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ChemicalBook >> CAS DataBase List >> Trifluoroacetic anhydride

Trifluoroacetic anhydride

Trifluoroacetic anhydride price.
  • $9 - $14750
  • Product name: Trifluoroacetic anhydride
  • CAS: 407-25-0
  • MF: C4F6O3
  • MW: 210.03
  • EINECS:206-982-9
  • MDL Number:MFCD00000416
  • Synonyms:TRIFLUOROACETO ANHYDRIDE;Trifluoroacetic acid anhydride (TFAH);RIFLUOROACETIC ANHYDRIDE;Trifluoroacetic anhydride, min. 98%;trifluoroacetyl 2,2,2-trifluoroacetate;Trifluoroacetic anhydride, 99+% 100GR;Trifluoroacetic anhydride, 99+% 25GR;Trifluoracetic anhydride, min. 98%
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  • ManufacturerAHH
  • Product numberMT-59874
  • Product descriptionTrifluoroaceticacidanhydride 98%
  • Packaging1000g
  • Price$130
  • Updated2021-12-16
  • Buy
  • ManufacturerAHH
  • Product numberMT-59874
  • Product descriptionTrifluoroacetic acid anhydride 97%
  • Packaging1000g
  • Price$130
  • Updated2026-05-25
  • Buy
  • ManufacturerAHH
  • Product numberMT-59874
  • Product descriptionTrifluoroacetic acid anhydride 97%
  • Packaging1000g
  • Price$130
  • Updated2026-05-26
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPN0000442
  • Product descriptionTRIFLUOROACETIC ANHYDRIDE 95.00%
  • Packaging25ML
  • Price$129
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPN0000442
  • Product descriptionTRIFLUOROACETIC ANHYDRIDE 95.00%
  • Packaging1KG
  • Price$6448.55
  • Updated2021-12-16
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  • ManufacturerApolloscientific
  • Product numberPC7170
  • Product descriptionTrifluoroacetic anhydride 99%
  • Packaging5Kg
  • Price$265
  • Updated2021-12-16
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  • ManufacturerApolloscientific
  • Product numberPC7170
  • Product descriptionTrifluoroacetic anhydride 99%
  • Packaging500g
  • Price$34
  • Updated2021-12-16
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  • ManufacturerApolloscientific
  • Product numberPC7170
  • Product descriptionTrifluoroacetic anhydride 99%
  • Packaging100g
  • Price$36
  • Updated2026-06-04
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  • ManufacturerApolloscientific
  • Product numberPC7170
  • Product descriptionTrifluoroacetic anhydride 99%
  • Packaging500g
  • Price$55
  • Updated2026-06-04
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  • ManufacturerApolloscientific
  • Product numberPC7170
  • Product descriptionTrifluoroacetic anhydride 99%
  • Packaging1Kg
  • Price$58
  • Updated2021-12-16
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  • ManufacturerApolloscientific
  • Product numberPC7170
  • Product descriptionTrifluoroacetic anhydride 99%
  • Packaging1kg
  • Price$96
  • Updated2026-06-04
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  • ManufacturerChem-Impex
  • Product number00291
  • Product descriptionTrifluoroacetic anhydride ≥99%(Assay)
  • Packaging250G
  • Price$65
  • Updated2026-05-19
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  • ManufacturerChem-Impex
  • Product number00291
  • Product descriptionTrifluoroaceticanhydride,99.5%(Titration) 99.5%(Titration)
  • Packaging100G
  • Price$21.28
  • Updated2021-12-16
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  • ManufacturerChem-Impex
  • Product number00291
  • Product descriptionTrifluoroacetic anhydride ≥99%(Assay)
  • Packaging100G
  • Price$30
  • Updated2026-05-19
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  • ManufacturerChem-Impex
  • Product number00291
  • Product descriptionTrifluoroaceticanhydride,99.5%(Titration) 99.5%(Titration)
  • Packaging250G
  • Price$42.56
  • Updated2021-12-16
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  • ManufacturerChem-Impex
  • Product number00291
  • Product descriptionTrifluoroaceticanhydride,99.5%(Titration) 99.5%(Titration)
  • Packaging25G
  • Price$13.31
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AHH MT-59874 Trifluoroaceticacidanhydride 98% 1000g $130 2021-12-16 Buy
AHH MT-59874 Trifluoroacetic acid anhydride 97% 1000g $130 2026-05-25 Buy
AHH MT-59874 Trifluoroacetic acid anhydride 97% 1000g $130 2026-05-26 Buy
American Custom Chemicals Corporation APN0000442 TRIFLUOROACETIC ANHYDRIDE 95.00% 25ML $129 2021-12-16 Buy
American Custom Chemicals Corporation APN0000442 TRIFLUOROACETIC ANHYDRIDE 95.00% 1KG $6448.55 2021-12-16 Buy
Apolloscientific PC7170 Trifluoroacetic anhydride 99% 5Kg $265 2021-12-16 Buy
Apolloscientific PC7170 Trifluoroacetic anhydride 99% 500g $34 2021-12-16 Buy
Apolloscientific PC7170 Trifluoroacetic anhydride 99% 100g $36 2026-06-04 Buy
Apolloscientific PC7170 Trifluoroacetic anhydride 99% 500g $55 2026-06-04 Buy
Apolloscientific PC7170 Trifluoroacetic anhydride 99% 1Kg $58 2021-12-16 Buy
Apolloscientific PC7170 Trifluoroacetic anhydride 99% 1kg $96 2026-06-04 Buy
Chem-Impex 00291 Trifluoroacetic anhydride ≥99%(Assay) 250G $65 2026-05-19 Buy
Chem-Impex 00291 Trifluoroaceticanhydride,99.5%(Titration) 99.5%(Titration) 100G $21.28 2021-12-16 Buy
Chem-Impex 00291 Trifluoroacetic anhydride ≥99%(Assay) 100G $30 2026-05-19 Buy
Chem-Impex 00291 Trifluoroaceticanhydride,99.5%(Titration) 99.5%(Titration) 250G $42.56 2021-12-16 Buy
Chem-Impex 00291 Trifluoroaceticanhydride,99.5%(Titration) 99.5%(Titration) 25G $13.31 2021-12-16 Buy

