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ChemicalBook >> CAS DataBase List >> N-[4-[5-(1,3-BENZODIOXOL-5-YL)-3-METHOXY-1H-1,2,4-TRIAZOL-1-YL]PHENYL]-2-(PHENYLTHIO)ACETAMIDE

N-[4-[5-(1,3-BENZODIOXOL-5-YL)-3-METHOXY-1H-1,2,4-TRIAZOL-1-YL]PHENYL]-2-(PHENYLTHIO)ACETAMIDE

N-[4-[5-(1,3-BENZODIOXOL-5-YL)-3-METHOXY-1H-1,2,4-TRIAZOL-1-YL]PHENYL]-2-(PHENYLTHIO)ACETAMIDE price.
  • $25 - $1900
  • Product name: N-[4-[5-(1,3-BENZODIOXOL-5-YL)-3-METHOXY-1H-1,2,4-TRIAZOL-1-YL]PHENYL]-2-(PHENYLTHIO)ACETAMIDE
  • CAS: 853625-60-2
  • MF: C24H20N4O4S
  • MW: 460.51
  • EINECS:
  • MDL Number:MFCD10687099
  • Synonyms:N-[4-[5-(1,3-BENZODIOXOL-5-YL)-3-METHOXY-1H-1,2,4-TRIAZOL-1-YL]PHENYL]-2-(PHENYLTHIO)ACETAMIDE;SECINH3;N-(4-(5-(benzo[d][1,3]dioxol-5-yl)-3-methoxy-1H-1,2,4-triazol-1-yl)phenyl)-2-(phenylthio)acetamide;3]dioxol-5-yl)-3-methoxy-1H-1;4-triazol-1-yl)phenyl)-2-(phenylthio)acetamide;N-(4-(5-(benzo[d][1;CS-2379;Acetamide, N-[4-[5-(1,3-benzodioxol-5-yl)-3-methoxy-1H-1,2,4-triazol-1-yl]phenyl]-2-(phenylthio)-
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  • Manufactureraablocks
  • Product numberAA00369F
  • Product descriptionN-[4-[5-(1,3-Benzodioxol-5-yl)-3-methoxy-1H-1,2,4-triazol-1-yl]phenyl]-2-(phenylthio)acetamide 99%
  • Packaging1mg
  • Price$25
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA00369F
  • Product descriptionN-[4-[5-(1,3-Benzodioxol-5-yl)-3-methoxy-1H-1,2,4-triazol-1-yl]phenyl]-2-(phenylthio)acetamide 99%
  • Packaging5mg
  • Price$34
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA00369F
  • Product descriptionN-[4-[5-(1,3-Benzodioxol-5-yl)-3-methoxy-1H-1,2,4-triazol-1-yl]phenyl]-2-(phenylthio)acetamide 99%
  • Packaging10mg
  • Price$65
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA00369F
  • Product descriptionN-[4-[5-(1,3-Benzodioxol-5-yl)-3-methoxy-1H-1,2,4-triazol-1-yl]phenyl]-2-(phenylthio)acetamide 99%
  • Packaging25mg
  • Price$98
  • Updated2026-05-28
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  • ManufacturerACHEMBLOCK
  • Product numberS87314
  • Product descriptionSecinH3 98%
  • Packaging100MG
  • Price$200
  • Updated2026-05-25
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  • ManufacturerACHEMBLOCK
  • Product numberS87314
  • Product descriptionSecinH3 98%
  • Packaging100MG
  • Price$200
  • Updated2026-05-27
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  • ManufacturerACHEMBLOCK
  • Product numberS87314
  • Product descriptionSecinH3 98%
  • Packaging1G
  • Price$995
  • Updated2026-05-25
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  • ManufacturerACHEMBLOCK
  • Product numberS87314
  • Product descriptionSecinH3 98%
  • Packaging1G
  • Price$995
  • Updated2026-05-27
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  • ManufacturerAK Scientific
  • Product number3811CE
  • Product descriptionSecinH3
  • Packaging5mg
  • Price$257
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA923399
  • Product descriptionSecinH3 98+%
  • Packaging25mg
  • Price$124
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA923399
  • Product descriptionSecinH3 98+%
  • Packaging50mg
  • Price$162
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA923399
  • Product descriptionSecinH3 98+%
  • Packaging5mg
  • Price$73
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA923399
  • Product descriptionSecinH3 98+%
  • Packaging10mg
  • Price$95
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberB7207
  • Product descriptionSecinH3
  • Packaging50mg
  • Price$679
  • Updated2026-05-06
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  • ManufacturerApexBio Technology
  • Product numberB7207
  • Product descriptionSecinH3
  • Packaging10mg
  • Price$196
  • Updated2026-05-06
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  • ManufacturerApexBio Technology
  • Product numberB7207
  • Product descriptionSecinH3
  • Packaging25mg
  • Price$378
  • Updated2026-05-06
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Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA00369F N-[4-[5-(1,3-Benzodioxol-5-yl)-3-methoxy-1H-1,2,4-triazol-1-yl]phenyl]-2-(phenylthio)acetamide 99% 1mg $25 2026-05-28 Buy
aablocks AA00369F N-[4-[5-(1,3-Benzodioxol-5-yl)-3-methoxy-1H-1,2,4-triazol-1-yl]phenyl]-2-(phenylthio)acetamide 99% 5mg $34 2026-05-28 Buy
aablocks AA00369F N-[4-[5-(1,3-Benzodioxol-5-yl)-3-methoxy-1H-1,2,4-triazol-1-yl]phenyl]-2-(phenylthio)acetamide 99% 10mg $65 2026-05-28 Buy
aablocks AA00369F N-[4-[5-(1,3-Benzodioxol-5-yl)-3-methoxy-1H-1,2,4-triazol-1-yl]phenyl]-2-(phenylthio)acetamide 99% 25mg $98 2026-05-28 Buy
ACHEMBLOCK S87314 SecinH3 98% 100MG $200 2026-05-25 Buy
ACHEMBLOCK S87314 SecinH3 98% 100MG $200 2026-05-27 Buy
ACHEMBLOCK S87314 SecinH3 98% 1G $995 2026-05-25 Buy
ACHEMBLOCK S87314 SecinH3 98% 1G $995 2026-05-27 Buy
AK Scientific 3811CE SecinH3 5mg $257 2021-12-16 Buy
Ambeed A923399 SecinH3 98+% 25mg $124 2021-12-16 Buy
Ambeed A923399 SecinH3 98+% 50mg $162 2021-12-16 Buy
Ambeed A923399 SecinH3 98+% 5mg $73 2021-12-16 Buy
Ambeed A923399 SecinH3 98+% 10mg $95 2021-12-16 Buy
ApexBio Technology B7207 SecinH3 50mg $679 2026-05-06 Buy
ApexBio Technology B7207 SecinH3 10mg $196 2026-05-06 Buy
ApexBio Technology B7207 SecinH3 25mg $378 2026-05-06 Buy

