Page/Page column 11
1-Boc-5-formylindoline Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Accela ChemBio Inc. | +1-858-6993322 +86-18019713315 | info@accelachem.com | United States | 21193 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Wuhan Konberd Biotech Co., Ltd | +undefined-18986093962 | admin@konberdbio.com | China | 1378 | 58 |
| Sichuan Biosynce Pharmatech Co., Ltd. | diane@biosynce.com | China | 4871 | 58 | |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131956 | 58 |
| Shanghai Sunway Pharmaceutical Technology Co., Ltd | 13761987713 | hxzheng@sunwaypharm.cn | China | 8666 | 57 |
| Shanghai civi chemical technology co.,Ltd | 86-21-34053660 | sale@labgogo.com | China | 9865 | 52 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| ShangHai AmK Pharmaceutical Technology Co., Ltd. | 微信 17321281695 18019252918 | sale@amkchem.com | China | 14982 | 55 |
| Bellen Chemistry Co., Ltd. | 010-60400365-8001 15910885229 | service@bellenchem.com | China | 4514 | 60 |
879887-32-8(1-Boc-5-formylindoline)Related Search:
1of3
