sbc-115076
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- $18 - $2500
- Product name: sbc-115076
- CAS: 489415-96-5
- MF: C31H33N3O5
- MW: 527.61
- EINECS:604-604-1
- MDL Number:MFCD03296540
- Synonyms:sbc-115076;4-[hydroxy-(3-methyl-4-phenylmethoxyphenyl)methylidene]-1-(3-morpholin-4-ylpropyl)-5-pyridin-4-ylpyrrolidine-2,3-dione;1,5-Dihydro-3-hydroxy-4-[3-methyl-4-(phenylmethoxy)benzoyl]-1-[3-(4-morpholinyl)propyl]-5-(4-pyridinyl)-2H-pyrrol-2-one;2H-Pyrrol-2-one, 1,5-dihydro-3-hydroxy-4-[3-methyl-4-(phenylmethoxy)benzoyl]-1-[3-(4-morpholinyl)propyl]-5-(4-pyridinyl)-;CS-1638;CS-2068;SBC-115076;SBC 115076;SBC115076;4-(4-(benzyloxy)-3-methylbenzoyl)-3-hydroxy-1-(3-morpholinopropyl)-5-(pyridin-4-yl)-1,5-dihydro-2H-pyrrol-2-one
58 prices
Selected condition:
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- ApexBio Technology
- Arctom
- Biosynth
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
- Sigma-Aldrich
- TRC
Package
- 10.00mg
- 10mM(1mLinDMSO)
- 10mM*1mLinDMSO(Solution)
- 25.00mg
- 50.00mg
- 50mg
- 100mg
- 1mg
- 5mg
- 10mg
- 250MG
- 10mM*1mLinDMSO(Solid+Solvent)
- 25mg
- 1G
- Manufactureraablocks
- Product numberAA00DB6E
- Product descriptionSBC-115076 99%
- Packaging5mg
- Price$38
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00DB6E
- Product descriptionSBC-115076 99%
- Packaging10mg
- Price$56
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00DB6E
- Product descriptionSBC-115076 99%
- Packaging1mg
- Price$18
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00DB6E
- Product descriptionSBC-115076 99%
- Packaging25mg
- Price$95
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberO32855
- Product descriptionSBC-115076 98%
- Packaging250MG
- Price$690
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberO32855
- Product descriptionSBC-115076 98%
- Packaging1G
- Price$2070
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product number3361CP
- Product descriptionCID5734410
- Packaging5mg
- Price$226
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB5907
- Product descriptionSBC-115076
- Packaging25mg
- Price$308
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB5907
- Product descriptionSBC-115076
- Packaging5mg
- Price$79
- Updated2026-05-06
- Buy
- ManufacturerArctom
- Product numberHY-12402
- Product descriptionSBC-115076 99.28%
- Packaging5mg
- Price$95
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-12402
- Product descriptionSBC-115076 99.28%
- Packaging10mM*1mLinDMSO(Solid+Solvent)
- Price$110
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-12402
- Product descriptionSBC-115076 99.28%
- Packaging10mM*1mLinDMSO(Solution)
- Price$110
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberSLK-S7976
- Product descriptionSBC-115076 99.79%
- Packaging25mg
- Price$361
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberSLK-S7976
- Product descriptionSBC-115076 99.79%
- Packaging5mg
- Price$121
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-12402
- Product descriptionSBC-115076 99.28%
- Packaging10mg
- Price$126
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberSLK-S7976
- Product descriptionSBC-115076 99.79%
- Packaging10mM(1mLinDMSO)
- Price$162
- Updated2026-05-26
