一二三四区视频,亚洲少妇熟女色,日本久热无码视频网,欧美国产日韩大尺度,亚洲a视频,久久少妇一区二区,日韩999无码视频,刺激久久久久久久,啊啊啊啊不要啊在线

ChemicalBook >> journal list >> Frontiers in Physiology >>article
Frontiers in Physiology

Frontiers in Physiology

IF: 3.2
Download PDF

Uridine and its role in metabolic diseases, tumors, and neurodegenerative diseases

Published:29 February 2024 DOI: 10.3389/fphys.2024.1360891
Yueyuan Yang, Yahong Ye, Yingfeng Deng, Ling Gao

Abstract

Uridine is a pyrimidine nucleoside found in plasma and cerebrospinal fluid with a concentration higher than the other nucleosides. As a simple metabolite, uridine plays a pivotal role in various biological processes. In addition to nucleic acid synthesis, uridine is critical to glycogen synthesis through the formation of uridine diphosphate glucose in which promotes the production of UDP-GlcNAc in the hexosamine biosynthetic pathway and supplies UDP-GlcNAc for O-GlcNAcylation. This process can regulate protein modification and affect its function. Moreover, Uridine has an effect on body temperature and circadian rhythms, which can regulate the metabolic rate and the expression of metabolic genes. Abnormal levels of blood uridine have been found in people with diabetes and obesity, suggesting a link of uridine dysregulation and metabolic disorders. At present, the role of uridine in glucose metabolism and lipid metabolism is controversial, and the mechanism is not clear, but it shows the trend of long-term damage and short-term benefit. Therefore, maintaining uridine homeostasis is essential for maintaining basic functions and normal metabolism. This article summarizes the latest findings about the metabolic effects of uridine and the potential of uridine metabolism as therapeutic target in treatment of metabolic disorders.

Substances (3)

Related products
Procduct Name CAS Molecular Formula Supplier Price
Uridine 58-96-8 C9H12N2O6 940 suppliers $5.00-$37700.00
UDP-ALPHA-D-N-ACETYLGLUCOSAMINE, DISODIUM SALT 91183-98-1 C17H28N3NaO17P2 153 suppliers $28.00-$1880.00
Uridine 5'-(trihydrogen diphosphate), mono-alpha-d-glucopyranosyl ester 133-89-1 C15H24N2O17P2 58 suppliers Inquiry

Similar articles

IF:5.4

Inosine in Neurodegenerative Diseases: From the Bench to the Bedside.

ACS Applied Energy Materials Maria Sofia Basile, Placido Bramanti,etc Published: 21 July 2022
IF:4.6

Uridine Metabolism and Its Role in Glucose, Lipid, and Amino Acid Homeostasis.

ACS Applied Bio Materials Yumei Zhang,?Songge Guo,etc Published: 14 April 2020
IF:0

The role of thymidine kinase in cancer diseases.

Expert opinion on medical diagnostics Ondrej Topolcan, Lubos Holubec,etc Published: 1 February 2008
平泉县| 临洮县| 剑川县| 文山县| 拜城县| 沂南县| 资溪县| 清新县| 灵台县| 盐亭县| 颍上县| 南安市| 东乌珠穆沁旗| 永清县| 宁乡县| 牙克石市| 兴隆县| 象州县| 阿拉善右旗| 南陵县| 新民市| 华宁县| 惠安县| 紫金县| 金寨县| 秭归县| 藁城市| 易门县| 外汇| 荆门市| 和林格尔县| 旬邑县| 高雄县| 陈巴尔虎旗| 文水县| 江口县| 天长市| 琼结县| 竹北市| 温泉县| 凤山县|