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ChemicalBook >> CAS DataBase List >> 4-[2-(2-methylphenyl)ethynyl]-benzenepropanoicacid

4-[2-(2-methylphenyl)ethynyl]-benzenepropanoicacid

4-[2-(2-methylphenyl)ethynyl]-benzenepropanoicacid price.
  • $37 - $2221.5
  • Product name: 4-[2-(2-methylphenyl)ethynyl]-benzenepropanoicacid
  • CAS: 1082058-99-8
  • MF: C18H16O2
  • MW: 264.32
  • EINECS:
  • MDL Number:MFCD12912449
  • Synonyms:4-[2-(2-methylphenyl)ethynyl]-benzenepropanoicacid;TUG 424;CAY10587;3-(4-(o-Tolylethynyl)phenyl)propanoic acid;FODHWOBAQBTTFS-UHFFFAOYSA-N;TUG-424 >=98% (HPLC);3-(4-(o-Tolylethynyl)phenyl)propanoic acid , TUG-424;TUG-424, 10 mM in DMSO
41 prices
Selected condition:
Brand
  • aablocks
  • ACHEMBLOCK
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • Biorbyt Ltd
  • Biosynth
  • Cayman Chemical
  • ChemScene
  • Sigma-Aldrich
Package
  • 5mg
  • 10mg
  • 10mM*1mLinDMSO(Solid+Solvent)
  • 1mg
  • 1mlx10mM(inDMSO)
  • 10mM*1mLinDMSO(Solution)
  • 25mg
  • 50mg
  • 100mg
  • 250MG
  • 500mg
  • Manufactureraablocks
  • Product numberAA007D68
  • Product description3-(4-(O-Tolylethynyl)Phenyl)Propanoic Acid ≥98.0%
  • Packaging25mg
  • Price$222
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA007D68
  • Product description3-(4-(O-Tolylethynyl)Phenyl)Propanoic Acid ≥98.0%
  • Packaging50mg
  • Price$401
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA007D68
  • Product description3-(4-(O-Tolylethynyl)Phenyl)Propanoic Acid ≥98.0%
  • Packaging100mg
  • Price$720
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA007D68
  • Product description3-(4-(O-Tolylethynyl)Phenyl)Propanoic Acid ≥98.0%
  • Packaging10mg
  • Price$102
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA007D68
  • Product description3-(4-(O-Tolylethynyl)Phenyl)Propanoic Acid ≥98.0%
  • Packaging5mg
  • Price$57
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA007D68
  • Product description3-(4-(O-Tolylethynyl)Phenyl)Propanoic Acid ≥98%
  • Packaging1mg
  • Price$37
  • Updated2026-05-28
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberY225345
  • Product description4-[2-(2-methylphenyl)ethynyl]-benzenepropanoicacid 95.00%
  • Packaging250MG
  • Price$1485
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberY225345
  • Product description4-[2-(2-methylphenyl)ethynyl]-benzenepropanoicacid 95.00%
  • Packaging100MG
  • Price$815
  • Updated2026-05-27
  • Buy
  • ManufacturerAK Scientific
  • Product number8587BB
  • Product description3-(4-(o-Tolylethynyl)phenyl)propanoicacid
  • Packaging25mg
  • Price$714
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number8587BB
  • Product description3-(4-(o-Tolylethynyl)phenyl)propanoicacid
  • Packaging10mg
  • Price$380
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberLIP0000535
  • Product descriptionTUG-424 95.00%
  • Packaging5MG
  • Price$715.3
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberLIP0000535
  • Product descriptionTUG-424 95.00%
  • Packaging1MG
  • Price$576.06
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberLIP0000535
  • Product descriptionTUG-424 95.00%
  • Packaging25MG
  • Price$1076.92
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7499
  • Product descriptionTUG 424
  • Packaging10mg
  • Price$420
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7499
  • Product descriptionTUG 424
  • Packaging25mg
  • Price$840
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7499
  • Product descriptionTUG 424
  • Packaging5mg
  • Price$279
  • Updated2026-05-06
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA007D68 3-(4-(O-Tolylethynyl)Phenyl)Propanoic Acid ≥98.0% 25mg $222 2026-05-28 Buy
aablocks AA007D68 3-(4-(O-Tolylethynyl)Phenyl)Propanoic Acid ≥98.0% 50mg $401 2026-05-28 Buy
aablocks AA007D68 3-(4-(O-Tolylethynyl)Phenyl)Propanoic Acid ≥98.0% 100mg $720 2026-05-28 Buy
aablocks AA007D68 3-(4-(O-Tolylethynyl)Phenyl)Propanoic Acid ≥98.0% 10mg $102 2026-05-28 Buy
aablocks AA007D68 3-(4-(O-Tolylethynyl)Phenyl)Propanoic Acid ≥98.0% 5mg $57 2026-05-28 Buy
aablocks AA007D68 3-(4-(O-Tolylethynyl)Phenyl)Propanoic Acid ≥98% 1mg $37 2026-05-28 Buy
ACHEMBLOCK Y225345 4-[2-(2-methylphenyl)ethynyl]-benzenepropanoicacid 95.00% 250MG $1485 2026-05-27 Buy
ACHEMBLOCK Y225345 4-[2-(2-methylphenyl)ethynyl]-benzenepropanoicacid 95.00% 100MG $815 2026-05-27 Buy
AK Scientific 8587BB 3-(4-(o-Tolylethynyl)phenyl)propanoicacid 25mg $714 2021-12-16 Buy
AK Scientific 8587BB 3-(4-(o-Tolylethynyl)phenyl)propanoicacid 10mg $380 2021-12-16 Buy
American Custom Chemicals Corporation LIP0000535 TUG-424 95.00% 5MG $715.3 2021-12-16 Buy
American Custom Chemicals Corporation LIP0000535 TUG-424 95.00% 1MG $576.06 2021-12-16 Buy
American Custom Chemicals Corporation LIP0000535 TUG-424 95.00% 25MG $1076.92 2021-12-16 Buy
ApexBio Technology B7499 TUG 424 10mg $420 2026-05-06 Buy
ApexBio Technology B7499 TUG 424 25mg $840 2026-05-06 Buy
ApexBio Technology B7499 TUG 424 5mg $279 2026-05-06 Buy

