SQ-31765 NEW
| Price | $1670 | $2180 | $2800 |
| Package | 25mg | 50mg | 100mg |
| Supply Ability: | 10g |
| Update Time: | 2026-04-20 |
Product Details
| Product Name: SQ-31765 | CAS No.: 138383-07-0 |
| Supply Ability: 10g | Release date: 2026/04/20 |
Product Introduction
Bioactivity
| Name | SQ-31765 |
| Description | SQ-31765 is a blocker of benzazepine calcium channel. |
| In vivo | SQ-31765 (SQ 31,765) effectively mitigates ischemia severity independent of myocardial blood flow or hemodynamic changes. In a study, anesthetized dogs were administered saline (n=6), SQ-31765 (n=6; 0.2 mg/kg), or SQ 32,189 (n=6; 0.2 mg/kg) intravenously 10 minutes before inducing ischemia. The study examined the compound's impact on pacing-induced ST-segment elevation and myocardial blood flow during left anterior descending coronary artery stenosis. SQ-31765 significantly reduced ST-segment elevation (P<0.05) at 10, 40, and 70 minutes post-infusion, showing a notable reduction (5.9±1.4 mV at 70 minutes) compared to the saline group (12.0±1.4 mV at 70 minutes). All test groups exhibited decreased subendocardial flow due to left anterior descending coronary artery stenosis during atrial pacing before drug administration, highlighting SQ-31765's protective effects against pacing-induced myocardial injury. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Keywords | SQ-31765 | SQ31765 | SQ 31765 | CalciumChannel | Calcium Channel |
| Inhibitors Related | Quadrol | Tricaine methanesulfonate | Nisoldipine | 2,4,6-Tri-tert-butylphenol | Chlorocresol | L-Ascorbic acid | L-Phenylalanine | L-Ascorbic acid sodium salt | 2-Nitrobenzoic acid | Magnesium Chloride Hexahydrate | Magnesium sulfate | Cinchonine |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
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