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Postion:Product Catalog >Biochemical Engineering>Biochemical Reagents>Agonist Inhibitors>CC-401
CC-401
  • CC-401

CC-401 NEW

Price $383 $1680 $2870
Package 1mg 5mg 10mg
Supply Ability: 10g
Update Time: 2026-04-22

Product Details

Product Name: CC-401 CAS No.: 395104-30-0
Supply Ability: 10g Release date: 2026/04/22

Product Introduction

Bioactivity

NameCC-401
DescriptionCC-401 is a specific inhibitor of JNK (Ki: 25-50nM).
In vitroCC-401 is a second-generation ATP-competitive inhibitor of all three forms of JNK. It is selective against JNK over other kinases such as p38, ERK, IKK2, and ZAP70. CC-401 potently inhibits JNK in cell-based assay with a concentration of 1 to 5μM. The activation of JNK signaling is identified in many immune-mediated kidney disease models. Thus, as the JNK inhibitor, CC-401 is found to be effective in these renal injury models. In the acute anti-GBM disease, CC-401 inhibits JNK activation and causes a 50%-70% reduction of proteinuria. In addition, CC-401 is also used in liver injury models [1][2][3].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility InformationDMSO : ≥19.4 mg/mL, Sonication is recommended.
KeywordsCC-401 | CC401 | CC 401
Inhibitors RelatedAstragaloside IV | Teneligliptin hydrobromide | Berberine hydrogen sulphate | SP600125 | Chloranil | (-)-Bornyl acetate | Benzbromarone | Anisomycin | Chloramphenicol | Metacetamol | Berberine sulfate | Benzyl salicylate

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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TargetMol Chemicals Inc.

6YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, MA
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