????
|
|
???? ??
- ???
- 243-246 °C (lit.)
- ?? ?
- 355 °C (lit.)
- ??
- 1.1
- ?? ??
- 620kg/m3
- ???
- 400 mm Hg ( 323 °C)
- ???
- 1.6192 (estimate)
- ???
- 220 °C
- ?? ??
- Store below +30°C.
- ???
- ???: ???50mg/mL
- ??? ??
- ??? ??, ???? ?? ???
- ?? ?? (pKa)
- 17.00±0.30(Predicted)
- ??
- ????-??? ?? ????-??
- ???
- 19ºC?? <0.1g/100mL
- Merck
- 14,1790
- BRN
- 3956
- Henry's Law Constant
- 9.4×101 mol/(m3Pa) at 25℃, Brockbank (2013)
- Dielectric constant
- 1.3（Ambient）
- ???
- ????. ?? ??. ?? ???, ????, ?????? ???? ????.
- ?? ??
- ?? ??
??
- InChI
- 1S/C12H9N/c1-3-7-11-9(5-1)10-6-2-4-8-12(10)13-11/h1-8,13H
- InChIKey
- UJOBWOGCFQCDNV-UHFFFAOYSA-N
- SMILES
- c1ccc2c(c1)[nH]c3ccccc23
- LogP
- 3.84 at 22℃ and pH7
- CAS ??????
- 86-74-8(CAS DataBase Reference)
- IARC
- 2B (Vol. 32, Sup 7, 71, 103) 2013
- NIST
- Carbazole(86-74-8)
??
- ?? ? ?? ??
- ?? ? ???? ?? (GHS)
| ??? ?? | Xn,N,T | ||
|---|---|---|---|
| ?? ???? ?? | 22-36/37/38-40-50/53-63-43-23/24/25-45-67-68-51/53 | ||
| ????? | 26-36-60-61-36/37-24/25-23-53-45-36/37/39 | ||
| ????(UN No.) | UN 2811 6.1/PG 3 | ||
| WGK ?? | 2 | ||
| RTECS ?? | FE3150000 | ||
| F ?????? | 10 | ||
| ?? ?? ?? | Harmful | ||
| TSCA | TSCA listed | ||
| ?? ?? | 9 | ||
| ???? | III | ||
| HS ?? | 29339990 | ||
| ???? ??? | 11 - Combustible Solids | ||
| Hazard Classifications | Aquatic Chronic 4 Carc. 2 Muta. 2 |
||
| ?? ?? ??? | 86-74-8(Hazardous Substances Data) | ||
| ?? | LD50 orally in rats: >5 g/kg (Eagle, Carlson) | ||
| ???? ?? | KE-04664 |
???? C??? ??, ??, ??
??
?? ?? ?? ? ?? ? (carbazole) ? ??? ??? ??. ???? ???? ??, ???, ???? ?? ???? ?????, ????, ????? ? ??? ??? ????? ?? ????. ??? ?? ???? ?? ?? ???? ?????. ?? ??? ??, ??, ? ???, ??? ??, ?? ?? ?? ???? ? ??? ? ????. ???? ?? ? ?? ??? ???? RL? ??? ? ?? ? ??? ????? ??? ?? ?????. ??? ?? ?? ??? ??? ??? ??? ????. Carbazole? ? ?? ??? RNX, ?? ?? ?? FFRL, FFGL ?? ???? ? ?????. ??, N- ?? ?? ? ????, ??? ??? ?? ?, ?? ? ????? ? UV- ??? ?? ?? ??? ?? ??? ???? ?? ? ????.??
?? ??? ?? ?? ? ?? ?????. ????? ?? ????? ???? ?? ? ?????. ???? ?? ??? 90 %? ?? ???? ????. ?? ?? ??, ??, ? ???, ??? ??, ?? ?? ?? ??? ??? ? ????. ??? ? ??? ? ?? ?? ???? ?? ?????. ????? ??? ???? ??? ???? ?????. ? ??? ?? ?? ? RNX? Haichang blue? ??? ??? ?????. ?? ?? ?? ?? ???? ?????. ?? ??? ?? ? IDM, ?? ? LR, ?? ? LB ? ?? ? L3B?? ?? ? ??? ?? ? ?? D???. ?? ? ? ?? ? ????? ??, ?? ??, ??? ?? ???? ?? ? ??? ?????. ?? ?? ?? RNX, ???? ?? FFRL, FFGL ?? ????? ?????. ? ??? ??, N- ?? ?? ? ????, ??? ??? ?? ? ? ?? ?? ??? ?? ??? ???? ???? ? ??? ? ??? UV ??? ?? ??? ???? ??? ??? ? ????.??? ??
white crystals or light brown powder??
