Cyclopentyl chloroformate
- CAS No.
- 50715-28-1
- Chemical Name:
- Cyclopentyl chloroformate
- Synonyms
- Cyclopentyl carbonochloridate;yclopentyl chloroformate;CYCLOPENTYL CHLOROFORMATE;Cyclopentyl carbonochloridoate;CARBONOCHLORIDIC ACID, CYCLOPENTYL ESTER;Cyclopentyl carbonochloridoate, [(Chlorocarbonyl)oxy]cyclopentane, [(Chloroformyl)oxy]cyclopentane
- CBNumber:
- CB7751594
- Molecular Formula:
- C6H9ClO2
- Molecular Weight:
- 148.59
- MDL Number:
- MFCD00144029
- MOL File:
- 50715-28-1.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Cyclopentyl chloroformate Asreported | 267339 | 50g | $337 |
| Cyclopentyl chloroformate Asreported | 267339 | 100g | $483 |
| Cyclopentyl chloroformate Asreported | 267339 | 250g | $686 |
| Cyclopentyl chloroformate Asreported | 267339 | 500g | $907 |
| Cyclopentyl chloroformate Asreported | 267339 | 1kg | $1244 |
| More product size | |||
| Boiling point | 69.0-70.5 °C(Press: 25 Torr) |
|---|---|
| Density | 1.19±0.1 g/cm3(Predicted) |
| form | liquid |
| color | Brown |
| InChI | InChI=1S/C6H9ClO2/c7-6(8)9-5-3-1-2-4-5/h5H,1-4H2 |
| InChIKey | ZFQCRLNKHHXELH-UHFFFAOYSA-N |
| SMILES | C(Cl)(OC1CCCC1)=O |
| CAS DataBase Reference | 50715-28-1(CAS DataBase Reference) |
| EWG's Food Scores | 1-3 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |    GHS02,GHS05,GHS06 |
|---|---|
| Signal word | Danger |
| Hazard statements | H226-H317-H318-H331 |
| Precautionary statements | P210-P280 |
| Hazard Codes | Xi,T |
| Risk Statements | 10-22-23-41-43-48/22 |
| Safety Statements | 26-36/37/39-45 |
| RIDADR | UN3277 |
| Hazard Note | Irritant |
| HazardClass | 6.1, 8 |
| HS Code | 2916200090 |
| REACH Registrations | Inactive |
| Limited Quantities | 100ml (liquid) or 0.5 Kg (solid) |
| Excepted Quantities | Max Inner Pack (1g or 1ml) and Max Outer Pack (500g or 500ml) |
Cyclopentyl chloroformate price More Price(37)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 267339 | Cyclopentyl chloroformate Asreported | 50715-28-1 | 50g | $337 | 2026-06-03 | Buy |
| Usbiological | 267339 | Cyclopentyl chloroformate Asreported | 50715-28-1 | 100g | $483 | 2026-06-03 | Buy |
| Usbiological | 267339 | Cyclopentyl chloroformate Asreported | 50715-28-1 | 250g | $686 | 2026-06-03 | Buy |
| Usbiological | 267339 | Cyclopentyl chloroformate Asreported | 50715-28-1 | 500g | $907 | 2026-06-03 | Buy |
| Usbiological | 267339 | Cyclopentyl chloroformate Asreported | 50715-28-1 | 1kg | $1244 | 2026-06-03 | Buy |
Cyclopentyl chloroformate Chemical Properties,Uses,Production
Uses
Cyclopentyl Chloroformate is a chemical reagent used in the synthesis of novel peptidomimetic Hep C protease inhibitors.
Synthesis
32315-10-9
96-41-3
50715-28-1
A mixed solution of cyclopentanol (10.9 mL, 120 mmol) and pyridine (10.7 mL, 132 mmol) was added slowly and dropwise to a solution of triphosgene (11.87 g, 40.0 mmol) in anhydrous ether (100 mL) at -70 °C. The reaction mixture was stirred continuously for 1 h at this temperature and then removed from the low temperature bath. Stirring was continued at room temperature for 1.5 h. Subsequently, 1.0 N HCl aqueous solution (110 mL) was added for acidification. The organic phase was separated, washed with brine (60 mL) and dried over anhydrous sodium sulfate. The solvent was removed by distillation under reduced pressure to afford cyclopentyl chloroformate (14.395 g, boiling point 80 °C/75 mmHg, 80.7% yield). The resulting cyclopentyl chloroformate could be used directly in the subsequent reaction without further purification.
References
[1] Patent: CN106045802, 2016, A. Location in patent: Paragraph 0044-0045
[2] Patent: WO2008/95058, 2008, A1. Location in patent: Page/Page column 31
[3] European Journal of Medicinal Chemistry, 1993, vol. 28, # 1, p. 37 - 45
[4] Patent: WO2008/38175, 2008, A2. Location in patent: Page/Page column 38
[5] Patent: CN107417748, 2017, A. Location in patent: Paragraph 0106
Cyclopentyl chloroformate Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Changzhou Fullone Chemical Co., Ltd. | +86-13328197671 +86-13861172460 | sales@borenchem.cn | China | 1055 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21585 | 55 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29812 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 +86-18019713315 | info@accelachem.com | United States | 21193 | 58 |
| Xiamen AmoyChem Co., Ltd | +86-86-5926051114 | sales@amoychem.com | China | 6366 | 58 |
| CONIER CHEM AND PHARMA LIMITED | sales@conier.com | China | 49979 | 58 | |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-87569266 +86-17392581500 | 1015@dideu.com | China | 3861 | 58 |
| SIMAGCHEM CORP | +86-5922680277 +86-13806087780 | sale@simagchem.com | China | 17346 | 58 |
| Hubei Ipure Biology Co., Ltd | +8618062405514 | ada@ipurechemical.com | China | 10236 | 58 |
View Lastest Price from Cyclopentyl chloroformate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2019-07-06 | Cyclopentyl chloroformate
50715-28-1
|
$1.00 | 1kg | 99% | Career Henan Chemical Co |
-
- Cyclopentyl chloroformate
50715-28-1
- $1.00
- 99%
- Career Henan Chemical Co
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