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Cell Death & Disease
Cell Death & Disease
IF:8.1
CiteScore:15.1
Articles:935
Brought to readers by the editorial team of Cell Death & Differentiation, Cell Death & Disease is an online peer-reviewed journal specializing in translational cell death research. It covers a wide range of topics in experimental and internal medicine, including cancer, immunity, neuroscience, and now cancer metabolism.
Cell Death & Disease seeks to encompass the breadth of translational implications of cell death, and topics of particular concentration will include, but are not limited to, the following:
Experimental medicine
Cancer
Immunity
Internal medicine
Neuroscience
Cancer metabolism
Transcription factor ATMIN facilitates chemoresistance in nasopharyngeal carcinoma
Published: 6 February 2024
DOI: 10.1038/s41419-024-06496-x
Xue-Liang Fang,?Qing-Jie Li,?Jia-Yi Lin,?Cheng-Long Huang,?Sheng-Yan Huang,?Xi-Rong Tan,?Shi-Wei He,?Xun-Hua Zhu,?Jun-Yan Li,?Sha Gong,?Han Qiao,?Ying-Qin Li,?Na Liu,?Jun Ma,?Yin Zhao,?Ling-Long Tang
Xue-Liang Fang,?Qing-Jie Li,?Jia-Yi Lin,?Cheng-Long Huang,?Sheng-Yan Huang,?Xi-Rong Tan,?Shi-Wei He,?Xun-Hua Zhu,?Jun-Yan Li,?Sha Gong,?Han Qiao,?Ying-Qin Li,?Na Liu,?Jun Ma,?Yin Zhao,?Ling-Long Tang
AURKA inhibition induces Ewing’s sarcoma apoptosis and ferroptosis through NPM1/YAP1 axis
Published: 29 January 2024
DOI: 10.1038/s41419-024-06485-0
Huimou Chen,?Jing Hu,?Xilin Xiong,?Hongling Chen,?Biaojun Lin,?Yusong Chen,?Yang Li,?Di Cheng,?Zhihua Li
Huimou Chen,?Jing Hu,?Xilin Xiong,?Hongling Chen,?Biaojun Lin,?Yusong Chen,?Yang Li,?Di Cheng,?Zhihua Li
RUNX1/NPM1/H3K4me3 complex contributes to extracellular matrix remodeling via enhancing FOSL2 transcriptional activation in glioblastoma
Published: 29 January 2024
DOI: 10.1038/s41419-024-06481-4
Xiaoteng Cui,?Dawei Huo,?Qixue Wang,?Yunfei Wang,?Xiaomin Liu,?Kai Zhao,?Yongping You,?Junxia Zhang,?Chunsheng Kang
Xiaoteng Cui,?Dawei Huo,?Qixue Wang,?Yunfei Wang,?Xiaomin Liu,?Kai Zhao,?Yongping You,?Junxia Zhang,?Chunsheng Kang
Blockade of DDR1/PYK2/ERK signaling suggesting SH2 superbinder as a novel autophagy inhibitor for pancreatic cancer
Published: 9 December 2023
DOI: 10.1038/s41419-023-06344-4
Hui Xu, Ming Tan, Guo-Qing Hou, Ya-Zhou Sang, Li Lin, Xiao-Cai Gan, Xuan Cao, An-Dong Liu
Hui Xu, Ming Tan, Guo-Qing Hou, Ya-Zhou Sang, Li Lin, Xiao-Cai Gan, Xuan Cao, An-Dong Liu
Carboxypeptidase A4 negatively regulates HGS-ETR1/2-induced pyroptosis by forming a positive feedback loop with the AKT signalling pathway
Published: 4 December 2023
DOI: 10.1038/s41419-023-06327-5
Luoling Wang,?Rilin Deng,?Shuishun Chen,?Renyun Tian,?Mengmeng Guo,?Zihao Chen,?Yingdan Zhang,?Huiyi Li,?Qian Liu,?Songqing Tang,?Haizhen Zhu
Luoling Wang,?Rilin Deng,?Shuishun Chen,?Renyun Tian,?Mengmeng Guo,?Zihao Chen,?Yingdan Zhang,?Huiyi Li,?Qian Liu,?Songqing Tang,?Haizhen Zhu
Potentiation of apoptosis in drug-resistant mantle cell lymphoma cells by MCL-1 inhibitor involves downregulation of inhibitor of apoptosis proteins.
