TAK-632
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- $28 - $2691.1
- Product name: TAK-632
- CAS: 1228591-30-7
- MF: C27H18F4N4O3S
- MW: 554.52
- EINECS:200-256-5
- MDL Number:MFCD26960965
- Synonyms:TAK-632;N-(7-CYANO-6-(4-FLUORO-3-(2-(3-(TRIFLUOROMETHYL)PHENYL)ACETAMIDO)PHENOXY)BENZO[D]THIAZOL-2-YL)CYCLOPROPANECARBOXAMIDE;N-[7-Cyano-6-[4-fluoro-3-[[[3-(trifluoromethyl)phenyl]acetyl]amino]phenoxy]-1,3-benzothiazol-2-yl]cyclopropanecarboxamide;TAK-0632;N-[7-Cyano-6-[4-fluoro-3-[[[3-(trifluoromethyl)phenyl]acetyl]amino]phenoxy]-1,3-benzothiazol-2-yl]cyclopropanecarboxamide TAK632;TAK 632 N-[7-Cyano-6-[4-fluoro-3-[[[3-(trifluoromethyl)phenyl]acetyl]amino]phenoxy]-1,3-benzothiazol-2-yl]cyclopropanecarboxamide;TAK-632, >=98%;TAK2 63 (Free base)
83 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- Adipogen Life Sciences
- AK Scientific
- ApexBio Technology
- Arctom
- Biorbyt Ltd
- Biosynth
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Medical Isotopes, Inc.
- TRC
Package
- EvaluationSample
- 1unit
- 20mg
- 10mM(in1mLDMSO)
- 10mM*1mLinDMSO(Solid+Solvent)
- 10mM*1mLinDMSO
- 250mg
- 10mM*1mLinDMSO(Solution)
- 1000mg
- 1mg
- 5mg
- 25mg
- 10mM(in 1mL DMSO)
- 10mg
- 50mg
- 100mg
- 200mg
- 1G
- Manufactureraablocks
- Product numberAA000JJ9
- Product descriptionN-[7-Cyano-6-[4-fluoro-3-[[[3-(trifluoromethyl)phenyl]acetyl]amino]phenoxy]-1,3-benzothiazol-2-yl]cyclopropanecarboxamide
- Packaging5mg
- Price$48
- Updated2026-05-25
- Buy
- Manufactureraablocks
- Product numberAA000JJ9
- Product descriptionN-[7-Cyano-6-[4-fluoro-3-[[[3-(trifluoromethyl)phenyl]acetyl]amino]phenoxy]-1,3-benzothiazol-2-yl]cyclopropanecarboxamide ≥98%
- Packaging1mg
- Price$36
- Updated2026-05-25
- Buy
- Manufactureraablocks
- Product numberAA000JJ9
- Product descriptionN-[7-Cyano-6-[4-fluoro-3-[[[3-(trifluoromethyl)phenyl]acetyl]amino]phenoxy]-1,3-benzothiazol-2-yl]cyclopropanecarboxamide 98%
- Packaging10mg
- Price$51
- Updated2026-05-25
- Buy
- Manufactureraablocks
- Product numberAA000JJ9
- Product descriptionN-[7-Cyano-6-[4-fluoro-3-[[[3-(trifluoromethyl)phenyl]acetyl]amino]phenoxy]-1,3-benzothiazol-2-yl]cyclopropanecarboxamide
- Packaging25mg
- Price$83
- Updated2026-05-25
- Buy
- Manufactureraablocks
- Product numberAA000JJ9
- Product descriptionN-[7-Cyano-6-[4-fluoro-3-[[[3-(trifluoromethyl)phenyl]acetyl]amino]phenoxy]-1,3-benzothiazol-2-yl]cyclopropanecarboxamide
- Packaging50mg
- Price$121
- Updated2026-05-25
- Buy
- Manufactureraablocks
- Product numberAA000JJ9
- Product descriptionN-[7-Cyano-6-[4-fluoro-3-[[[3-(trifluoromethyl)phenyl]acetyl]amino]phenoxy]-1,3-benzothiazol-2-yl]cyclopropanecarboxamide
- Packaging100mg
- Price$199
- Updated2026-05-25
- Buy
- Manufactureraablocks
- Product numberAA000JJ9
- Product descriptionN-[7-Cyano-6-[4-fluoro-3-[[[3-(trifluoromethyl)phenyl]acetyl]amino]phenoxy]-1,3-benzothiazol-2-yl]cyclopropanecarboxamide
- Packaging200mg
- Price$252
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product numberO33834
- Product descriptionTAK-632 98%
- Packaging100MG
- Price$295
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product numberO33834
- Product descriptionTAK-632 98%
- Packaging100MG
- Price$295
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberO33834
- Product descriptionTAK-632 98%
- Packaging25MG
- Price$120
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product numberO33834
- Product descriptionTAK-632 98%
- Packaging25MG
- Price$120
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberO33834
- Product descriptionTAK-632 98%
- Packaging5MG
- Price$45
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product numberO33834
- Product descriptionTAK-632 98%
- Packaging5MG
- Price$45
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberO33834
- Product descriptionTAK-632 98%
