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Postion:Product Catalog >DC0-NH2
DC0-NH2
  • DC0-NH2

DC0-NH2 NEW

Price $1520 $1980 $2500
Package 25mg 50mg 100mg
Supply Ability: 10g
Update Time: 2026-05-26

Product Details

Product Name: DC0-NH2 CAS No.: 615538-51-7
Supply Ability: 10g Release date: 2026/05/26

Product Introduction

Bioactivity

NameDC0-NH2
DescriptionThe cytotoxicity of DC0-NH2 is 1000 times that of commonly used anti-cancer drugs (such as doxorubicin). It is the effect part of ADC. It is a simplified simulation of DC1 and has better stability. DC0-NH2 can bind to the small groove of DNA, and then adenine residue is alkylated by its propabenzindole (CBI) component.
In vitroDC0-NH2 (0-3 nM; 72 hours), in the vitality test of breast cancer cell lines, has a high anti-proliferative effect on Ramos, Namalwa and HL60 / s cells, inhibits the proliferation of Namalwa and HL60 / s cells The IC50 values were 7 pM and 5 pM, respectively, and the inhibition range of COLO205 cells was within 100 pM.
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
KeywordsDC0-NH2 | DC-0-NH2 | DC0NH2 | DC0 NH2 | ADCCytotoxin | ADC Cytotoxin
Inhibitors RelatedMethotrexate | Mertansine | Doxorubicin hydrochloride | Exatecan | Methotrexate disodium | Camptothecin | Dexamethasone acetate | SN-38 | Dexamethasone | Fluticasone (propionate) | Paclitaxel | Exatecan Mesylate

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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4YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, USA
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