Published: 2 November 2023
DOI: 10.1038/s41419-023-06233-w
Yijing Li, Heng-Huan Lee, Vivian Changying Jiang, Yuxuan Che, Joseph McIntosh, Alexa Jordan, Jovanny Vargas, Tianci Zhang, Fangfang Yan, Margaret Elizabeth Simmons, Wei Wang, Lei Nie, Yixin Yao, Preetesh Jain, Michael Wang, Yang Liu
Yijing Li, Heng-Huan Lee, Vivian Changying Jiang, Yuxuan Che, Joseph McIntosh, Alexa Jordan, Jovanny Vargas, Tianci Zhang, Fangfang Yan, Margaret Elizabeth Simmons, Wei Wang, Lei Nie, Yixin Yao, Preetesh Jain, Michael Wang, Yang Liu
EIF4A3-mediated circ_0042881 activates the RAS pathway via miR-217/SOS1 axis to facilitate breast cancer progression.
Published: 25 August 2023
DOI: 10.1038/s41419-023-06085-4
Chenxi Ju, Mingxia Zhou, Dan Du, Chang Wang, Jieqiong Yao, Hongle Li, Yang Luo, Fucheng He, Jing He
Chenxi Ju, Mingxia Zhou, Dan Du, Chang Wang, Jieqiong Yao, Hongle Li, Yang Luo, Fucheng He, Jing He
N 6 -methyladenosine modification of REG1α facilitates colorectal cancer progression via β-catenin/MYC/LDHA axis mediated glycolytic reprogramming.
Published: 25 August 2023
DOI: 10.1038/s41419-023-06067-6
Mingxia Zhou, Jing He, Yingxia Li, Libin Jiang, Jiaxuan Ran, Chang Wang, Chenxi Ju, Dan Du, Xinyu Xu, Xuexin Wang, Hongle Li, Fucheng He, Hongtao Wen
Mingxia Zhou, Jing He, Yingxia Li, Libin Jiang, Jiaxuan Ran, Chang Wang, Chenxi Ju, Dan Du, Xinyu Xu, Xuexin Wang, Hongle Li, Fucheng He, Hongtao Wen
Bcl-2 family inhibitors sensitize human cancer models to therapy
Published: 17 July 2023
DOI: 10.1038/s41419-023-05963-1
Elisabetta Valentini, Marta Di Martile, Matteo Brignone, Marica Di Caprio, Isabella Manni, Michela Chiappa, Ilaria Sergio, Martina Chiacchiarini, Chiara Bazzichetto, Fabiana Conciatori, Simona D'Aguanno, Carmen D'Angelo, Rino Ragno, Michelangelo Russillo, Gianni Colotti, Francesco Marchesi, Maria Laura Bellone, Fabrizio Dal Piaz, Maria Pia Felli, Giovanna Damia, Donatella Del Bufalo
Elisabetta Valentini, Marta Di Martile, Matteo Brignone, Marica Di Caprio, Isabella Manni, Michela Chiappa, Ilaria Sergio, Martina Chiacchiarini, Chiara Bazzichetto, Fabiana Conciatori, Simona D'Aguanno, Carmen D'Angelo, Rino Ragno, Michelangelo Russillo, Gianni Colotti, Francesco Marchesi, Maria Laura Bellone, Fabrizio Dal Piaz, Maria Pia Felli, Giovanna Damia, Donatella Del Bufalo
