Dovitinib
|
- $12 - $6121.5
- Product name: Dovitinib
- CAS: 405169-16-6
- MF: C21H21FN6O
- MW: 392.43
- EINECS:1308068-626-2
- MDL Number:MFCD11870802
- Synonyms:4-Amino-5-fluoro-3-[5-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]quinolin-2(1H)-one;dovitinib;Unii-I35H55G906;CHIR258 7.7G;TKI-258;4-amino-5-fluoro-3-[6-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]quinolin-2(1H)-one;CHIR-258(Dovitinib,TKI258);CHIR-258(Dovitinib)
76 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- AvaChem
- Biorbyt Ltd
- Biosynth
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Labseeker
- Matrix Scientific
- Sigma-Aldrich
Package
- 1mg
- 5mg
- 10mg
- 25MG
- 50mg
- 50.00mg
- 100.00mg
- 100MG
- 200mg
- 250.00mg
- 250mg
- 500mg
- 1g
- 5G
- 10 mg
- 50 mg
- 10mM*1mLinDMSO
- Manufactureraablocks
- Product numberAA0076VB
- Product description4-Amino-5-fluoro-3-(6-(4-methylpiperazin-1-yl)-1H-benzo[d]imidazol-2-yl)quinolin-2(1H)-one 99%
- Packaging1mg
- Price$12
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0076VB
- Product description4-Amino-5-fluoro-3-(6-(4-methylpiperazin-1-yl)-1H-benzo[d]imidazol-2-yl)quinolin-2(1H)-one 99%
- Packaging5mg
- Price$22
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0076VB
- Product description4-Amino-5-fluoro-3-(6-(4-methylpiperazin-1-yl)-1H-benzo[d]imidazol-2-yl)quinolin-2(1H)-one 99%
- Packaging10mg
- Price$31
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0076VB
- Product description4-Amino-5-fluoro-3-(6-(4-methylpiperazin-1-yl)-1H-benzo[d]imidazol-2-yl)quinolin-2(1H)-one 99%
- Packaging50mg
- Price$79
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0076VB
- Product description4-Amino-5-fluoro-3-(6-(4-methylpiperazin-1-yl)-1H-benzo[d]imidazol-2-yl)quinolin-2(1H)-one 97%
- Packaging250mg
- Price$280
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0076VB
- Product description4-Amino-5-fluoro-3-(6-(4-methylpiperazin-1-yl)-1H-benzo[d]imidazol-2-yl)quinolin-2(1H)-one 97%
- Packaging1g
- Price$768
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberM15657
- Product descriptionDovitinib 98%
- Packaging1G
- Price$630
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberM15657
- Product descriptionDovitinib 98%
- Packaging25MG
- Price$45
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberM15657
- Product descriptionDovitinib 98%
- Packaging100MG
- Price$140
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product numberJ54360
- Product descriptionDovitinib
- Packaging25mg
- Price$199
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0002571
- Product descriptionDOVITINIB 95.00%
- Packaging1MG
- Price$191.1
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0002571
- Product descriptionDOVITINIB 95.00%
- Packaging5G
- Price$6121.5
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA2168
- Product descriptionDovitinib (TKI-258, CHIR-258)
- Packaging25mg
- Price$176
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA2168
- Product descriptionDovitinib(TKI-258,CHIR-258)
- Packaging25mg
- Price$150
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA2168
- Product descriptionDovitinib (TKI-258, CHIR-258)
- Packaging5mg
- Price$55
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA2168
- Product descriptionDovitinib (TKI-258, CHIR-258)
- Packaging100mg
- Price$440
- Updated2026-05-06
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA0076VB | 4-Amino-5-fluoro-3-(6-(4-methylpiperazin-1-yl)-1H-benzo[d]imidazol-2-yl)quinolin-2(1H)-one 99% | 1mg | $12 | 2026-05-28 | Buy |
| aablocks | AA0076VB | 4-Amino-5-fluoro-3-(6-(4-methylpiperazin-1-yl)-1H-benzo[d]imidazol-2-yl)quinolin-2(1H)-one 99% | 5mg | $22 | 2026-05-28 | Buy |
| aablocks | AA0076VB | 4-Amino-5-fluoro-3-(6-(4-methylpiperazin-1-yl)-1H-benzo[d]imidazol-2-yl)quinolin-2(1H)-one 99% | 10mg | $31 | 2026-05-28 | Buy |