Properties

storage temp. :Inert atmosphere,2-8°C
solubility :DMF: 30 mg/ml; DMF:PBS (pH 7.2)(1:3): 0.25 mg/ml; DMSO: 25 mg/ml; Ethanol: 0.3 mg/ml
form :White powder solid.
color :White to off-white
InChI :1S/C24H20N4O4S/c1-30-24-26-23(16-7-12-20-21(13-16)32-15-31-20)28(27-24)18-10-8-17(9-11-18)25-22(29)14-33-19-5-3-2-4-6-19/h2-13H,14-15H2,1H3,(H,25,29)
InChIKey :QPGYAMIHXLCFTJ-UHFFFAOYSA-N
SMILES :S(CC(=O)Nc2ccc(cc2)[n]3nc(nc3c4cc5c(cc4)OCO5)OC)c1ccccc1

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

SecinH3 is a cell-permeable triazolo compound that acts as a Sec7 domain-binding (Kd ≤250 nM for Sec7 from human cytohesins 1-3), selective antagonist against cytohesin family small nucleotide exchange factors, or GEFs (IC50 ≤5.6 μM in ARF1 GDP/GTP exchange assays using human cytohesin 3, as well as murine and Drosophila homologues). SecinH3 inhibits large GEFs only at much higher concentrations (IC50 ≥65 μM in GDP/GTP exchange assays using hEFA6-S7 and yGea2-S7) and exhibits little activity against a panel of 10 commonly studied kinases or hSosII. SecinH3 was shown to effectively inhibit insulin signaling both in HepG2 cells in vitro and in Drosophila and mice in vivo. SecinH3 is an inhibitor of cytohesin-1, cytohesin-2 and GRP1.

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