Properties

Melting point :-65 °C (lit.)
Boiling point :39.5-40 °C (lit.)
Density :1.511 g/mL at 20 °C (lit.)
vapor pressure :6.28 psi ( 20 °C)
refractive index :n20/D 1.3(lit.)
Flash point :-26 °C
storage temp. :2-8°C
solubility :Miscible with benzene, dichloromethane, diethyl ether, dimethylformamide, terahydrofuran and acetonitrile.
form :Liquid
pka :0.43[at 20 ℃]
Specific Gravity :1.487
color :Clear
Water Solubility :Hydrolysis
Sensitive :Moisture Sensitive
BRN :746197
Stability :Stable, but moisture sensitive. Reacts with water to liberate hydrogen (flammable!). Incompatible with water, strong oxidizing agents.
InChI :1S/C4F6O3/c5-3(6,7)1(11)13-2(12)4(8,9)10
InChIKey :QAEDZJGFFMLHHQ-UHFFFAOYSA-N
SMILES :FC(F)(F)C(=O)OC(=O)C(F)(F)F
LogP :0.79 at 25℃
CAS DataBase Reference :407-25-0(CAS DataBase Reference)
NIST Chemistry Reference :Acetic acid, trifluoro-, anhydride(407-25-0)
EPA Substance Registry System :Acetic acid, trifluoro-, anhydride (407-25-0)

Safety Information

Symbol(GHS): Corrosion (GHS05)Exclamation Mark (GHS07)
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H290 May be corrosive to metals Corrosive to Metals Category 1 Warning P234, P390, P404
H314 Causes severe skin burns and eye damage Skin corrosion/irritation Category 1A, B, C Danger P260,P264, P280, P301+P330+ P331,P303+P361+P353, P363, P304+P340,P310, P321, P305+ P351+P338, P405,P501
H412 Harmful to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 3 P273, P501
Precautionary statements:
P234 Keep only in original container.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P330+P331 IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P390 Absorb spillage to prevent material damage.
P405 Store locked up.
P406 Store in corrosive resistant/… container with a resistant inner liner.
P501 Dispose of contents/container to..…

Description

Trifluoroacetic anhydride is used for the introduction of trifluoroacetyl group in organic synthesis. It is involved in the preparation of N- and O-trifluoroacetyl derivatives of a wide range of biologically active compounds for gas chromatography analysis. It plays an important role as desiccant for trifluoroacetic acid. It is also used in the oxidation of aldehydes to acids, esters, amides as well as in the protection of alcohols and amines. In addition, it is used as analytical reagents, solvents and dehydration condensing agent. It serves as an intermediate of fluorine fine chemicals, pharmaceuticals and agrochemicals.

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