ACTINONIN
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- $44 - $4350
- Product name: ACTINONIN
- CAS: 13434-13-4
- MF: C19H35N3O5
- MW: 385.5
- EINECS:
- MDL Number:MFCD00058569
- Synonyms:(-)-ACTINONIN;3-[[1-[[2-(HYDROXYMETHYL)-1-PYRROLIDINYL]CARBONYL]-2-METHYL-PROPYL]CARBAMOYL]OCTANOHYDROXAMIC ACID;3-[[1-[[2-(HYDROXYMETHYL)-1-PYRROLIDINYL]-CARBONYL]-2-METHYLPROPYL]-CARBAMOYL]-OCTONOHYDROXAMIC ACID;N4-HYDROXY-N1-[(1S)-1[[(2S)-2-(HYDROXYMETHYL)-1-PYRROLDINYL]CARBONYL]-2-METHYLPROPYL]-2-PENTYL-,(2R)-(9CI);hylpropyl)carbamoyl)- ;octanohydroxamicacid,3-((1-((2-(hydroxymethyl)-1-pyrrolidinyl)carbonyl)-2-met ;N'-Hydroxy-N-[1-[[2-(hydroxymethyl)-1-pyrrolidinyl]carbonyl]-2-methylpropyl]-2-pentylbutanediamide;(2R)-2-[2-(hydroxyamino)-2-keto-ethyl]-N-[(1S)-2-methyl-1-[(2S)-2-methylolpyrrolidine-1-carbonyl]propyl]enanthamide
55 prices
Selected condition:
Brand
- aablocks
- Adipogen Life Sciences
- Ambeed
- ApexBio Technology
- Arctom
- AvaChem
- Biorbyt Ltd
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TRC
- Usbiological
Package
- 2mg
- 2.5mg
- 1mg
- 1mlx10mM(inDMSO)
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- Manufactureraablocks
- Product numberAA007ZY4
- Product descriptionActinonin 95%
- Packaging1mg
- Price$44
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA007ZY4
- Product descriptionActinonin 95%
- Packaging5mg
- Price$53
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA007ZY4
- Product descriptionActinonin 95%
- Packaging10mg
- Price$95
- Updated2026-05-28
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CN2-0161-M005
- Product descriptionActinonin >97.0%(HPLC)
- Packaging5mg
- Price$98
- Updated2021-12-16
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CN2-0161-M005
- Product descriptionActinonin >97.0%(HPLC)
- Packaging5mg
- Price$95
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CN2-0161-M025
- Product descriptionActinonin >97.0%(HPLC)
- Packaging25mg
- Price$380
- Updated2026-05-06
- Buy
- ManufacturerAmbeed
- Product numberA236595
- Product descriptionActinonin 95%
- Packaging1mg
- Price$76
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC3331
- Product descriptionActinonin
- Packaging5mg
- Price$121
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC3331
- Product descriptionActinonin
- Packaging25mg
- Price$516
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberBD-A236595
- Product descriptionActinonin 95%
- Packaging50mg
- Price$369
- Updated2026-05-25
- Buy
- ManufacturerArctom
- Product numberBD-A236595
- Product descriptionActinonin 95%
- Packaging50mg
- Price$369
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberBD-A236595
- Product descriptionActinonin 95%
- Packaging25mg
- Price$206
- Updated2026-05-25
- Buy
- ManufacturerArctom
- Product numberBD-A236595
- Product descriptionActinonin 95%
- Packaging25mg
- Price$206
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberBD-A236595
- Product descriptionActinonin 95%
- Packaging10mg
- Price$98
- Updated2026-05-25
- Buy
- ManufacturerArctom
- Product numberBD-A236595
- Product descriptionActinonin 95%
- Packaging10mg
- Price$98
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberBD-A236595
- Product descriptionActinonin 95%
- Packaging5mg
- Price$55
- Updated2026-05-25
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA007ZY4 | Actinonin 95% | 1mg | $44 | 2026-05-28 | Buy |
