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Postion:Product Catalog >DC0-NH2
DC0-NH2
  • DC0-NH2

DC0-NH2 NEW

Price $1520 $1980 $2500
Package 25mg 50mg 100mg
Supply Ability: 10g
Update Time: 2025-07-20

Product Details

Product Name: DC0-NH2 CAS No.: 615538-51-7
Supply Ability: 10g Release date: 2025/07/20

Product Introduction

Bioactivity

NameDC0-NH2
DescriptionThe cytotoxicity of DC0-NH2 is 1000 times that of commonly used anti-cancer drugs (such as doxorubicin). It is the effect part of ADC. It is a simplified simulation of DC1 and has better stability. DC0-NH2 can bind to the small groove of DNA, and then adenine residue is alkylated by its propabenzindole (CBI) component.
In vitroDC0-NH2 (0-3 nM; 72 hours), in the vitality test of breast cancer cell lines, has a high anti-proliferative effect on Ramos, Namalwa and HL60 / s cells, inhibits the proliferation of Namalwa and HL60 / s cells The IC50 values were 7 pM and 5 pM, respectively, and the inhibition range of COLO205 cells was within 100 pM.
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
KeywordsDC0-NH2 | DC-0-NH2 | DC0NH2 | DC0 NH2 | ADCCytotoxin | ADC Cytotoxin
Inhibitors RelatedMethotrexate | Mertansine | Doxorubicin hydrochloride | Daunorubicin hydrochloride | Exatecan | Camptothecin | Methotrexate disodium | Dexamethasone | Fluticasone (propionate) | Paclitaxel | Budesonide | Exatecan Mesylate

Company Profile Introduction

TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds. 170+ Compound Libraries, 10000+ Noval Small Molecucles,16000+ Nature Compounds TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.

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TargetMol Chemicals Inc.

2YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
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