Properties

Boiling point :448.1±38.0 °C(Predicted)
Density :1.17±0.1 g/cm3(Predicted)
storage temp. :Store at +4°C
solubility :DMSO: >10mg/mL
pka :4.62±0.10(Predicted)
form :A crystalline solid
color :White to off-white
InChI :1S/C18H16O2/c1-14-4-2-3-5-17(14)12-10-15-6-8-16(9-7-15)11-13-18(19)20/h2-9H,11,13H2,1H3,(H,19,20)
InChIKey :FODHWOBAQBTTFS-UHFFFAOYSA-N
SMILES :Cc1ccccc1C#Cc2ccc(CCC(O)=O)cc2

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)Environment (GHS09)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H410 Very toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 1 Warning P273, P391, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P391 Collect spillage. Hazardous to the aquatic environment

Description

The free fatty acid receptor 1 (FFAR1; GPR40) is highly expressed in pancreatic β-cells and activated by medium and long-chain fatty acids. There is evidence of a link between FFAR1 (GPR40) and the ability of fatty acids to amplify glucose-stimulated insulin secretion, making this signaling pathway a potential target for regulating diabetes, obesity, and other metabolic disorders. CAY10587 is a selective FFAR1 (GPR40) agonist (EC50 = 32 nM) that does not exhibit activity on the related FFARs: FFAR2 (GPR43) or FFAR3 (GPR41). At 100 nM, CAY10587 increases glucose-stimulated insulin secretion in the rat insulin-secreting cell line INS-1E.

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