4-[2-(2-methylphenyl)ethynyl]-benzenepropanoicacid
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- $37 - $2221.5
- Product name: 4-[2-(2-methylphenyl)ethynyl]-benzenepropanoicacid
- CAS: 1082058-99-8
- MF: C18H16O2
- MW: 264.32
- EINECS:
- MDL Number:MFCD12912449
- Synonyms:4-[2-(2-methylphenyl)ethynyl]-benzenepropanoicacid;TUG 424;CAY10587;3-(4-(o-Tolylethynyl)phenyl)propanoic acid;FODHWOBAQBTTFS-UHFFFAOYSA-N;TUG-424 >=98% (HPLC);3-(4-(o-Tolylethynyl)phenyl)propanoic acid , TUG-424;TUG-424, 10 mM in DMSO
41 prices
Selected condition:
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Biorbyt Ltd
- Biosynth
- Cayman Chemical
- ChemScene
- Sigma-Aldrich
Package
- 5mg
- 10mg
- 10mM*1mLinDMSO(Solid+Solvent)
- 1mg
- 1mlx10mM(inDMSO)
- 10mM*1mLinDMSO(Solution)
- 25mg
- 50mg
- 100mg
- 250MG
- 500mg
- Manufactureraablocks
- Product numberAA007D68
- Product description3-(4-(O-Tolylethynyl)Phenyl)Propanoic Acid ≥98.0%
- Packaging25mg
- Price$222
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA007D68
- Product description3-(4-(O-Tolylethynyl)Phenyl)Propanoic Acid ≥98.0%
- Packaging50mg
- Price$401
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA007D68
- Product description3-(4-(O-Tolylethynyl)Phenyl)Propanoic Acid ≥98.0%
- Packaging100mg
- Price$720
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA007D68
- Product description3-(4-(O-Tolylethynyl)Phenyl)Propanoic Acid ≥98.0%
- Packaging10mg
- Price$102
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA007D68
- Product description3-(4-(O-Tolylethynyl)Phenyl)Propanoic Acid ≥98.0%
- Packaging5mg
- Price$57
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA007D68
- Product description3-(4-(O-Tolylethynyl)Phenyl)Propanoic Acid ≥98%
- Packaging1mg
- Price$37
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberY225345
- Product description4-[2-(2-methylphenyl)ethynyl]-benzenepropanoicacid 95.00%
- Packaging250MG
- Price$1485
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberY225345
- Product description4-[2-(2-methylphenyl)ethynyl]-benzenepropanoicacid 95.00%
- Packaging100MG
- Price$815
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product number8587BB
- Product description3-(4-(o-Tolylethynyl)phenyl)propanoicacid
- Packaging25mg
- Price$714
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number8587BB
- Product description3-(4-(o-Tolylethynyl)phenyl)propanoicacid
- Packaging10mg
- Price$380
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberLIP0000535
- Product descriptionTUG-424 95.00%
- Packaging5MG
- Price$715.3
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberLIP0000535
- Product descriptionTUG-424 95.00%
- Packaging1MG
- Price$576.06
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberLIP0000535
- Product descriptionTUG-424 95.00%
- Packaging25MG
- Price$1076.92
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7499
- Product descriptionTUG 424
- Packaging10mg
- Price$420
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB7499
- Product descriptionTUG 424
- Packaging25mg
- Price$840
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB7499
- Product descriptionTUG 424
- Packaging5mg
- Price$279
- Updated2026-05-06
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA007D68 | 3-(4-(O-Tolylethynyl)Phenyl)Propanoic Acid ≥98.0% | 25mg | $222 | 2026-05-28 | Buy |
| aablocks | AA007D68 | 3-(4-(O-Tolylethynyl)Phenyl)Propanoic Acid ≥98.0% | 50mg | $401 | 2026-05-28 | Buy |
