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ChemicalBook >> CAS DataBase List >> Indometacin

Indometacin

Indometacin price.
  • $13 - $1700
  • Product name: Indometacin
  • CAS: 53-86-1
  • MF: C19H16ClNO4
  • MW: 357.79
  • EINECS:200-186-5
  • MDL Number:MFCD00057095
  • Synonyms:INDOMETACIN;[1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetic acid;1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1h-indole-3-aceticaci ;1-(4-chlorobenzoyl)-5-methoxy-2-methylindoleaceticacid ;1-(p-chlorbenzoyl)-5-methoxy-2-methylindol-3-essigsaeure ;1-(p-Chlorobenzoyl)-2-methyl-5-methoxy-3-indole-acetic acid;1-(p-chlorobenzoyl)-2-methyl-5-methoxy-3-indole-aceticacid ;1-(p-Chlorobenzoyl)-2-methyl-5-methoxyindole-3-acetic acid
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  • Manufactureraablocks
  • Product numberAA00I9DZ
  • Product description1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-3-indoleacetic acid ≥99%
  • Packaging5g
  • Price$15
  • Updated2026-05-29
  • Buy
  • Manufactureraablocks
  • Product numberAA00I9DZ
  • Product description1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-3-indoleacetic acid ≥99%
  • Packaging25g
  • Price$30
  • Updated2026-05-29
  • Buy
  • Manufactureraablocks
  • Product numberAA00I9DZ
  • Product description1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-3-indoleacetic acid ≥99%
  • Packaging100g
  • Price$71
  • Updated2026-05-29
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  • Manufactureraablocks
  • Product numberAA00I9DZ
  • Product description1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-3-indoleacetic acid ≥99%
  • Packaging500g
  • Price$192
  • Updated2026-05-29
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  • ManufacturerAHH
  • Product numberAPI-1160
  • Product descriptionIndomethacin 98%
  • Packaging1000g
  • Price$310
  • Updated2021-12-16
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  • ManufacturerAHH
  • Product numberAPI-1160
  • Product descriptionIndomethacin 97%
  • Packaging1000g
  • Price$310
  • Updated2026-05-26
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  • ManufacturerAK Scientific
  • Product numberJ52056
  • Product descriptionIndometacin 95%
  • Packaging500gG
  • Price$289
  • Updated2026-06-04
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  • ManufacturerAK Scientific
  • Product numberJ52056
  • Product descriptionIndometacin 95%
  • Packaging100gG
  • Price$95
  • Updated2026-06-04
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  • ManufacturerAK Scientific
  • Product numberJ10170
  • Product descriptionIndometacin 99%(HPLC),powder
  • Packaging100mg
  • Price$99
  • Updated2026-06-04
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  • ManufacturerAK Scientific
  • Product numberH911
  • Product descriptionIndometacin
  • Packaging100g
  • Price$107
  • Updated2021-12-16
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  • ManufacturerAK Scientific
  • Product numberH911
  • Product descriptionIndometacin 98%(HPLC)
  • Packaging100gG
  • Price$133
  • Updated2026-06-04
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  • ManufacturerAK Scientific
  • Product numberJ52056
  • Product descriptionIndometacin
  • Packaging100g
  • Price$80
  • Updated2021-12-16
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  • ManufacturerAK Scientific
  • Product numberJ52056
  • Product descriptionIndometacin 95%
  • Packaging1g
  • Price$13
  • Updated2026-06-04
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  • ManufacturerAK Scientific
  • Product numberJ52056
  • Product descriptionIndometacin
  • Packaging25g
  • Price$30
  • Updated2021-12-16
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  • ManufacturerAK Scientific
  • Product numberH911
  • Product descriptionIndometacin 98%(HPLC)
  • Packaging1g
  • Price$18
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberH911
  • Product descriptionIndometacin
  • Packaging25g
  • Price$41
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA00I9DZ 1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-3-indoleacetic acid ≥99% 5g $15 2026-05-29 Buy
aablocks AA00I9DZ 1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-3-indoleacetic acid ≥99% 25g $30 2026-05-29 Buy
aablocks AA00I9DZ 1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-3-indoleacetic acid ≥99% 100g $71 2026-05-29 Buy
aablocks AA00I9DZ 1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-3-indoleacetic acid ≥99% 500g $192 2026-05-29 Buy
AHH API-1160 Indomethacin 98% 1000g $310 2021-12-16 Buy
AHH API-1160 Indomethacin 97% 1000g $310 2026-05-26 Buy
AK Scientific J52056 Indometacin 95% 500gG $289 2026-06-04 Buy
AK Scientific J52056 Indometacin 95% 100gG $95 2026-06-04 Buy
AK Scientific J10170 Indometacin 99%(HPLC),powder 100mg $99 2026-06-04 Buy
AK Scientific H911 Indometacin 100g $107 2021-12-16 Buy
AK Scientific H911 Indometacin 98%(HPLC) 100gG $133 2026-06-04 Buy
AK Scientific J52056 Indometacin 100g $80 2021-12-16 Buy
AK Scientific J52056 Indometacin 95% 1g $13 2026-06-04 Buy
AK Scientific J52056 Indometacin 25g $30 2021-12-16 Buy
AK Scientific H911 Indometacin 98%(HPLC) 1g $18 2026-06-04 Buy
AK Scientific H911 Indometacin 25g $41 2021-12-16 Buy

Properties

Melting point :158-162 °C
Boiling point :499.4±45.0 °C(Predicted)
Density :1.2135 (rough estimate)
refractive index :1.6800 (estimate)
storage temp. :Store at RT
solubility :ethanol: 50 mg/mL, clear, yellow-green
pka :4.5(at 25℃)
form :White to off-white powder
color :White to Light yellow to Light orange
biological source :synthetic
Water Solubility :Soluble in acetone (40 mg/mL - clear, yellow solution), ethanol (20 mg/mL), ether, castor oil; Soluble in chloroform (50 mg/mL - clear, yellow, extremely viscous solution); decomposed by strong alkali but stable in neutral or slightly acidic media; insoluble in water.
Sensitive :Light Sensitive
Merck :14,4968
BRN :497341
BCS Class :2
Stability :Stable. Incompatible with strong oxidizing agents.
InChI :1S/C19H16ClNO4/c1-11-15(10-18(22)23)16-9-14(25-2)7-8-17(16)21(11)19(24)12-3-5-13(20)6-4-12/h3-9H,10H2,1-2H3,(H,22,23)
InChIKey :CGIGDMFJXJATDK-UHFFFAOYSA-N
SMILES :COc1ccc2n(c(C)c(CC(O)=O)c2c1)C(=O)c3ccc(Cl)cc3
CAS DataBase Reference :53-86-1(CAS DataBase Reference)
NIST Chemistry Reference :Indomethacin(53-86-1)
EPA Substance Registry System :Indomethacin (53-86-1)

Safety Information

Symbol(GHS): Skull and Crossbones (GHS06)
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H300 Fatal if swallowed Acute toxicity,oral Category 1, 2 Danger P264, P270, P301+P310, P321, P330,P405, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

Description

Indomethacin is a non-selective COX inhibitor. The IC50 values for ovine COX-1 and -2 are 0.1 and 6 μM, respectively. The IC50 values for human recombinant COX-1 and -2 are 1.67 and 24.6 μM, respectively.

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