SQ-31765

SQ-31765 Suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Products Intro: Product Name:SQ-31765；SQ31765;SQ 31765
CAS:138383-07-0
Purity:98.00% Package:100 mg；500 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354;
Email: support@targetmol.com
Products Intro: Product Name:SQ-31765
CAS:138383-07-0
Package:100mg;2800USD|50mg;2180USD|25mg;1670USD
Company Name: TargetMol Chemicals Inc.
Tel: +17819995354
Email: marketing@targetmol.com
Products Intro: Product Name:SQ-31765
CAS:138383-07-0
Package:100mg;2800USD|50mg;2180USD|25mg;1670USD
Company Name: Fan De(Beijing) Biotechnology Co., Ltd.  
Tel: 15911056312
Email: liming@bio-fount.com
Products Intro: Product Name:SQ-31765
CAS:138383-07-0
Purity:97.0% Package:5mg
Company Name: cjbscvictory  
Tel: 13348960310 13348960310
Email: 3003867561@qq.com
Products Intro: Product Name:SQ-31765
CAS:138383-07-0
Purity:98% Package:5mg；10mg；20mg；50mg；100mg；200mg

SQ-31765 manufacturers

  • SQ-31765
  • SQ-31765 pictures
  • $2800.00
  • 2026-04-20
  • CAS:138383-07-0
  • Purity:
  • Supply Ability: 10g
  • SQ-31765
  • SQ-31765 pictures
  • $2800.00
  • 2025-07-21
  • CAS:138383-07-0
  • Purity:
  • Supply Ability: 10g
SQ-31765 Basic information
Product Name:SQ-31765
Synonyms:2H-1-Benzazepin-2-one, 3-(acetyloxy)-1-[2-(dimethylamino)ethyl]-1,3,4,5-tetrahydro-4-(4-methoxyphenyl)-6-(trifluoromethyl)-, (3R,4S)-;SQ31765,SQ 31765;3-(Acetyloxy)-1-(2-(dimethylamino)ethyl)-1,3,4,5-tetrahydro-4-(4-methoxyphenyl)-6-(trifluromethyl)-2H-1-benzazepine-2-one
CAS:138383-07-0
MF:C24H27F3N2O4
MW:464.48
EINECS:
Product Categories:
Mol File:138383-07-0.mol
SQ-31765 Structure
SQ-31765 Chemical Properties
storage temp. Store at -20°C
solubility Soluble in DMSO
Safety Information
MSDS Information
SQ-31765 Usage And Synthesis
UsesSQ-31765 is a benzazepine calcium channel blocker.
in vivo

SQ-31765 (SQ 31,765) can reduce the severity of ischemia in a manner which is independent of changes in myocardial blood flow or hemodynamic alterations. Anesthetized dogs are given saline (n=6), SQ-31765 (n=6; 0.2 mg/kg) or SQ 32,189 (n=6; 0.2 mg/kg) i.v. 10 min before ischemia. The effect on pacing-induced ST-segment elevation (pacing+left anterior descending coronary artery stenosis) and myocardial blood flow are determined. SQ-31765 reduces ST-elevation (P<0.05) compared to saline at 10, 40 and 70 min after infusion (5.9±1.4 and 12.0±1.4 mV, respectively, at 70 min). Left anterior descending coronary artery stenosis during atrial pacing resulted in a significant reduction in subendocardial flow in all groups before drug infusion (41±7, 44±7 and 35±9 mL/min/100 g for saline, SQ-31765 and SQ 32,189, respectively)[1].

References[1] Grover GJ, et al. Anti-ischemic and vasorelaxant effects of the new benzazepine calcium channel blocker SQ 31,765. J Pharmacol Exp Ther. 1989 Dec;251(3):1020-5. PMID:2481028
SQ-31765 Preparation Products And Raw materials
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