DC0-NH2 NEW
| Price | $1520 | $1980 | $2500 |
| Package | 25mg | 50mg | 100mg |
| Supply Ability: | 10g |
| Update Time: | 2026-05-27 |
Product Details
| Product Name: DC0-NH2 | CAS No.: 615538-51-7 |
| Supply Ability: 10g | Release date: 2026/05/27 |
Product Introduction
Bioactivity
| Name | DC0-NH2 |
| Description | The cytotoxicity of DC0-NH2 is 1000 times that of commonly used anti-cancer drugs (such as doxorubicin). It is the effect part of ADC. It is a simplified simulation of DC1 and has better stability. DC0-NH2 can bind to the small groove of DNA, and then adenine residue is alkylated by its propabenzindole (CBI) component. |
| In vitro | DC0-NH2 (0-3 nM; 72 hours), in the vitality test of breast cancer cell lines, has a high anti-proliferative effect on Ramos, Namalwa and HL60 / s cells, inhibits the proliferation of Namalwa and HL60 / s cells The IC50 values were 7 pM and 5 pM, respectively, and the inhibition range of COLO205 cells was within 100 pM. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Keywords | DC0-NH2 | DC-0-NH2 | DC0NH2 | DC0 NH2 | ADCCytotoxin | ADC Cytotoxin |
| Inhibitors Related | Methotrexate | Mertansine | Doxorubicin hydrochloride | Exatecan | Methotrexate disodium | Camptothecin | Dexamethasone acetate | SN-38 | Dexamethasone | Fluticasone (propionate) | Paclitaxel | Exatecan Mesylate |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
Recommended supplier
| Product name | Price | Suppliers | Update time | |
|---|---|---|---|---|
| $2.00 |
VIP1Y
|
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
|
2026-04-17 | |
| $99.00 |
VIP4Y
|
TargetMol Chemicals Inc.
|
2026-05-11 | |
|
VIP1Y
|
Hefei Lbao Physical & Chemical Science Co.,Ltd
|
2026-05-18 | ||
| $1520.00 |
VIP4Y
|
TargetMol Chemicals Inc.
|
2026-05-26 |
United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
INQUIRY