- Packaging1G
- Price$1250
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product numberO33834
- Product descriptionTAK-632 98%
- Packaging1G
- Price$1250
- Updated2026-05-27
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1203-M100
- Product descriptionTAK-632 ≥95%
- Packaging100mg
- Price$1069
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA000JJ9 | N-[7-Cyano-6-[4-fluoro-3-[[[3-(trifluoromethyl)phenyl]acetyl]amino]phenoxy]-1,3-benzothiazol-2-yl]cyclopropanecarboxamide | 5mg | $48 | 2026-05-25 | Buy |
| aablocks | AA000JJ9 | N-[7-Cyano-6-[4-fluoro-3-[[[3-(trifluoromethyl)phenyl]acetyl]amino]phenoxy]-1,3-benzothiazol-2-yl]cyclopropanecarboxamide ≥98% | 1mg | $36 | 2026-05-25 | Buy |
| aablocks | AA000JJ9 | N-[7-Cyano-6-[4-fluoro-3-[[[3-(trifluoromethyl)phenyl]acetyl]amino]phenoxy]-1,3-benzothiazol-2-yl]cyclopropanecarboxamide 98% | 10mg | $51 | 2026-05-25 | Buy |
| aablocks | AA000JJ9 | N-[7-Cyano-6-[4-fluoro-3-[[[3-(trifluoromethyl)phenyl]acetyl]amino]phenoxy]-1,3-benzothiazol-2-yl]cyclopropanecarboxamide | 25mg | $83 | 2026-05-25 | Buy |
| aablocks | AA000JJ9 | N-[7-Cyano-6-[4-fluoro-3-[[[3-(trifluoromethyl)phenyl]acetyl]amino]phenoxy]-1,3-benzothiazol-2-yl]cyclopropanecarboxamide | 50mg | $121 | 2026-05-25 | Buy |
| aablocks | AA000JJ9 | N-[7-Cyano-6-[4-fluoro-3-[[[3-(trifluoromethyl)phenyl]acetyl]amino]phenoxy]-1,3-benzothiazol-2-yl]cyclopropanecarboxamide | 100mg | $199 | 2026-05-25 | Buy |
| aablocks | AA000JJ9 | N-[7-Cyano-6-[4-fluoro-3-[[[3-(trifluoromethyl)phenyl]acetyl]amino]phenoxy]-1,3-benzothiazol-2-yl]cyclopropanecarboxamide | 200mg | $252 | 2026-05-25 | Buy |
| ACHEMBLOCK | O33834 | TAK-632 98% | 100MG | $295 | 2026-05-25 | Buy |
| ACHEMBLOCK | O33834 | TAK-632 98% | 100MG | $295 | 2026-05-27 | Buy |
| ACHEMBLOCK | O33834 | TAK-632 98% | 25MG | $120 | 2026-05-25 | Buy |
| ACHEMBLOCK | O33834 | TAK-632 98% | 25MG | $120 | 2026-05-27 | Buy |
| ACHEMBLOCK | O33834 | TAK-632 98% | 5MG | $45 | 2026-05-25 | Buy |
| ACHEMBLOCK | O33834 | TAK-632 98% | 5MG | $45 | 2026-05-27 | Buy |
| ACHEMBLOCK | O33834 | TAK-632 98% | 1G | $1250 | 2026-05-25 | Buy |
| ACHEMBLOCK | O33834 | TAK-632 98% | 1G | $1250 | 2026-05-27 | Buy |
| Adipogen Life Sciences | SYN-1203-M100 | TAK-632 ≥95% | 100mg | $1069 | 2021-12-16 | Buy |
Properties
Density :1.52±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :≥27.75 mg/mL in DMSO; insoluble in H2O; ≥2.23 mg/mL in EtOH with gentle warming and ultrasonic
form :solid
pka :9.59±0.70(Predicted)
color :White to off-white
storage temp. :Store at -20°C
solubility :≥27.75 mg/mL in DMSO; insoluble in H2O; ≥2.23 mg/mL in EtOH with gentle warming and ultrasonic
form :solid
pka :9.59±0.70(Predicted)
color :White to off-white
Safety Information
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| Signal word: | Warning | ||||||||||||||
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Description
TAK-632 is a slow off-rate inhibitor of Raf kinases (IC50s = 8.3, 2.4, and 1.4 nM for wild type B-Raf, mutant B-RafV600E, and c-Raf, respectively). It demonstrates 14-1,200-fold selectivity for Raf over a panel of 26 different kinases. TAK-632 shows significant antiproliferative activity against mutated B-Raf or mutated N-Ras cancer cell lines and xenograft models, inhibiting MEK phosphorylation with an IC50 value of 12 nM and downstream ERK phosphorylation with an IC50 value of 16 nM.Related product price
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Suppliers and manufacturers
ATK CHEMICAL COMPANY LIMITED
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Zhejiang J&C Biological Technology Co.,Limited
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ShenZhen Trendseen Biological Technology Co.,Ltd.
Zibo Hangyu Biotechnology Development Co., Ltd
Aladdin Scientific