Identification of RAC1 in promoting brain metastasis of lung adenocarcinoma using single-cell transcriptome sequencing
Published: 18 May 2023
DOI: 10.1038/s41419-023-05823-y
Mingyu Chen, Hanyue Li, Xiaolin Xu, Xunxia Bao, Lei Xue, Xinghao Ai, Jian Xu, Ming Xu, Yong Shi, Timing Zhen, Jie Li, Yi Yang, Yang Ji, Zhiliang Fu, Kaichen Xing, Tao Qing, Qiubo Wang, Ping Zhong, Sibo Zhu
Mingyu Chen, Hanyue Li, Xiaolin Xu, Xunxia Bao, Lei Xue, Xinghao Ai, Jian Xu, Ming Xu, Yong Shi, Timing Zhen, Jie Li, Yi Yang, Yang Ji, Zhiliang Fu, Kaichen Xing, Tao Qing, Qiubo Wang, Ping Zhong, Sibo Zhu
TLR7-MyD88-DC-CXCL16 axis results neutrophil activation to elicit inflammatory response in pustular psoriasis
Published: 9 May 2023
DOI: 10.1038/s41419-023-05815-y
Jiajing Lu, Xiaoyuan Zhong, Chunyuan Guo, Li Tang, Ning Yu, Chen Peng, Yangfeng Ding, Xunxia Bao, Jing Zhou, Yuling Shi
Jiajing Lu, Xiaoyuan Zhong, Chunyuan Guo, Li Tang, Ning Yu, Chen Peng, Yangfeng Ding, Xunxia Bao, Jing Zhou, Yuling Shi
BCR-ABL triggers a glucose-dependent survival program during leukemogenesis through the suppression of TXNIP
Published: 24 April 2023
DOI: 10.1038/s41419-023-05811-2
Lin Feng, Ruxin Ding, Xuan Qu, Yuanchun Li, Tong Shen, Lei Wang, Ruikai Li, Juan Zhang, Yi Ru, Xin Bu, Yang Wang, Min Li, Wenqi Song, Liangliang Shen, Pengxia Zhang
Lin Feng, Ruxin Ding, Xuan Qu, Yuanchun Li, Tong Shen, Lei Wang, Ruikai Li, Juan Zhang, Yi Ru, Xin Bu, Yang Wang, Min Li, Wenqi Song, Liangliang Shen, Pengxia Zhang
PRR15 deficiency facilitates malignant progression by mediating PI3K/Akt signaling and predicts clinical prognosis in triple-negative rather than non-triple-negative breast cancer
Published: 18 April 2023
DOI: 10.1038/s41419-023-05746-8
Fengzhu Guo, Jialu Ma, Cong Li, Shuning Liu, Weizheng Wu, Chunxiao Li, Jiani Wang, Jinsong Wang, Zhijun Li, Jingtong Zhai, Fangzhou Sun, Yantong Zhou, Changyuan Guo, Haili Qian, Binghe Xu
Fengzhu Guo, Jialu Ma, Cong Li, Shuning Liu, Weizheng Wu, Chunxiao Li, Jiani Wang, Jinsong Wang, Zhijun Li, Jingtong Zhai, Fangzhou Sun, Yantong Zhou, Changyuan Guo, Haili Qian, Binghe Xu
CYP1B1 inhibits ferroptosis and induces anti-PD-1 resistance by degrading ACSL4 in colorectal cancer.
