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ChemicalBook >> CAS DataBase List >> WYE-687

WYE-687

$48 - $4462.92
Product name: WYE-687
CAS: 1062161-90-3
MF: C28H32N8O3
MW: 528.61
EINECS:
MDL Number:MFCD22417086
Synonyms:methyl 4-(4-morpholino-1-(1-(pyridin-3-ylmethyl)piperidin-4-yl)-1H-pyrazolo[3,4-d]pyrimidin-6-yl)phenylcarbamate;methyl N-[4-[4-morpholin-4-yl-1-[1-(pyridin-3-ylmethyl)piperidin-4-yl]pyrazolo[3,4-d]pyrimidin-6-yl]phenyl]carbamate;WYE-687;WYE 687;WYE687;WYE-687;N-[4-[4-(4-Morpholinyl)-1-[1-(3-pyridinylmethyl)-4-piperidinyl]-1H-pyrazolo[3,4-d]pyrimidin-6-yl]phenyl]carbamic acid methyl ester;N-[4-[4-(4-Morpholinyl)-1-[1-(3-pyridinylmethyl)-4-piperidinyl]-1H-pyrazolo[3,4-d]pyrimidin-6-yl]phenyl]-carbamic acid methyl ester hydrochloride;CS-540;Carbamic acid, N-[4-[4-(4-morpholinyl)-1-[1-(3-pyridinylmethyl)-4-piperidinyl]-1H-pyrazolo[3,4-d]pyrimidin-6-yl]phenyl]-, methyl ester

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aablocks
ACHEMBLOCK
AK Scientific
American Custom Chemicals Corporation
ApexBio Technology
Biosynth
Cayman Chemical
Chemenu
ChemScene
Crysdot
Medical Isotopes, Inc.
Sigma-Aldrich
TRC
Usbiological