| aablocks | AA007D68 | 3-(4-(O-Tolylethynyl)Phenyl)Propanoic Acid ≥98.0% | 100mg | $720 | 2026-05-28 | Buy |
| aablocks | AA007D68 | 3-(4-(O-Tolylethynyl)Phenyl)Propanoic Acid ≥98.0% | 10mg | $102 | 2026-05-28 | Buy |
| aablocks | AA007D68 | 3-(4-(O-Tolylethynyl)Phenyl)Propanoic Acid ≥98.0% | 5mg | $57 | 2026-05-28 | Buy |
| aablocks | AA007D68 | 3-(4-(O-Tolylethynyl)Phenyl)Propanoic Acid ≥98% | 1mg | $37 | 2026-05-28 | Buy |
| ACHEMBLOCK | Y225345 | 4-[2-(2-methylphenyl)ethynyl]-benzenepropanoicacid 95.00% | 250MG | $1485 | 2026-05-27 | Buy |
| ACHEMBLOCK | Y225345 | 4-[2-(2-methylphenyl)ethynyl]-benzenepropanoicacid 95.00% | 100MG | $815 | 2026-05-27 | Buy |
| AK Scientific | 8587BB | 3-(4-(o-Tolylethynyl)phenyl)propanoicacid | 25mg | $714 | 2021-12-16 | Buy |
| AK Scientific | 8587BB | 3-(4-(o-Tolylethynyl)phenyl)propanoicacid | 10mg | $380 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | LIP0000535 | TUG-424 95.00% | 5MG | $715.3 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | LIP0000535 | TUG-424 95.00% | 1MG | $576.06 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | LIP0000535 | TUG-424 95.00% | 25MG | $1076.92 | 2021-12-16 | Buy |
| ApexBio Technology | B7499 | TUG 424 | 10mg | $420 | 2026-05-06 | Buy |
| ApexBio Technology | B7499 | TUG 424 | 25mg | $840 | 2026-05-06 | Buy |
| ApexBio Technology | B7499 | TUG 424 | 5mg | $279 | 2026-05-06 | Buy |
Properties
Boiling point :448.1±38.0 °C(Predicted)
Density :1.17±0.1 g/cm3(Predicted)
storage temp. :Store at +4°C
solubility :DMSO: >10mg/mL
pka :4.62±0.10(Predicted)
form :A crystalline solid
color :White to off-white
InChI :1S/C18H16O2/c1-14-4-2-3-5-17(14)12-10-15-6-8-16(9-7-15)11-13-18(19)20/h2-9H,11,13H2,1H3,(H,19,20)
InChIKey :FODHWOBAQBTTFS-UHFFFAOYSA-N
SMILES :Cc1ccccc1C#Cc2ccc(CCC(O)=O)cc2
Density :1.17±0.1 g/cm3(Predicted)
storage temp. :Store at +4°C
solubility :DMSO: >10mg/mL
pka :4.62±0.10(Predicted)
form :A crystalline solid
color :White to off-white
InChI :1S/C18H16O2/c1-14-4-2-3-5-17(14)12-10-15-6-8-16(9-7-15)11-13-18(19)20/h2-9H,11,13H2,1H3,(H,19,20)
InChIKey :FODHWOBAQBTTFS-UHFFFAOYSA-N
SMILES :Cc1ccccc1C#Cc2ccc(CCC(O)=O)cc2
Safety Information
| Symbol(GHS): |
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| Signal word: | Warning | |||||||||||||||||||||
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Description
The free fatty acid receptor 1 (FFAR1; GPR40) is highly expressed in pancreatic β-cells and activated by medium and long-chain fatty acids. There is evidence of a link between FFAR1 (GPR40) and the ability of fatty acids to amplify glucose-stimulated insulin secretion, making this signaling pathway a potential target for regulating diabetes, obesity, and other metabolic disorders. CAY10587 is a selective FFAR1 (GPR40) agonist (EC50 = 32 nM) that does not exhibit activity on the related FFARs: FFAR2 (GPR43) or FFAR3 (GPR41). At 100 nM, CAY10587 increases glucose-stimulated insulin secretion in the rat insulin-secreting cell line INS-1E.Suppliers and manufacturers
Shanghai Scibiotron Pharmaceutical Co., Ltd
SHANGHAI YOUNG-CHEM CHEMICAL CO., LTD.
3B Pharmachem (Wuhan) International Co.,Ltd.
Shanghai HuanChuan Industry Co.,Ltd.
EMMX Biotechnology LLC
Shanghai YuanYe Biotechnology Co., Ltd.
MQ (shanghai) Pharmaceuticals Co., Ltd.
SHANGHAI FDC-CHEMICAL CO.,LTD
ChemeGen(Shanghai) Biotechnology Co.,Ltd.