Carbazole and its derivatives are widely used as an intermediate in synthesis of pharmaceuticals, agrochemicals, dyes, pigments and other organic compounds.carbazole is also used in luminescence chemistry as a photosensitizing and additional charge transport material. Carbazole structure is a motif in pharmaceuticals such as carvedilol used to treat high blood pressure and to prevent cardiac arrhythmias and angina.??
carbazole: A white crystalline compoundfound with anthracene,C12H9N; m.p. 238°C; b.p. 335°C. It isused in the manufacture of dyestuffs.?? ??
White crystals, plates, leaflets or light tan powder. Sublimes readily. Exhibits strong fluorescence and long phosphorescence on exposure to ultraviolet light.??? ?? ??
Insoluble in water.?? ???
Carbazole is an extremely weak base. Carbazole is incompatible with strong oxidizing agents. Carbazole reacts with nitrogen oxides. Potassium hydroxide fusion yields a salt.???
Possible carcinogen.????
Flash point data for Carbazole are not available; however, Carbazole is probably combustible.Safety Profile
intraperitoneal route. A flammable liquid.Purification Methods
Dissolve carbazole (60g) in conc H2SO4 (300mL), extract with three 200mL portions of *benzene, then stir this into 1600mL of an ice-water mixture. The precipitate is filtered off, washed with a little water, dried, recrystallised from *benzene and then from pyridine/*benzene [Feldman et al. J Am Chem Soc 73 4341 1951]. It has also been recrystallised from EtOH or toluene, sublimed in vacuum, zone-refined, and purified by TLC. [UV: Armarego in Physical Methods in Heterocyclic Chemistry (Ed Katritzky, Academic Press) Vol III 158 1971, Beilstein 20/8 V 9.]???? ?? ?? ? ???
???
UP? ??? ???
Fine
N-????????97
2-???????(2-AMINOBIPHENYL)
Anthracene oil
??? ???
Separating equipment
????
????
[1,1'-Biphenyl]-2-amine, 2'-chloro-
?? ??
9-(3-(CIS-3 5-DIMETHYL-1-PIPERAZINYL)-
2-Hydroxy-N-(4-methoxyphenyl)-11H-benzo[a]carbazole-3-carboxamide
3-Amino-9-ethylcarbazole
Vat Blue 43
N-(4-?????)-2-????-9H-????-3-??????
9-?????
9-??-3-nitrocarbazole
????
3-(9-CARBAZOLYL)PROPIONIC ACID
????? ???? ????
9H-Carbazole, 1,6-dichloro-
Sulphur Indanthrene Blue RNX
????
1-??????
3-Bromo-9H-carbazole
3-tert-??-9H-???
3-(9H-????-9-?)?????
9-Phenylcarbazole
TIMTEC-BB SBB006353
???? ?? ??
???( 419)?? ??
| ??? | ?? | ??? | ?? | ?? ? | ?? |
|---|---|---|---|---|---|
| Henan Allgreen Chemical Co.,LTD | +86-37155567971 +86-13633837469 |
info@allgreenchem.com | China | 6000 | 58 |
| Changyi Longchang Bio-Chemical Co., LTD | +86-13256193735; +86-13256193735 |
info@longchangchemical.com | China | 1044 | 58 |
| SHANGHAI KEAN TECHNOLOGY CO., LTD. | +8613817748580 |
cooperation@kean-chem.com | China | 40066 | 58 |
| Fuxin Pharmaceutical | +86-021-021-50872116 |
contact@fuxinpharm.com | China | 9976 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +86-15350571055 |
Sibel@chuanghaibio.com | China | 8738 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 |
sales@capot.com | China | 29640 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21585 | 55 |
| Shanghai Time Chemicals CO., Ltd. | +86-021-57951555 +8618017249410 |
jack.li@time-chemicals.com | China | 1803 | 55 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 33024 | 60 |
| Speranza Chemical Co., Ltd. | +86-86-075521030354 +86-18688942810 |
sophieliu@speranzachem.com | China | 923 | 55 |
???? ?? ??:
4-??????? 4,4'-??????? 4,4'-??????? ???? ??? ? ????? ??? ?? ????
beta-Methyl vinyl phosphate (MAP)
Furo[3,4-b]pyridin-5(7H)-one
ELLIPTICINE
3-Amino-9-ethylcarbazole
1,2,3,4-Tetrahydrocarbazole
tert-Butyl carbazate
1,2,3,4-Tetrahydro-9-methylcarbazol-4-one
4-Epoxypropanoxycarbazole
Carprofen
9-[3-(CIS-3,5-DIMETHYL-1-PIPERAZINYL)PROPYL]-9H-CARBAZOLE DIHYDROCHLORIDE