Published: 14 April 2023
DOI: 10.1038/s41419-023-05803-2
Congcong Chen, Yabing Yang, Yanguan Guo, Jiashuai He, Zuyang Chen, Shenghui Qiu, Yiran Zhang, Hui Ding, Jinghua Pan, Yunlong Pan
Congcong Chen, Yabing Yang, Yanguan Guo, Jiashuai He, Zuyang Chen, Shenghui Qiu, Yiran Zhang, Hui Ding, Jinghua Pan, Yunlong Pan
Radiation induces IRAK1 expression to promote radioresistance by suppressing autophagic cell death via decreasing the ubiquitination of PRDX1 in glioma cells
Published: 8 April 2023
DOI: 10.1038/s41419-023-05732-0
Jing Li, Yuchen Sun, Xu Zhao, Yuan Ma, Yuchen Xie, Siqi Liu, Beina Hui, Xiaobo Shi, Xuanzi Sun, Xiaozhi Zhang
Jing Li, Yuchen Sun, Xu Zhao, Yuan Ma, Yuchen Xie, Siqi Liu, Beina Hui, Xiaobo Shi, Xuanzi Sun, Xiaozhi Zhang
Differential regulation of H3K9/H3K14 acetylation by small molecules drives neuron-fate-induction of glioma cell
Published: 20 February 2023
DOI: 10.1038/s41419-023-05611-8
Xincheng Liu, Cui Guo, Tiandong Leng, Zhen Fan, Jialuo Mai, Jiehong Chen, Jinhai Xu, Qianyi Li, Bin Jiang, Ke Sai, Wenzhuo Yang, Jiayu Gu, Jingyi Wang, Shuxin Sun, Zhijie Chen, Yingqian Zhong, Xuanming Liang, Chaoxin Chen, Jing Cai, Yuan Lin, Jiankai Liang, Jun Hu, Guangmei Yan, Wenbo Zhu, Wei Yin
Xincheng Liu, Cui Guo, Tiandong Leng, Zhen Fan, Jialuo Mai, Jiehong Chen, Jinhai Xu, Qianyi Li, Bin Jiang, Ke Sai, Wenzhuo Yang, Jiayu Gu, Jingyi Wang, Shuxin Sun, Zhijie Chen, Yingqian Zhong, Xuanming Liang, Chaoxin Chen, Jing Cai, Yuan Lin, Jiankai Liang, Jun Hu, Guangmei Yan, Wenbo Zhu, Wei Yin
PHB2 promotes colorectal cancer cell proliferation and tumorigenesis through NDUFS1-mediated oxidative phosphorylation
Published: 20 January 2023
DOI: 10.1038/s41419-023-05575-9
Lin Ren, Li Meng, Jing Gao, Mingdian Lu, Chengyu Guo, Yunyun Li, Ziye Rong, Yan Ye
Lin Ren, Li Meng, Jing Gao, Mingdian Lu, Chengyu Guo, Yunyun Li, Ziye Rong, Yan Ye
DDX17 induces epithelial-mesenchymal transition and metastasis through the miR-149-3p/CYBRD1 pathway in colorectal cancer
Published: 2 January 2023
DOI: 10.1038/s41419-022-05508-y
Gang Zhao,?Qijing Wang,?Yue Zhang,?Rui Gu,?Min Liu,?Qin Li,?Jie Zhang,?Hang Yuan,?Tianyu Feng,?Deqiong Ou,?Siqi Li,?Shan Li,?Kai Li,?Chunfen Mo,?Ping Lin
Gang Zhao,?Qijing Wang,?Yue Zhang,?Rui Gu,?Min Liu,?Qin Li,?Jie Zhang,?Hang Yuan,?Tianyu Feng,?Deqiong Ou,?Siqi Li,?Shan Li,?Kai Li,?Chunfen Mo,?Ping Lin
MYC and MET cooperatively drive hepatocellular carcinoma with distinct molecular traits and vulnerabilities
Published: 24 November 2022
DOI: 10.1038/s41419-022-05411-6
Celia Sequera, Margherita Grattarola, Agnes Holczbauer, Rosanna Dono, Stefania Pizzimenti, Giuseppina Barrera, Kirk J Wangensteen, Flavio Maina
Celia Sequera, Margherita Grattarola, Agnes Holczbauer, Rosanna Dono, Stefania Pizzimenti, Giuseppina Barrera, Kirk J Wangensteen, Flavio Maina
The oncoprotein MUC1 facilitates breast cancer progression by promoting Pink1-dependent mitophagy via ATAD3A destabilization
Published: 26 October 2022
DOI: 10.1038/s41419-022-05345-z
Quanfu Li, Yunkai Chu, Shengze Li, Liping Yu, Huayun Deng, Chunhua Liao, Xiaodong Liao, Chihyu Yang, Min Qi, Jinke Cheng, Guoqiang Chen, Lei Huang
Quanfu Li, Yunkai Chu, Shengze Li, Liping Yu, Huayun Deng, Chunhua Liao, Xiaodong Liao, Chihyu Yang, Min Qi, Jinke Cheng, Guoqiang Chen, Lei Huang