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ChemicalBook >> CAS DataBase List >> PD168393

PD168393

PD168393 price.
  • $13 - $1500
  • Product name: PD168393
  • CAS: 194423-15-9
  • MF: C17H13BrN4O
  • MW: 369.22
  • EINECS:
  • MDL Number:MFCD02179207
  • Synonyms:4-[(3-BROMOPHENYL)AMINO]-6-ACRYLAMIDOQUINAZOLINE;PD 168393;N-[4-[(3-Bromophenyl)amino]-6-quinazolinyl]-2-propenamide;2-Propenamide, N-[4-[(3-bromophenyl)amino]-6-quinazolinyl]-;N-(4-((3-Bromophenyl)amino)quinazolin-6-yl)acrylamide;PD168393;PD-168393;PD 168393;CS-2316;N-[4-(3-Bromoanilino)quinazolin-6-yl]prop-2-enamide
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  • 10mM*1mLinDMSO
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  • 10mM(in 1mL DMSO)
  • 10mg
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  • 1G
  • 10mM(in1mLDMSO)
  • 250mg
  • ManufacturerA2B
  • Product numberAE98516
  • Product descriptionN-(4-((3-Bromophenyl)amino)quinazolin-6-yl)acrylamide 99%
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  • Product descriptionN-(4-((3-Bromophenyl)amino)quinazolin-6-yl)acrylamide 99%
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  • Product descriptionN-(4-((3-Bromophenyl)amino)quinazolin-6-yl)acrylamide 99%
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  • Product descriptionN-(4-((3-Bromophenyl)amino)quinazolin-6-yl)acrylamide 99%
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  • Product descriptionN-(4-((3-Bromophenyl)amino)quinazolin-6-yl)acrylamide 99+%
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  • Product descriptionN-(4-((3-Bromophenyl)amino)quinazolin-6-yl)acrylamide 99+%
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  • Product descriptionN-(4-((3-Bromophenyl)amino)quinazolin-6-yl)acrylamide 99+%
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  • Product numberAA00AOQG
  • Product descriptionN-(4-((3-Bromophenyl)amino)quinazolin-6-yl)acrylamide 99+%
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Manufacturer Product number Product description Packaging Price Updated Buy
A2B AE98516 N-(4-((3-Bromophenyl)amino)quinazolin-6-yl)acrylamide 99% 1mg $13 2026-05-25 Buy
A2B AE98516 N-(4-((3-Bromophenyl)amino)quinazolin-6-yl)acrylamide 99% 2mg $16 2026-05-25 Buy
A2B AE98516 N-(4-((3-Bromophenyl)amino)quinazolin-6-yl)acrylamide 99% 5mg $20 2026-05-25 Buy
A2B AE98516 N-(4-((3-Bromophenyl)amino)quinazolin-6-yl)acrylamide 99% 10mg $29 2026-05-25 Buy
A2B AE98516 N-(4-((3-Bromophenyl)amino)quinazolin-6-yl)acrylamide 99% 25mg $41 2026-05-25 Buy
A2B AE98516 N-(4-((3-Bromophenyl)amino)quinazolin-6-yl)acrylamide 99% 50mg $62 2026-05-25 Buy
A2B AE98516 N-(4-((3-Bromophenyl)amino)quinazolin-6-yl)acrylamide 99% 100mg $84 2026-05-25 Buy
A2B AE98516 N-(4-((3-Bromophenyl)amino)quinazolin-6-yl)acrylamide 99% 250mg $133 2026-05-25 Buy
aablocks AA00AOQG N-(4-((3-Bromophenyl)amino)quinazolin-6-yl)acrylamide 99+% 100mg $93 2026-05-28 Buy
aablocks AA00AOQG N-(4-((3-Bromophenyl)amino)quinazolin-6-yl)acrylamide 99+% 50mg $68 2026-05-28 Buy
aablocks AA00AOQG N-(4-((3-Bromophenyl)amino)quinazolin-6-yl)acrylamide 99+% 25mg $46 2026-05-28 Buy
aablocks AA00AOQG N-(4-((3-Bromophenyl)amino)quinazolin-6-yl)acrylamide 99+% 10mg $32 2026-05-28 Buy
aablocks AA00AOQG N-(4-((3-Bromophenyl)amino)quinazolin-6-yl)acrylamide 99+% 2mg $18 2026-05-28 Buy
aablocks AA00AOQG N-(4-((3-Bromophenyl)amino)quinazolin-6-yl)acrylamide 99+% 5mg $23 2026-05-28 Buy
aablocks AA00AOQG N-(4-((3-Bromophenyl)amino)quinazolin-6-yl)acrylamide 99+% 1mg $15 2026-05-28 Buy
aablocks AA00AOQG N-(4-((3-Bromophenyl)amino)quinazolin-6-yl)acrylamide 99+% 250mg $148 2026-05-28 Buy

Properties

Melting point :279℃
Boiling point :571.1±50.0 °C(Predicted)
Density :1.558±0.06 g/cm3(Predicted)
storage temp. :room temp
solubility :insoluble in H2O; ≥1 mg/mL in EtOH with gentle warming and ultrasonic; ≥18.45 mg/mL in DMSO
form :powder
pka :12.19±0.43(Predicted)
color :white to beige
InChI :InChI=1S/C17H13BrN4O/c1-2-16(23)21-13-6-7-15-14(9-13)17(20-10-19-15)22-12-5-3-4-11(18)8-12/h2-10H,1H2,(H,21,23)(H,19,20,22)
InChIKey :HTUBKQUPEREOGA-UHFFFAOYSA-N
SMILES :C(NC1C=CC2C(C=1)=C(NC1=CC=CC(Br)=C1)N=CN=2)(=O)C=C

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312 Call a POISON CENTER or doctor/physician if you feel unwell.
P321 Specific treatment (see … on this label).
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P362 Take off contaminated clothing and wash before reuse.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

PD 168393 is a potent, irreversible, cell-permeable and selective inhibitor of EGFR (epidermal growth factor receptor). Does not inhibit any other protein kinases. PD 168393 binds to the catalytic domain of the EGFR (EGF receptor tyrosine kinase) with a 1:1 stoichiometry and alkylating Cys773.

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