產(chǎn)品屬性：
產(chǎn)品名稱 | 規(guī)格 | CAS號(hào) | 型號(hào) |
(R)-(+)-Etomoxir sodium salt | 10mM (in 1mL DMSO) 10mg 50mg 500mg 1g | 828934-41-4 | EY-Y0165199 |
Cas No.828934-41-4
別名 N/A
化學(xué)名 sodium (R)-2-(6-(4-chlorophenoxy)hexyl)oxirane-2-carboxylate
分子式 C15H18ClNaO4
分子量 320.74
溶解度 ≥ 12mg/mL in DMSO
儲(chǔ)存條件 Store at -20°C
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述：
Etomoxir sodium salt ((R)-(+)-Etomoxir sodium salt) is an irreversible inhibitor of carnitine palmitoyltransferase 1a (CPT-1a), inhibits fatty acid oxidation (FAO) through CPT-1a and inhibits palmitate β-oxidation in human, rat and guinea pig.
References:
[1]. Agius L, et al. Differences between human, rat and guinea pig hepatocyte cultures. A comparative study of their rates of beta-oxidation and esterification of palmitate and their sensitivity to R-etomoxir. Biochem Pharmacol. 1991 Oct 9;42(9):1711-5.
[2]. O'Connor RS, et al. The CPT1a inhibitor, etomoxir induces severe oxidative stress at commonly used concentrations. Sci Rep. 2018 Apr 19;8(1):6289.
關(guān)鍵字： 828934-41-4;C15H18ClNaO4;(R)-(+)-Etomoxir sod;
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