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Toxicology letters

IF:2.9 CiteScore:7.1 Articles:897

An international journal for the rapid publication of novel reports on a range of aspects of toxicology, especially mechanisms of toxicity.

Oxymatrine antagonises oxidative stress and apoptosis in Nemopilema nomurai toxin-induced cardiotoxicity by inhibiting mitogen-activated protein kinase

Published: 1 January 2025 DOI: 10.1016/j.toxlet.2024.12.004
Xinming Wang , Yongfang Wang , Xiaoyu Geng , Zengfa Wang , Jinyu Zhang , Tianwen Liu , Wei Chen , Jishun Yang , Liang Xiao , Weibing Dong

High glucose enhances malignant progression of MDA-MB-231 cells through cumulative effect

Published: 27 November 2024 DOI: 10.1016/j.toxlet.2024.11.008
Gaotao Zhang, Zhiqin Liu, Duqiang Luo

New metabolites of 2-ethylhexyl salicylate in human urine after simulated real-life dermal sunscreen application

Published: 20 July 2024 DOI: 10.1016/j.toxlet.2024.07.912
Laura Kuhlmann, Thomas G?en, Julia Hiller

Environmental and occupational exposure to bisphenol compounds in Finland

Published: 7 June 2024 DOI: 10.1016/j.toxlet.2024.06.001
Simo P. Porras, Milla Hein?l?, Henna Veijalainen, Heidi Salo, Katri Suuronen, Evgeny Parshintsev, Tiina Santonen

DPP8/9 inhibition attenuates the TGF-β1-induced excessive deposition of extracellular matrix (ECM) in human mesangial cells via Smad and Akt signaling pathways

Published: 6 March 2024 DOI: 10.1016/j.toxlet.2024.03.001
Ke Li , Yuzhan Zhang , Weihao Zhao , Rongrong Wang , Yan Li , Linting Wei , Li Wang , Xianghui Chen , Zhao Chen , Pengfei Liu , Na Nie , Xuefei Tian , Rongguo Fu

Variable p53/Nrf2 crosstalk contributes to triptolide-induced hepatotoxic process.

Published: 15 April 2023 DOI: 10.1016/j.toxlet.2023.03.011
Zhenyan Hou , Miao Yan , Huixiang Li , Weida Wang , Shen You , Mingjin Wang , Tingting Du , Hui Gong , Wenqun Li , Lin Guo , Shanshan Wei , Bikui Zhang , Ming Ji , Xiaoguang Chen

20-Hydroxytetraenoic acid induces hepatic fibrosis via the TGF-β1/Smad3 signaling pathway

Published: 15 January 2023 DOI: 10.1016/j.toxlet.2022.11.001
Biao Li , Yuchen Ma , Lina Tan , Huan Ren , Lifang Wu , Qian Su , Jue Song , Wei Chen , Peng Gong , Yong Jin

Antimony-induced astrocyte activation via mitogen-activated protein kinase activation-dependent CREB phosphorylation

Published: 1 November 2021 DOI: 10.1016/j.toxlet.2021.09.006
Yudan Zheng , Wenjie Ding , Tao Zhang , Zixuan Zhao , Rui Wang , Zhijie Li , Shali Yu , Jinlong Li , Xinyuan Zhao , Qiyun Wu

Arsenite-induced downregulation of occludin in mouse lungs and BEAS-2B cells via the ROS/ERK/ELK1/MLCK and ROS/p38 MAPK signaling pathways.

Published: 10 October 2020 DOI:
Yingqi Liu , Jing Tang , Jiaming Yuan , Chenjuan Yao , Kazuo Hosoi , Yu Han , Shali Yu , Haiyan Wei , Gang Chen

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Toxicology letters

Oxymatrine antagonises oxidative stress and apoptosis in Nemopilema nomurai toxin-induced cardiotoxicity by inhibiting mitogen-activated protein kinase

High glucose enhances malignant progression of MDA-MB-231 cells through cumulative effect

New metabolites of 2-ethylhexyl salicylate in human urine after simulated real-life dermal sunscreen application

Environmental and occupational exposure to bisphenol compounds in Finland

DPP8/9 inhibition attenuates the TGF-β1-induced excessive deposition of extracellular matrix (ECM) in human mesangial cells via Smad and Akt signaling pathways

Variable p53/Nrf2 crosstalk contributes to triptolide-induced hepatotoxic process.

20-Hydroxytetraenoic acid induces hepatic fibrosis via the TGF-β1/Smad3 signaling pathway

Antimony-induced astrocyte activation via mitogen-activated protein kinase activation-dependent CREB phosphorylation

Arsenite-induced downregulation of occludin in mouse lungs and BEAS-2B cells via the ROS/ERK/ELK1/MLCK and ROS/p38 MAPK signaling pathways.

Keratinocytes apoptosis contributes to crizotinib induced-erythroderma

Enhancing autophagy by down-regulating GSK-3β alleviates cisplatin-induced ototoxicity in vivo and in vitro

Urinary metabolites of the UV filter 2-Ethylhexyl salicylate as biomarkers of exposure in humans

Creatine: are the benefits worth the risk?

The covalent interaction of 1,4-dibromobenzene with rat and mouse nucleic acids: in vivo and in vitro studies