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Manufactureraablocks
Product numberAA008THV
Product descriptionMethyl (4-(4-morpholino-1-(1-(pyridin-3-ylmethyl)piperidin-4-yl)-1H-pyrazolo[3,4-d]pyrimidin-6-yl)phenyl)carbamate 98%
Packaging10mg
Price$179
Updated2026-05-28
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Manufactureraablocks
Product numberAA008THV
Product descriptionMethyl (4-(4-morpholino-1-(1-(pyridin-3-ylmethyl)piperidin-4-yl)-1H-pyrazolo[3,4-d]pyrimidin-6-yl)phenyl)carbamate ≥98%
Packaging5mg
Price$156
Updated2026-05-28
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Manufactureraablocks
Product numberAA008THV
Product descriptionMethyl (4-(4-morpholino-1-(1-(pyridin-3-ylmethyl)piperidin-4-yl)-1H-pyrazolo[3,4-d]pyrimidin-6-yl)phenyl)carbamate 98%
Packaging20mg
Price$274
Updated2026-05-28
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Manufactureraablocks
Product numberAA008THV
Product descriptionMethyl (4-(4-morpholino-1-(1-(pyridin-3-ylmethyl)piperidin-4-yl)-1H-pyrazolo[3,4-d]pyrimidin-6-yl)phenyl)carbamate 98%
Packaging50mg
Price$505
Updated2026-05-28
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Manufactureraablocks
Product numberAA008THV
Product descriptionMethyl (4-(4-morpholino-1-(1-(pyridin-3-ylmethyl)piperidin-4-yl)-1H-pyrazolo[3,4-d]pyrimidin-6-yl)phenyl)carbamate 98%
Packaging100mg
Price$785
Updated2026-05-28
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ManufacturerACHEMBLOCK
Product numberV143164
Product descriptionmethyl (4-(4-morpholino-1-(1-(pyridin-3-ylmethyl)piperidin-4-yl)-1H-pyrazolo[3,4-d]pyrimidin-6-yl)phenyl)carbamate 98%
Packaging1G
Price$2640
Updated2026-05-27
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ManufacturerACHEMBLOCK
Product numberV143164
Product descriptionmethyl (4-(4-morpholino-1-(1-(pyridin-3-ylmethyl)piperidin-4-yl)-1H-pyrazolo[3,4-d]pyrimidin-6-yl)phenyl)carbamate 98%
Packaging100MG
Price$530
Updated2026-05-27
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ManufacturerAK Scientific
Product numberX7451
Product descriptionMethyl(4-{4-morpholin-4-yl-1-[1-(pyridin-3-ylmethyl)piperidin-4-yl]-1Hpyrazolo[3,4-d]pyrimidin-6-yl}phenyl)carbamate
Packaging10mg
Price$407
Updated2021-12-16
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ManufacturerAK Scientific
Product numberX7451
Product descriptionMethyl(4-{4-morpholin-4-yl-1-[1-(pyridin-3-ylmethyl)piperidin-4-yl]-1Hpyrazolo[3,4-d]pyrimidin-6-yl}phenyl)carbamate
Packaging1mg
Price$151
Updated2021-12-16
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ManufacturerAmerican Custom Chemicals Corporation
Product numberKIN0001355
Product descriptionWYE-687 95.00%
Packaging5MG
Price$459.8
Updated2021-12-16
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ManufacturerAmerican Custom Chemicals Corporation
Product numberKIN0001355
Product descriptionWYE-687 95.00%
Packaging200MG
Price$4462.92
Updated2021-12-16
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ManufacturerAmerican Custom Chemicals Corporation
Product numberKIN0001355
Product descriptionWYE-687 95.00%
Packaging50MG
Price$2088.36
Updated2021-12-16
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ManufacturerApexBio Technology
Product numberB1638
Product descriptionWYE-687
Packaging50mg
Price$372
Updated2026-05-06
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ManufacturerApexBio Technology
Product numberB1638
Product descriptionWYE-687
Packaging100mg
Price$596
Updated2026-05-06
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ManufacturerApexBio Technology
Product numberB1638
Product descriptionWYE-687
Packaging10mg
Price$111
Updated2026-05-06
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ManufacturerApexBio Technology
Product numberB1638
Product descriptionWYE-687
Packaging10mg
Price$178
Updated2021-12-16
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
aablocks	AA008THV	Methyl (4-(4-morpholino-1-(1-(pyridin-3-ylmethyl)piperidin-4-yl)-1H-pyrazolo[3,4-d]pyrimidin-6-yl)phenyl)carbamate 98%	10mg	$179	2026-05-28	Buy
aablocks	AA008THV	Methyl (4-(4-morpholino-1-(1-(pyridin-3-ylmethyl)piperidin-4-yl)-1H-pyrazolo[3,4-d]pyrimidin-6-yl)phenyl)carbamate ≥98%	5mg	$156	2026-05-28	Buy
aablocks	AA008THV	Methyl (4-(4-morpholino-1-(1-(pyridin-3-ylmethyl)piperidin-4-yl)-1H-pyrazolo[3,4-d]pyrimidin-6-yl)phenyl)carbamate 98%	20mg	$274	2026-05-28	Buy
aablocks	AA008THV	Methyl (4-(4-morpholino-1-(1-(pyridin-3-ylmethyl)piperidin-4-yl)-1H-pyrazolo[3,4-d]pyrimidin-6-yl)phenyl)carbamate 98%	50mg	$505	2026-05-28	Buy
aablocks	AA008THV	Methyl (4-(4-morpholino-1-(1-(pyridin-3-ylmethyl)piperidin-4-yl)-1H-pyrazolo[3,4-d]pyrimidin-6-yl)phenyl)carbamate 98%	100mg	$785	2026-05-28	Buy
ACHEMBLOCK	V143164	methyl (4-(4-morpholino-1-(1-(pyridin-3-ylmethyl)piperidin-4-yl)-1H-pyrazolo[3,4-d]pyrimidin-6-yl)phenyl)carbamate 98%	1G	$2640	2026-05-27	Buy
ACHEMBLOCK	V143164	methyl (4-(4-morpholino-1-(1-(pyridin-3-ylmethyl)piperidin-4-yl)-1H-pyrazolo[3,4-d]pyrimidin-6-yl)phenyl)carbamate 98%	100MG	$530	2026-05-27	Buy
AK Scientific	X7451	Methyl(4-{4-morpholin-4-yl-1-[1-(pyridin-3-ylmethyl)piperidin-4-yl]-1Hpyrazolo[3,4-d]pyrimidin-6-yl}phenyl)carbamate	10mg	$407	2021-12-16	Buy
AK Scientific	X7451	Methyl(4-{4-morpholin-4-yl-1-[1-(pyridin-3-ylmethyl)piperidin-4-yl]-1Hpyrazolo[3,4-d]pyrimidin-6-yl}phenyl)carbamate	1mg	$151	2021-12-16	Buy
American Custom Chemicals Corporation	KIN0001355	WYE-687 95.00%	5MG	$459.8	2021-12-16	Buy
American Custom Chemicals Corporation	KIN0001355	WYE-687 95.00%	200MG	$4462.92	2021-12-16	Buy
American Custom Chemicals Corporation	KIN0001355	WYE-687 95.00%	50MG	$2088.36	2021-12-16	Buy
ApexBio Technology	B1638	WYE-687	50mg	$372	2026-05-06	Buy
ApexBio Technology	B1638	WYE-687	100mg	$596	2026-05-06	Buy
ApexBio Technology	B1638	WYE-687	10mg	$111	2026-05-06	Buy
ApexBio Technology	B1638	WYE-687	10mg	$178	2021-12-16	Buy

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Properties

Density :1.40
storage temp. :Store at -20°C
solubility :insoluble in H2O; insoluble in EtOH; insoluble in DMSO
form :Powder
pka :13.42±0.70(Predicted)
color :Off-white to yellow
InChIKey :VDOCQQKGPJENHJ-UHFFFAOYSA-N
SMILES :N2(CCC(CC2)[n]3ncc4c3nc(nc4N6CCOCC6)c5ccc(cc5)NC(=O)OC)Cc1cnccc1

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Symbol(GHS):

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Code	Hazard statements	Hazard class	Category	Signal word	Pictogram	P-Codes

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Description

WYE-687 is an ATP-competitive and selective inhibitor of mammalian target of rapamycin (mTOR). Studies have shown the combination of Ras-Raf-MEK1/2 inhibitors with WYE-687 may overcome resistance to mTorKIs thus may be an effective additive therapy for treatment of patient with renal cell carcinoma or colorectal cancer.

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WYE-687

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