GSK J1
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GSK J1 ??
- ?? ?
- 608.9±55.0 °C(Predicted)
- ??
- 1.292±0.06 g/cm3(Predicted)
- ?? ??
- 2-8°C
- ???
- DMSO: ???15mg/mL, ??
- ??? ??
- ??
- ?? ?? (pKa)
- 4.20±0.10(Predicted)
- ??
- ???? ????
- ???
- ?? 3?? ?? -20°? DMSO? ?? ??
- InChI
- 1S/C22H23N5O2/c28-21(29)8-12-24-19-15-20(26-22(25-19)18-7-3-4-11-23-18)27-13-9-16-5-1-2-6-17(16)10-14-27/h1-7,11,15H,8-10,12-14H2,(H,28,29)(H,24,25,26)
- InChIKey
- AVZCPICCWKMZDT-UHFFFAOYSA-N
- SMILES
- OC(CCNC1=CC(N2CCC(C=CC=C3)=C3CC2)=NC(C4=CC=CC=N4)=N1)=O
??
- ?? ? ?? ??
- ?? ? ???? ?? (GHS)
| ????(GHS): |
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| ??·?? ??: |
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| ??????: |
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GSK J1 C??? ??, ??, ??
??
GSK J1 is a selective and potent inhibitor of JMJDE and UTX demethylases.Biochem/physiol Actions
GSK-J1 is also termed as 3-((6-(4,5-Dihydro-1H-benzo[d]azepin-3(2H)-yl)-2-(pyridin-2-yl)pyrimidin-4-yl)amino)propanoate. It may disturb the differentiation of specific neuronal subtypes in growing rat retina.GSK J1 ?? ?? ? ???
???
2,3,4,5-TETRAHYDRO-1H-BENZO[D]AZEPINE
4,6-DICHLORO-2-(2-PYRIDINYL)PYRIMIDINE
???? ?????
N,N-????????????
?? ??
GSK J1 ?? ??
???( 123)?? ??
| ??? | ?? | ??? | ?? | ?? ? | ?? |
|---|---|---|---|---|---|
| Shaanxi Haibo Biotechnology Co., Ltd | +undefined18602966907 |
qinhe02@xaltbio.com | China | 997 | 58 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 33024 | 60 |
| Biochempartner | 0086-13720134139 |
candy@biochempartner.com | CHINA | 965 | 58 |
| BOC Sciences | +1-631-485-4226 |
inquiry@bocsci.com | United States | 19936 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 |
factory@coreychem.com | China | 29792 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 |
marketing@targetmol.com | United States | 32467 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 |
laboratory@coreychem.com | China | 30224 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 |
sales@hzclap.com | CHINA | 6312 | 58 |
| Chemia Biotechnology（Shanghai） Co., Ltd | +8613816753574 |
info@chemia-pharm.com | CHINA | 311 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471; |
sales@sarms4muscle.com | China | 10473 | 58 |
GSK J1 ?? ??:
SIRTINOL
Resveratrol
2-N-HEXYL-4-PENTYNOIC ACID
Entinostat
2-Cyanopyridine
Entospletinib (GS-9973)
GS9620
GSK2643943A
GS967
GSK-114
GSK-626616
3-[[[2-Methoxy-4-(phenylamino)phenyl]amino]sulfonyl]-2-thiophenecarboxylicacidmethylester
Selonsertib
Presatovir
4-HYDROXY-2-[(1E)-[4-(1-METHYLETHYL)PHENYL]METHYLENE]HYDRAZIDE
GSK J4 HCl
GSK J5
GSK J2