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ChemicalBook >> CAS DataBase List >> Baricitinib

Baricitinib

Baricitinib price.
  • $10 - $1872
  • Product name: Baricitinib
  • CAS: 1187594-09-7
  • MF: C16H17N7O2S
  • MW: 371.42
  • EINECS:691-421-4
  • MDL Number:MFCD21608464
  • Synonyms:Baricitinib;INCB 028050;LY 3009104;BARICITINIB;INCB28050;LY3009104;Baricitinib (LY3009104);2-(3-(4-(3H-Pyrrolo[2,3-d]pyriMidin-4-yl)-1H-pyrazol-1-yl)-1-(ethylsulfonyl)azetidin-3-yl)acetonitrile;Baricitinib/INCB 028050/LY3009104;3-Azetidineacetonitrile, 1-(ethylsulfonyl)-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]-
118 prices
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  • aablocks
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  • 10mM(1mLinDMSO)
  • 2mg
  • 10mM(in1mLDMSO)
  • 1mg
  • 10mM(in 1mL DMSO)
  • 50
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  • 10mM*1mLinDMSO
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  • 10 mg
  • Manufactureraablocks
  • Product numberAA003A32
  • Product description1-(Ethylsulfonyl)-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]-3-azetidineacetonitrile ≥99%
  • Packaging5mg
  • Price$10
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA003A32
  • Product description1-(Ethylsulfonyl)-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]-3-azetidineacetonitrile ≥99%
  • Packaging10mg
  • Price$11
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA003A32
  • Product description1-(Ethylsulfonyl)-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]-3-azetidineacetonitrile ≥99%
  • Packaging50mg
  • Price$24
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA003A32
  • Product description1-(Ethylsulfonyl)-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]-3-azetidineacetonitrile 99%
  • Packaging250mg
  • Price$48
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA003A32
  • Product description1-(Ethylsulfonyl)-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]-3-azetidineacetonitrile 98%
  • Packaging1g
  • Price$63
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA003A32
  • Product description1-(Ethylsulfonyl)-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]-3-azetidineacetonitrile 98%
  • Packaging5g
  • Price$146
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA003A32
  • Product description1-(Ethylsulfonyl)-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]-3-azetidineacetonitrile 98%
  • Packaging25g
  • Price$407
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA003A32
  • Product description1-(Ethylsulfonyl)-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]-3-azetidineacetonitrile 98%
  • Packaging100g
  • Price$1342
  • Updated2026-05-28
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  • ManufacturerACHEMBLOCK
  • Product numberG-5743
  • Product descriptionBaricitinib 98%
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  • Updated2026-05-25
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  • Product numberG-5743
  • Product descriptionBaricitinib 98%
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  • Product numberG-5743
  • Product descriptionBaricitinib 98%
  • Packaging500MG
  • Price$70
  • Updated2026-05-27
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Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA003A32 1-(Ethylsulfonyl)-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]-3-azetidineacetonitrile ≥99% 5mg $10 2026-05-28 Buy
aablocks AA003A32 1-(Ethylsulfonyl)-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]-3-azetidineacetonitrile ≥99% 10mg $11 2026-05-28 Buy
aablocks AA003A32 1-(Ethylsulfonyl)-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]-3-azetidineacetonitrile ≥99% 50mg $24 2026-05-28 Buy
aablocks AA003A32 1-(Ethylsulfonyl)-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]-3-azetidineacetonitrile 99% 250mg $48 2026-05-28 Buy
aablocks AA003A32 1-(Ethylsulfonyl)-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]-3-azetidineacetonitrile 98% 1g $63 2026-05-28 Buy
aablocks AA003A32 1-(Ethylsulfonyl)-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]-3-azetidineacetonitrile 98% 5g $146 2026-05-28 Buy
aablocks AA003A32 1-(Ethylsulfonyl)-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]-3-azetidineacetonitrile 98% 25g $407 2026-05-28 Buy
aablocks AA003A32 1-(Ethylsulfonyl)-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]-3-azetidineacetonitrile 98% 100g $1342 2026-05-28 Buy
ACHEMBLOCK G-5743 Baricitinib 98% 5G $390 2026-05-25 Buy
ACHEMBLOCK G-5743 Baricitinib 98% 5G $390 2026-05-27 Buy
ACHEMBLOCK G-5743 Baricitinib 98% 25G $1200 2026-05-25 Buy
ACHEMBLOCK G-5743 Baricitinib 98% 25G $1200 2026-05-27 Buy
ACHEMBLOCK G-5743 Baricitinib 98% 1G $130 2026-05-25 Buy
ACHEMBLOCK G-5743 Baricitinib 98% 1G $130 2026-05-27 Buy
ACHEMBLOCK G-5743 Baricitinib 98% 500MG $70 2026-05-25 Buy
ACHEMBLOCK G-5743 Baricitinib 98% 500MG $70 2026-05-27 Buy

Properties

Melting point :212-215°C
Density :1.56
storage temp. :-20°C
solubility :Soluble in DMSO (up to 30 mg/ml) or in DMF (up to 50 mg/ml).
pka :11.66±0.50(Predicted)
form :solid
color :White or off-white
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or DMF may be stored at -20°C for up to 3 months.
InChI :InChI=1S/C16H17N7O2S/c1-2-26(24,25)22-9-16(10-22,4-5-17)23-8-12(7-21-23)14-13-3-6-18-15(13)20-11-19-14/h3,6-8,11H,2,4,9-10H2,1H3,(H,18,19,20)
InChIKey :XUZMWHLSFXCVMG-UHFFFAOYSA-N
SMILES :N1(S(CC)(=O)=O)CC(N2C=C(C3N=CN=C4NC=CC4=3)C=N2)(CC#N)C1

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Janus kinases (JAKs) are non-receptor kinases that mediate signaling through cytokine receptors, often to members of the signal transducer and activator of transcription (Stat) family. Baricitinib is an orally bioavailable, reversible inhibitor of JAK1 and JAK2 (IC50s = 5.9 and 5.7 nM, respectively) that has been shown to inhibit cytokine-induced phosphorylation of STAT3 in healthy human volunteers. It has potential application in various inflammatory disorders, including rheumatoid arthritis.

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