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ChemicalBook >> CAS DataBase List >> [(3R)-3-(Hydroxymethyl)-1-piperidinyl][4-[2-(4-methoxyphenyl)ethynyl]phenyl]-methanone

[(3R)-3-(Hydroxymethyl)-1-piperidinyl][4-[2-(4-methoxyphenyl)ethynyl]phenyl]-methanone

[(3R)-3-(Hydroxymethyl)-1-piperidinyl][4-[2-(4-methoxyphenyl)ethynyl]phenyl]-methanone price.
  • $37 - $2031
  • Product name: [(3R)-3-(Hydroxymethyl)-1-piperidinyl][4-[2-(4-methoxyphenyl)ethynyl]phenyl]-methanone
  • CAS: 1382481-79-9
  • MF: C22H23NO3
  • MW: 349.42
  • EINECS:802-823-8
  • MDL Number:MFCD25541754
  • Synonyms:[(3R)-3-(Hydroxymethyl)-1-piperidinyl][4-[2-(4-methoxyphenyl)ethynyl]phenyl]-methanone;ML289;VU0463597;[(3R)-3-(hydroxymethyl)piperidin-1-yl]-[4-[2-(4-methoxyphenyl)ethynyl]phenyl]methanone;[(3R)-3-(Hydroxymethyl)-1-pipridinyl][4-[2-(4-methoxyphenyl)ethynyl]phenyl]methanone;Methanone, [(3R)-3-(hydroxymethyl)-1-piperidinyl][4-[2-(4-methoxyphenyl)ethynyl]phenyl]-;(3R)-3-(Hydroxymethyl)-1-piperidinyl]{4-[(4-methoxyphenyl)ethyny l]phenyl}methanone;ML289, 10 mM in DMSO
40 prices
Selected condition:
Brand
  • aablocks
  • ACHEMBLOCK
  • AK Scientific
  • ApexBio Technology
  • Arctom
  • Cayman Chemical
  • DC Chemicals
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 10
  • 1mg
  • 5mg
  • 50
  • 10mg
  • 25mg
  • 50mg
  • 10mM*1mLinDMSO(Solution)
  • 10mM*1mLinDMSO(Solid+Solvent)
  • 100mg
  • 250mg
  • 1g
  • Manufactureraablocks
  • Product numberAA00AAV2
  • Product descriptionML-289 ≥98%
  • Packaging1mg
  • Price$41
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00AAV2
  • Product descriptionML-289 ≥98%
  • Packaging5mg
  • Price$99
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00AAV2
  • Product descriptionML-289
  • Packaging10mg
  • Price$180
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00AAV2
  • Product descriptionML-289
  • Packaging25mg
  • Price$331
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00AAV2
  • Product descriptionML-289
  • Packaging50mg
  • Price$533
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00AAV2
  • Product descriptionML-289
  • Packaging100mg
  • Price$889
  • Updated2026-05-28
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberY227367
  • Product descriptionML289 97.00%
  • Packaging100MG
  • Price$425
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberY227367
  • Product descriptionML289 97.00%
  • Packaging50MG
  • Price$280
  • Updated2026-05-27
  • Buy
  • ManufacturerAK Scientific
  • Product numberSYN5346
  • Product descriptionML289
  • Packaging10mg
  • Price$160
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number7624DM
  • Product description[(3R)-3-(Hydroxymethyl)piperidin-1-yl]-[4-[2-(4-methoxyphenyl)ethynyl]phenyl]methanone
  • Packaging1mg
  • Price$139
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberSYN5346
  • Product descriptionML289
  • Packaging100mg
  • Price$931
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB5783
  • Product descriptionML 289
  • Packaging50mg
  • Price$2031
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB5783
  • Product descriptionML 289
  • Packaging10mg
  • Price$211
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB5783
  • Product descriptionML289
  • Packaging10mg
  • Price$245
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB5783
  • Product descriptionML 289
  • Packaging1mg
  • Price$50
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB5783
  • Product descriptionML 289
  • Packaging5mg
  • Price$132
  • Updated2026-05-06
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA00AAV2 ML-289 ≥98% 1mg $41 2026-05-28 Buy
aablocks AA00AAV2 ML-289 ≥98% 5mg $99 2026-05-28 Buy
aablocks AA00AAV2 ML-289 10mg $180 2026-05-28 Buy
aablocks AA00AAV2 ML-289 25mg $331 2026-05-28 Buy
aablocks AA00AAV2 ML-289 50mg $533 2026-05-28 Buy
aablocks AA00AAV2 ML-289 100mg $889 2026-05-28 Buy
ACHEMBLOCK Y227367 ML289 97.00% 100MG $425 2026-05-27 Buy
ACHEMBLOCK Y227367 ML289 97.00% 50MG $280 2026-05-27 Buy
AK Scientific SYN5346 ML289 10mg $160 2021-12-16 Buy
AK Scientific 7624DM [(3R)-3-(Hydroxymethyl)piperidin-1-yl]-[4-[2-(4-methoxyphenyl)ethynyl]phenyl]methanone 1mg $139 2021-12-16 Buy
AK Scientific SYN5346 ML289 100mg $931 2021-12-16 Buy
ApexBio Technology B5783 ML 289 50mg $2031 2026-05-06 Buy
ApexBio Technology B5783 ML 289 10mg $211 2026-05-06 Buy
ApexBio Technology B5783 ML289 10mg $245 2021-12-16 Buy
ApexBio Technology B5783 ML 289 1mg $50 2026-05-06 Buy
ApexBio Technology B5783 ML 289 5mg $132 2026-05-06 Buy

Properties

storage temp. :2-8°C
solubility :DMSO: soluble10mg/mL, clear
form :powder
color :white to beige

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Glutamate, the major excitatory neurotransmitter in the CNS, activates eight known subtypes of metabotropic glutamate receptors (mGluRs). Highly selective modulators designed to act at allosteric sites within the receptor are being developed to preferentially target individual mGluR subtypes in order to determine their distinct pharmacological roles. ML-298 is a negative allosteric modulator of mGlu3 (IC50 = 0.66 μM) that displays 15-fold selectivity over mGlu2 and inactivity against mGlu5.

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