Product Details
| Product Name:
GNE-955 |
CAS No.:
1527523-39-2 |
| Supply Ability:
10g |
Release date:
2026/05/11 |
Product Introduction
Bioactivity
| Name | GNE-955 |
| Description | GNE-955 is a potent and orally active inhibitor of pan Pim kinase, with inhibition constants (Kis) of 0.018 nM, 0.11 nM, and 0.08 nM for Pim1, Pim2, and Pim3, respectively. |
| In vitro | GNE-955 inhibits the proliferation of MM.1S cells (IC50: 0.5 μM) after 72 hours of treatment and inhibits the phosphorylation of BAD (s112), S6 (s235/236), S6 (s240/244), and 4EBP (s65) within the range of 0.156-5 μM, with no effect on total BAD, S6, or 4EBP protein levels. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Shipping with blue ice/Shipping at ambient temperature. |
| Keywords | PIM3 | PIM2 | PIM1 | GNE-955 | GNE955 | GNE 955 |
| Inhibitors Related | Hispidulin | TCS-PIM-1-4a | SGI-1776 | CK2/ERK8-IN-1 | M-110 | NSC756093 | Pim-1 kinase inhibitor 4 | AZD1208 | Pim-1/2 kinase inhibitor 1 | Pim-1 kinase inhibitor 8 | TP-3654 | K00135 |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries, 10000+ Noval Small Molecucles,16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
You may like
-
CAS:1199590-75-4
$3400.00
-
CAS:1698900-69-4
$1670.00
-
CAS:1199590-75-4
$3390.00
Recommended supplier
| Product name |
Price |
|
Suppliers |
Update time |
|
|
$56.00
|
VIP6Y
|
TargetMol Chemicals Inc.
|
2026-06-02 |
|
|
$1790.00
|
VIP4Y
|
TargetMol Chemicals Inc.
|
2026-05-11 |
|
|
$1.00
|
VIP7Y
|
Career Henan Chemical Co
|
2019-12-24 |