| aablocks | AA007ZY4 | Actinonin 95% | 5mg | $53 | 2026-05-28 | Buy |
| aablocks | AA007ZY4 | Actinonin 95% | 10mg | $95 | 2026-05-28 | Buy |
| Adipogen Life Sciences | AG-CN2-0161-M005 | Actinonin >97.0%(HPLC) | 5mg | $98 | 2021-12-16 | Buy |
| Adipogen Life Sciences | AG-CN2-0161-M005 | Actinonin >97.0%(HPLC) | 5mg | $95 | 2026-05-06 | Buy |
| Adipogen Life Sciences | AG-CN2-0161-M025 | Actinonin >97.0%(HPLC) | 25mg | $380 | 2026-05-06 | Buy |
| Ambeed | A236595 | Actinonin 95% | 1mg | $76 | 2021-12-16 | Buy |
| ApexBio Technology | C3331 | Actinonin | 5mg | $121 | 2021-12-16 | Buy |
| ApexBio Technology | C3331 | Actinonin | 25mg | $516 | 2021-12-16 | Buy |
| Arctom | BD-A236595 | Actinonin 95% | 50mg | $369 | 2026-05-25 | Buy |
| Arctom | BD-A236595 | Actinonin 95% | 50mg | $369 | 2026-05-26 | Buy |
| Arctom | BD-A236595 | Actinonin 95% | 25mg | $206 | 2026-05-25 | Buy |
| Arctom | BD-A236595 | Actinonin 95% | 25mg | $206 | 2026-05-26 | Buy |
| Arctom | BD-A236595 | Actinonin 95% | 10mg | $98 | 2026-05-25 | Buy |
| Arctom | BD-A236595 | Actinonin 95% | 10mg | $98 | 2026-05-26 | Buy |
| Arctom | BD-A236595 | Actinonin 95% | 5mg | $55 | 2026-05-25 | Buy |
Properties
Melting point :137-139°C
Density :1.139±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 20 mg/ml).
pka :9.19±0.20(Predicted)
form :White to off-white powder.
color :White
biological source :synthetic (organic)
BRN :1555250
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 2 months.
InChI :1S/C19H35N3O5/c1-4-5-6-8-14(11-16(24)21-27)18(25)20-17(13(2)3)19(26)22-10-7-9-15(22)12-23/h13-15,17,23,27H,4-12H2,1-3H3,(H,20,25)(H,21,24)
InChIKey :XJLATMLVMSFZBN-UHFFFAOYSA-N
SMILES :CCCCCC(CC(=O)NO)C(=O)NC(C(C)C)C(=O)N1CCCC1CO
CAS DataBase Reference :13434-13-4(CAS DataBase Reference)
Density :1.139±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 20 mg/ml).
pka :9.19±0.20(Predicted)
form :White to off-white powder.
color :White
biological source :synthetic (organic)
BRN :1555250
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 2 months.
InChI :1S/C19H35N3O5/c1-4-5-6-8-14(11-16(24)21-27)18(25)20-17(13(2)3)19(26)22-10-7-9-15(22)12-23/h13-15,17,23,27H,4-12H2,1-3H3,(H,20,25)(H,21,24)
InChIKey :XJLATMLVMSFZBN-UHFFFAOYSA-N
SMILES :CCCCCC(CC(=O)NO)C(=O)NC(C(C)C)C(=O)N1CCCC1CO
CAS DataBase Reference :13434-13-4(CAS DataBase Reference)
Safety Information
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Description
Actinonin is a peptidomimetic antibiotic produced by Actinomyces that inhibits aminopeptidases. It inhibits the following matrix metalloproteinases (MMPs): MMP-1 (Ki = 300 nM), MMP-2 (IC50 = ~90 nM), MMP-3 (Ki = 1,700 nM), MMP-7 (IC50 = ~3,500 nM), MMP-8 (Ki = 130 nM), MMP-9 (Ki = 330 nM), MMP-10 (IC50 = ~500 nM), MMP-12 (IC50 = ~350 nM), and MMP-13 (IC50 = ~100 nM), but not MMP-14 (IC50 > 1 mM). Actinonin acts as an herbicide by targeting plastid peptide deformylase, an enzyme required for N-terminal processing of plastid-encoded proteins. Actinonin has also been identified as an effective inhibitor of human meprin α (Ki = 20 nM), a zinc endopeptidase that cleaves matrix proteins. More recently actinonin has been shown to inhibit tumor cell invasion and matrix degradation and to induce apoptosis in animal models by targeting human mitochondrial peptide deformylase.Related product price
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