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Postion:Product Catalog >GNE-955
GNE-955
  • GNE-955

GNE-955 NEW

Price $1970 $2580 $3400
Package 25mg 50mg 100mg
Supply Ability: 10g
Update Time: 2026-05-11

Product Details

Product Name: GNE-955 CAS No.: 1527523-39-2
Supply Ability: 10g Release date: 2026/05/11

Product Introduction

Bioactivity

NameGNE-955
DescriptionGNE-955 is a potent and orally active inhibitor of pan Pim kinase, with inhibition constants (Kis) of 0.018 nM, 0.11 nM, and 0.08 nM for Pim1, Pim2, and Pim3, respectively.
In vitroGNE-955 inhibits the proliferation of MM.1S cells (IC50: 0.5 μM) after 72 hours of treatment and inhibits the phosphorylation of BAD (s112), S6 (s235/236), S6 (s240/244), and 4EBP (s65) within the range of 0.156-5 μM, with no effect on total BAD, S6, or 4EBP protein levels.
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
KeywordsPIM3 | PIM2 | PIM1 | GNE-955 | GNE955 | GNE 955
Inhibitors RelatedHispidulin | TCS-PIM-1-4a | SGI-1776 | CK2/ERK8-IN-1 | M-110 | NSC756093 | Pim-1 kinase inhibitor 4 | AZD1208 | Pim-1/2 kinase inhibitor 1 | Pim-1 kinase inhibitor 8 | TP-3654 | K00135

Company Profile Introduction

TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds. 170+ Compound Libraries, 10000+ Noval Small Molecucles,16000+ Nature Compounds TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.

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TargetMol Chemicals Inc.

2YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
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