SQ-31765 NEW
| Price | $1670 | $2180 | $2800 |
| Package | 25mg | 50mg | 100mg |
| Supply Ability: | 10g |
| Update Time: | 2025-07-21 |
Product Details
| Product Name: SQ-31765 | CAS No.: 138383-07-0 |
| Supply Ability: 10g | Release date: 2025/07/21 |
Product Introduction
Bioactivity
| Name | SQ-31765 |
| Description | SQ-31765 is a blocker of benzazepine calcium channel. |
| In vivo | SQ-31765 (SQ 31,765) effectively mitigates ischemia severity independent of myocardial blood flow or hemodynamic changes. In a study, anesthetized dogs were administered saline (n=6), SQ-31765 (n=6; 0.2 mg/kg), or SQ 32,189 (n=6; 0.2 mg/kg) intravenously 10 minutes before inducing ischemia. The study examined the compound's impact on pacing-induced ST-segment elevation and myocardial blood flow during left anterior descending coronary artery stenosis. SQ-31765 significantly reduced ST-segment elevation (P<0.05) at 10, 40, and 70 minutes post-infusion, showing a notable reduction (5.9±1.4 mV at 70 minutes) compared to the saline group (12.0±1.4 mV at 70 minutes). All test groups exhibited decreased subendocardial flow due to left anterior descending coronary artery stenosis during atrial pacing before drug administration, highlighting SQ-31765's protective effects against pacing-induced myocardial injury. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Keywords | SQ-31765 | SQ31765 | SQ 31765 | CalciumChannel | Calcium channel | Calcium Channel |
| Inhibitors Related | Nisoldipine | Nimodipine | Diltiazem hydrochloride | Levetiracetam | L-Ascorbic acid | Lanthanum(III) chloride heptahydrate | Ethyl cinnamate | 1-Octanol | 2-Nitrobenzoic acid | 1,2,4-Trihydroxybenzene | Methyl homoveratrate | Otilonium bromide |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, USA
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