| aablocks | AA0076VB | 4-Amino-5-fluoro-3-(6-(4-methylpiperazin-1-yl)-1H-benzo[d]imidazol-2-yl)quinolin-2(1H)-one 99% | 50mg | $79 | 2026-05-28 | Buy |
| aablocks | AA0076VB | 4-Amino-5-fluoro-3-(6-(4-methylpiperazin-1-yl)-1H-benzo[d]imidazol-2-yl)quinolin-2(1H)-one 97% | 250mg | $280 | 2026-05-28 | Buy |
| aablocks | AA0076VB | 4-Amino-5-fluoro-3-(6-(4-methylpiperazin-1-yl)-1H-benzo[d]imidazol-2-yl)quinolin-2(1H)-one 97% | 1g | $768 | 2026-05-28 | Buy |
| ACHEMBLOCK | M15657 | Dovitinib 98% | 1G | $630 | 2026-05-27 | Buy |
| ACHEMBLOCK | M15657 | Dovitinib 98% | 25MG | $45 | 2026-05-27 | Buy |
| ACHEMBLOCK | M15657 | Dovitinib 98% | 100MG | $140 | 2026-05-27 | Buy |
| AK Scientific | J54360 | Dovitinib | 25mg | $199 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0002571 | DOVITINIB 95.00% | 1MG | $191.1 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0002571 | DOVITINIB 95.00% | 5G | $6121.5 | 2021-12-16 | Buy |
| ApexBio Technology | A2168 | Dovitinib (TKI-258, CHIR-258) | 25mg | $176 | 2026-05-06 | Buy |
| ApexBio Technology | A2168 | Dovitinib(TKI-258,CHIR-258) | 25mg | $150 | 2021-12-16 | Buy |
| ApexBio Technology | A2168 | Dovitinib (TKI-258, CHIR-258) | 5mg | $55 | 2026-05-06 | Buy |
| ApexBio Technology | A2168 | Dovitinib (TKI-258, CHIR-258) | 100mg | $440 | 2026-05-06 | Buy |
Properties
Density :1.386
storage temp. :-20°
solubility :Soluble in DMSO (up to 30 mg/ml).
form :solid
pka :9.44±0.70(Predicted)
color :Yellow-green
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
InChI :InChI=1S/C21H21FN6O/c1-27-7-9-28(10-8-27)12-5-6-14-16(11-12)25-20(24-14)18-19(23)17-13(22)3-2-4-15(17)26-21(18)29/h2-6,11H,7-10H2,1H3,(H,24,25)(H3,23,26,29)
InChIKey :PIQCTGMSNWUMAF-UHFFFAOYSA-N
SMILES :N1C2=C(C(F)=CC=C2)C(N)=C(C2NC3=CC(N4CCN(C)CC4)=CC=C3N=2)C1=O
CAS DataBase Reference :405169-16-6
storage temp. :-20°
solubility :Soluble in DMSO (up to 30 mg/ml).
form :solid
pka :9.44±0.70(Predicted)
color :Yellow-green
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
InChI :InChI=1S/C21H21FN6O/c1-27-7-9-28(10-8-27)12-5-6-14-16(11-12)25-20(24-14)18-19(23)17-13(22)3-2-4-15(17)26-21(18)29/h2-6,11H,7-10H2,1H3,(H,24,25)(H3,23,26,29)
InChIKey :PIQCTGMSNWUMAF-UHFFFAOYSA-N
SMILES :N1C2=C(C(F)=CC=C2)C(N)=C(C2NC3=CC(N4CCN(C)CC4)=CC=C3N=2)C1=O
CAS DataBase Reference :405169-16-6
Safety Information
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Description
Dovitinib is a receptor tyrosine kinase inhibitor that targets vascular endothelial growth factor-2, basic fibroblast growth factor-1, and platelet-derived growth factor β receptors (IC50s = 65, 11, and 5 nM, respectively). By impairing these kinase signals, 1 μM dovitinib has been shown to prevent the growth and motility of pancreatic cancer cell lines (HPAF-II, BxPC-3, MiaPaCa2, and L3.6pl). At 0.04 μM, dovitinib can inhibit endothelial cell proliferation and motility. These antiangiogenic effects have been proposed to be the mechanism by which dovitinib inhibits hepatocellular carcinoma growth and metastasis. Dovitinib has been evaluated in clinical trials for the treatment of advanced solid tumors.More related product prices
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career henan chemical co
![4-Amino-5-fluoro-3-[5-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]quinolin-2(1H)-one](https://img.chemicalbook.com/ProductImageEN/2018-12/small/fe498182-1055-4d7c-bbd5-8bbb37f80631.png)
$2.00
4-Amino-5-fluoro-3-[5-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]quinolin-2(1H)-one CAS:405169-16-6
4-Amino-5-fluoro-3-[5-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]quinolin-2(1H)-one CAS:405169-16-6
Wuhan Nutra Biotechnology Co.,Ltd
Shanghai Yingrui Biopharma Co., Ltd.
ATK CHEMICAL COMPANY LIMITED
CONIER CHEM AND PHARMA LIMITED
SHANGHAI T&W PHARMACEUTICAL CO., LTD.
Tianjin Xinshengjiahe Science & Technology Development Co,.Ltd
Dideu Industries Group Limited
BOC Sciences
CHIR-258(Dovitinib,TKI258)
CAS:405169-16-6