ML 18
|
- $35 - $2400
- Product name: ML 18
- CAS: 1422269-30-4
- MF: C32H35N5O5
- MW: 569.66
- EINECS:-0
- MDL Number:MFCD30182327
- Synonyms:ML 18;BRS-3 antagonist;ML18;ML-18;ML 18;BRS-3 ANTAGONIST;1422269-30-4;ML18, >98%;(2S)-3-(1H-INDOL-3-YL)-N-{[1-(4-METHOXYPHENYL)CYCLOHEXYL]METHYL}-2-{[(4-NITROPHENYL)CARBAMOYL]AMINO}PROPANAMIDE;(S)-3-(1H-Indol-3-yl)-N-((1-(4-methoxyphenyl)cyclohexyl)methyl)-2-(3-(4-nitrophenyl)ureido)propanamide;Bombesin Receptor,ML-18,ML 18,inhibit,Inhibitor,ML18;ML-18, 10 mM in DMSO
55 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- Ambeed
- Arctom
- Cayman Chemical
- ChemScene
- CSNpharm
- DC Chemicals
- TRC
- Usbiological
Package
- 10mM*1mLinDMSO(Solution)
- 10mM*1mLinDMSO(Solid+Solvent)
- 500μg
- 1mg
- 2mg
- 2.5mg
- 10mM*1mLinDMSO
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 200mg
- 250mg
- 1G
- Manufactureraablocks
- Product numberAA01DU71
- Product descriptionML-18 98
- Packaging1mg
- Price$44
- Updated2026-05-29
- Buy
- Manufactureraablocks
- Product numberAA01DU71
- Product descriptionML-18 98%
- Packaging2mg
- Price$46
- Updated2026-05-29
- Buy
- Manufactureraablocks
- Product numberAA01DU71
- Product descriptionML-18 98%
- Packaging5mg
- Price$56
- Updated2026-05-29
- Buy
- Manufactureraablocks
- Product numberAA01DU71
- Product descriptionML-18 98%
- Packaging10mg
- Price$89
- Updated2026-05-29
- Buy
- Manufactureraablocks
- Product numberAA01DU71
- Product descriptionML-18 98
- Packaging200mg
- Price$543
- Updated2026-05-29
- Buy
- Manufactureraablocks
- Product numberAA01DU71
- Product descriptionML-18 98
- Packaging100mg
- Price$399
- Updated2026-05-29
- Buy
- Manufactureraablocks
- Product numberAA01DU71
- Product descriptionML-18 98
- Packaging50mg
- Price$255
- Updated2026-05-29
- Buy
- Manufactureraablocks
- Product numberAA01DU71
- Product descriptionML-18 98
- Packaging25mg
- Price$171
- Updated2026-05-29
- Buy
- ManufacturerACHEMBLOCK
- Product numberO33778
- Product descriptionML 18 98%
- Packaging100MG
- Price$235
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberO33778
- Product descriptionML 18 98%
- Packaging1G
- Price$1395
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberO33778
- Product descriptionML 18 98%
- Packaging25MG
- Price$90
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product number3037EC
- Product description(2S)-3-(1H-Indol-3-yl)-N-[[1-(4-methoxyphenyl)cyclohexyl]methyl]-2-[(4-nitrophenyl)carbamoylamino]propanamide
- Packaging5mg
- Price$134
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA708758
- Product descriptionML-18 98%
- Packaging10mg
- Price$151
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA708758
- Product descriptionML-18 98%
- Packaging25mg
- Price$197
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA708758
- Product descriptionML-18 98%
- Packaging5mg
- Price$116
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA708758
- Product descriptionML-18 98%
- Packaging50mg
- Price$257
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA01DU71 | ML-18 98 | 1mg | $44 | 2026-05-29 | Buy |
| aablocks | AA01DU71 | ML-18 98% | 2mg | $46 | 2026-05-29 | Buy |
| aablocks | AA01DU71 | ML-18 98% | 5mg | $56 | 2026-05-29 | Buy |
| aablocks | AA01DU71 | ML-18 98% | 10mg | $89 | 2026-05-29 | Buy |
| aablocks | AA01DU71 | ML-18 98 | 200mg | $543 | 2026-05-29 | Buy |
| aablocks | AA01DU71 | ML-18 98 | 100mg | $399 | 2026-05-29 | Buy |
| aablocks | AA01DU71 | ML-18 98 | 50mg | $255 | 2026-05-29 | Buy |
| aablocks | AA01DU71 | ML-18 98 | 25mg | $171 | 2026-05-29 | Buy |
| ACHEMBLOCK | O33778 | ML 18 98% | 100MG | $235 | 2026-05-27 | Buy |
| ACHEMBLOCK | O33778 | ML 18 98% | 1G | $1395 | 2026-05-27 | Buy |
| ACHEMBLOCK | O33778 | ML 18 98% | 25MG | $90 | 2026-05-27 | Buy |
| AK Scientific | 3037EC | (2S)-3-(1H-Indol-3-yl)-N-[[1-(4-methoxyphenyl)cyclohexyl]methyl]-2-[(4-nitrophenyl)carbamoylamino]propanamide | 5mg | $134 | 2021-12-16 | Buy |
| Ambeed | A708758 | ML-18 98% | 10mg | $151 | 2021-12-16 | Buy |
| Ambeed | A708758 | ML-18 98% | 25mg | $197 | 2021-12-16 | Buy |
| Ambeed | A708758 | ML-18 98% | 5mg | $116 | 2021-12-16 | Buy |
| Ambeed | A708758 | ML-18 98% | 50mg | $257 | 2021-12-16 | Buy |
Properties
Boiling point :821.8±65.0 °C(Predicted)
Density :1.291±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble
form :A solid
pka :11.99±0.46(Predicted)
color :White to yellow
Density :1.291±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble
form :A solid
pka :11.99±0.46(Predicted)
color :White to yellow
Safety Information
| Symbol(GHS): |
|
|||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Signal word: | Warning | |||||||||||||||||||||||||||||||||||
| Hazard statements: |
|
|||||||||||||||||||||||||||||||||||
| Precautionary statements: |
|
Description
ML-18 is a non-peptide bombesin receptor subtype 3 (BB3) antagonist that inhibits [125I]BA1 binding to NCI-H1299 lung cancer cells transfected with human BB3 receptors (IC50 = 4.8 μM). It is selective for BB3 over the gastrin releasing peptide receptor (GRPR) and the neuromedin B receptor (NMBR) with IC50 values of 16 and >100 μM, respectively, in a radioligand binding assay. ML-18 (16 μM) reversibly inhibits BA1-induced increases in cytosolic calcium in NCI-H1299 cells. It also inhibits BA1-induced phosphorylation of ERK and EGFR and reduces proliferation of NCI-H1299 cells.Related product price
-
ML264
$22-1700 -
ML213
$8-2580 -
1360705-96-9
$32-3791
