Chk2 Inhibitor
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- $95.8 - $645
- Product name: Chk2 Inhibitor
- CAS: 724708-21-8
- MF: C15H13N5O2
- MW: 295.3
- EINECS:-0
- MDL Number:MFCD22380609
- Synonyms:Chk2 Inhibitor;Chk2 Inhibitor - CAS 724708-21-8 - Calbiochem;Azepino[3,4-b]indol-1(2H)-one, 5-(2-amino-1,5-dihydro-5-oxo-4H-imidazol-4-ylidene)-3,4,5,10-tetrahydro-, (5Z)-;SC 203885;SC203885;SC-203885
9 prices
Selected condition：
Brand
- aablocks
- Cayman Chemical
- Sigma-Aldrich
- TRC
Package
- 500μg
- 1000μg
- 1mg
- 1 unit
- 100 mg
- 500 μg
- Manufactureraablocks
- Product numberAA00FGBC
- Product description(Z)-5-(2-Amino-5-oxo-1H-imidazol-4(5H)-ylidene)-2,3,4,5-tetrahydroazepino[3,4-b]indol-1(10H)-one ≥95%
- Packaging1mg
- Price$426
- Updated2026-05-28
- Buy
- ManufacturerCayman Chemical
- Product number21184
- Product descriptionChk2 Inhibitor
- Packaging1mg
- Price$387
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number21184
- Product descriptionChk2 Inhibitor ≥95%
- Packaging1mg
- Price$426
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number21184
- Product descriptionChk2 Inhibitor
- Packaging500μg
- Price$242
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number21184
- Product descriptionChk2 Inhibitor ≥95%
- Packaging500μg
- Price$267
- Updated2026-04-30
- Buy
- ManufacturerSigma-Aldrich
- Product number220485-M
- Product descriptionChk2 Inhibitor The Chk2 Inhibitor, also referenced under CAS 724708-21-8, controls the biological activity of Chk2. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applic
- Packaging1 unit
- Price$291
- Updated2025-07-31
- Buy
- ManufacturerSigma-Aldrich
- Product number220485-M
- Product descriptionChk2 Inhibitor The Chk2 Inhibitor, also referenced under CAS 724708-21-8, controls the biological activity of Chk2. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applic
- Packaging500 μg
- Price$312
- Updated2026-04-30
- Buy
- ManufacturerSigma-Aldrich
- Product number220485-M
- Product descriptionChk2 Inhibitor The Chk2 Inhibitor, also referenced under CAS 724708-21-8, controls the biological activity of Chk2. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applic
- Packaging100 mg
- Price$95.8
- Updated2025-07-31
- Buy
- ManufacturerTRC
- Product numberC263468
- Product descriptionChk2Inhibitor
- Packaging1000μg
- Price$645
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00FGBC | (Z)-5-(2-Amino-5-oxo-1H-imidazol-4(5H)-ylidene)-2,3,4,5-tetrahydroazepino[3,4-b]indol-1(10H)-one ≥95% | 1mg | $426 | 2026-05-28 | Buy |
| Cayman Chemical | 21184 | Chk2 Inhibitor | 1mg | $387 | 2024-03-01 | Buy |
| Cayman Chemical | 21184 | Chk2 Inhibitor ≥95% | 1mg | $426 | 2026-04-30 | Buy |
| Cayman Chemical | 21184 | Chk2 Inhibitor | 500μg | $242 | 2024-03-01 | Buy |
| Cayman Chemical | 21184 | Chk2 Inhibitor ≥95% | 500μg | $267 | 2026-04-30 | Buy |
| Sigma-Aldrich | 220485-M | Chk2 Inhibitor The Chk2 Inhibitor, also referenced under CAS 724708-21-8, controls the biological activity of Chk2. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applic | 1 unit | $291 | 2025-07-31 | Buy |
| Sigma-Aldrich | 220485-M | Chk2 Inhibitor The Chk2 Inhibitor, also referenced under CAS 724708-21-8, controls the biological activity of Chk2. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applic | 500 μg | $312 | 2026-04-30 | Buy |
| Sigma-Aldrich | 220485-M | Chk2 Inhibitor The Chk2 Inhibitor, also referenced under CAS 724708-21-8, controls the biological activity of Chk2. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applic | 100 mg | $95.8 | 2025-07-31 | Buy |
| TRC | C263468 | Chk2Inhibitor | 1000μg | $645 | 2021-12-16 | Buy |
Properties
storage temp. :-20C
solubility :DMSO: Soluble
form :Pale yellow solid
color :pale yellow
InChIKey :FRROPNANZGODOW-MKFZHGHUSA-N
SMILES :Cl.N1C(=N\C(=C2\CCNC(=O)c3[nH]c4c(c3\2)cccc4)\C1=O)N
solubility :DMSO: Soluble
form :Pale yellow solid
color :pale yellow
InChIKey :FRROPNANZGODOW-MKFZHGHUSA-N
SMILES :Cl.N1C(=N\C(=C2\CCNC(=O)c3[nH]c4c(c3\2)cccc4)\C1=O)N
Safety Information
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Description
Chk2 Inhibitor is an indoloazepine checkpoint kinase inhibitor that mediates apoptosis and cell cycle arrest. Checkpoint kinase 2 is activated upon DNA damage or genomic instability which eventually causes apoptosis. Mechanistic studies show that Chk2 inhibitor causes autophosphorylation of Chk2 at Thr68 and targets ATP binding pockets of Chk2. Further studies demonstrate that Chk2 inhibitors also inhibit Chk1 and MEK-1 and affect interleukin-2 (IL-2), TNF-α, MEK-1, and GSK-3β.More related product prices
Motesanib 371242-69-2 N-[4-[5-(1,3-BENZODIOXOL-5-YL)-3-METHOXY-1H-1,2,4-TRIAZOL-1-YL]PHENYL]-2-(PHENYLTHIO)ACETAMIDE JNJ-10198409 Pictilisib (GDC-0941) GSK-3β Inhibitor XVIII MIF Antagonist, ISO-1 NSC697923 NSC 23766 TETRAHYDROCHLORIDE 53188-07-1 C2 CERAMIDE PD 173074 ERK Inhibitor Compound 23 MMP-9 INHIBITOR I 648926-15-2 Compound 28Related product price
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