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00DB6E | SBC-115076 99% | 5mg | $38 | 2026-05-28 | Buy |
| aablocks | AA00DB6E | SBC-115076 99% | 10mg | $56 | 2026-05-28 | Buy |
| aablocks | AA00DB6E | SBC-115076 99% | 1mg | $18 | 2026-05-28 | Buy |
| aablocks | AA00DB6E | SBC-115076 99% | 25mg | $95 | 2026-05-28 | Buy |
| ACHEMBLOCK | O32855 | SBC-115076 98% | 250MG | $690 | 2026-05-27 | Buy |
| ACHEMBLOCK | O32855 | SBC-115076 98% | 1G | $2070 | 2026-05-27 | Buy |
| AK Scientific | 3361CP | CID5734410 | 5mg | $226 | 2021-12-16 | Buy |
| ApexBio Technology | B5907 | SBC-115076 | 25mg | $308 | 2026-05-06 | Buy |
| ApexBio Technology | B5907 | SBC-115076 | 5mg | $79 | 2026-05-06 | Buy |
| Arctom | HY-12402 | SBC-115076 99.28% | 5mg | $95 | 2026-05-26 | Buy |
| Arctom | HY-12402 | SBC-115076 99.28% | 10mM*1mLinDMSO(Solid+Solvent) | $110 | 2026-05-26 | Buy |
| Arctom | HY-12402 | SBC-115076 99.28% | 10mM*1mLinDMSO(Solution) | $110 | 2026-05-26 | Buy |
| Arctom | SLK-S7976 | SBC-115076 99.79% | 25mg | $361 | 2026-05-26 | Buy |
| Arctom | SLK-S7976 | SBC-115076 99.79% | 5mg | $121 | 2026-05-26 | Buy |
| Arctom | HY-12402 | SBC-115076 99.28% | 10mg | $126 | 2026-05-26 | Buy |
| Arctom | SLK-S7976 | SBC-115076 99.79% | 10mM(1mLinDMSO) | $162 | 2026-05-26 | Buy |
Properties
Boiling point :754.2±60.0 °C(Predicted)
Density :1.266±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :DMSO:46.0(Max Conc. mg/mL);87.18(Max Conc. mM)
DMSO:PBS (pH 7.2) (1:1):0.5(Max Conc. mg/mL);0.95(Max Conc. mM)
DMF:2.0(Max Conc. mg/mL);3.79(Max Conc. mM) form :A crystalline solid
pka :4.50±1.00(Predicted)
color :White to off-white
SMILES :CC1=CC(C(C(C(C2=CC=NC=C2)N3CCCN4CCOCC4)=C(O)C3=O)=O)=CC=C1OCC5=CC=CC=C5
Density :1.266±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :DMSO:46.0(Max Conc. mg/mL);87.18(Max Conc. mM)
DMSO:PBS (pH 7.2) (1:1):0.5(Max Conc. mg/mL);0.95(Max Conc. mM)
DMF:2.0(Max Conc. mg/mL);3.79(Max Conc. mM) form :A crystalline solid
pka :4.50±1.00(Predicted)
color :White to off-white
SMILES :CC1=CC(C(C(C(C2=CC=NC=C2)N3CCCN4CCOCC4)=C(O)C3=O)=O)=CC=C1OCC5=CC=CC=C5
Safety Information
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| Signal word: | Warning | ||||||||||||||||||||||||||||||||
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Description
Proprotein convertase subtilisin kexin 9 (PCSK9) is a member of the subtilisin serine protease family with important roles in lipoprotein metabolism. PCSK9 overexpression in wild-type mice doubles plasma total cholesterol, possibly through acceleration of degradation of the LDL receptor (LDLR). SBC-115076 is an inhibitor of PCSK9 action that blocks LDLR degradation in HEK293T cells expressing PCSK9. Through this mechanism, submicromolar concentrations of SBC-115076 increase the uptake of LDL by liver cells in vitro. SBC-115076 is effective in vivo, lowering cholesterol levels in mice that are fed a high fat diet.Suppliers and manufacturers
ATK CHEMICAL COMPANY LIMITED
Career Henan Chemica Co
InvivoChem
Hangzhou MolCore BioPharmatech Co.,Ltd.
ShenZhen Trendseen Biological Technology Co.,Ltd.
Wuhan Topule Biopharmaceutical Co., Ltd
Aladdin Scientific
Amadis Chemical Company Limited
Shanghai Boyle Chemical Co., Ltd.




