Midostaurin
|
- $22 - $3494
- Product name: Midostaurin
- CAS: 120685-11-2
- MF: C35H30N4O4
- MW: 570.64
- EINECS:999-999-2
- MDL Number:MFCD10687105
- Synonyms:CGP 41251MIDOSTAURIN(PKC412);N-((5S,6R,7R,9R)-6-Methoxy-14-oxo-5,6,7,8,9,14,15,16-octahydro-17-oxa-4b,9a,15-triaza-5,9-Methanodibenzo[b,h]cyclonona[jkl]cyclopenta[e]-as-indacen-7-yl)-N-MethylbenzaMide;PKC-412, CGP-41251;Midostaurin (PKC412);PKC412 (Midostaurin);CGP 41231;(Midostaurin) Benzoylstaurosporine;midostaruin
90 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- Ambeed
- ApexBio Technology
- Apolloscientific
- Arctom
- AvaChem
- Biosynth
- Cayman Chemical
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
- Medical Isotopes, Inc.
- Sigma-Aldrich
- Thermo Scientific Chemicals
- TRC
- Usbiological
Package
- 1mg
- 5MG
- 10mg
- 25MG
- 10mM*1mLinDMSO
- 50mg
- 100mg
- 250mg
- 1g
- Manufactureraablocks
- Product numberAA00383L
- Product descriptionN-Benzoylstaurosporine ≥99%
- Packaging50mg
- Price$31
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00383L
- Product descriptionN-Benzoylstaurosporine 99%
- Packaging100mg
- Price$58
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00383L
- Product descriptionN-Benzoylstaurosporine 99%
- Packaging250mg
- Price$100
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00383L
- Product descriptionN-Benzoylstaurosporine 99%
- Packaging1g
- Price$278
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberM22540
- Product descriptionPKC412 98%
- Packaging100MG
- Price$280
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product numberM22540
- Product descriptionPKC412 98%
- Packaging100MG
- Price$280
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberM22540
- Product descriptionPKC412 98%
- Packaging25MG
- Price$95
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product numberM22540
- Product descriptionPKC412 98%
- Packaging25MG
- Price$95
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberM22540
- Product descriptionPKC412 98%
- Packaging5MG
- Price$35
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product numberM22540
- Product descriptionPKC412 98%
- Packaging5MG
- Price$35
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberM22540
- Product descriptionPKC412 98%
- Packaging1G
- Price$1450
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product numberM22540
- Product descriptionPKC412 98%
- Packaging1G
- Price$1450
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product number3850AH
- Product descriptionMidostaurin hydrate
- Packaging50mg
- Price$651
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA297057
- Product descriptionPKC412 99%
- Packaging100mg
- Price$275
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA297057
- Product descriptionPKC412 99%
- Packaging1mg
- Price$22
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA297057
- Product descriptionPKC412 99%
- Packaging5mg
- Price$51
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00383L | N-Benzoylstaurosporine ≥99% | 50mg | $31 | 2026-05-28 | Buy |
| aablocks | AA00383L | N-Benzoylstaurosporine 99% | 100mg | $58 | 2026-05-28 | Buy |
| aablocks | AA00383L | N-Benzoylstaurosporine 99% | 250mg | $100 | 2026-05-28 | Buy |
| aablocks | AA00383L | N-Benzoylstaurosporine 99% | 1g | $278 | 2026-05-28 | Buy |
| ACHEMBLOCK | M22540 | PKC412 98% | 100MG | $280 | 2026-05-25 | Buy |
| ACHEMBLOCK | M22540 | PKC412 98% | 100MG | $280 | 2026-05-27 | Buy |
| ACHEMBLOCK | M22540 | PKC412 98% | 25MG | $95 | 2026-05-25 | Buy |
| ACHEMBLOCK | M22540 | PKC412 98% | 25MG | $95 | 2026-05-27 | Buy |
| ACHEMBLOCK | M22540 | PKC412 98% | 5MG | $35 | 2026-05-25 | Buy |
| ACHEMBLOCK | M22540 | PKC412 98% | 5MG | $35 | 2026-05-27 | Buy |
| ACHEMBLOCK | M22540 | PKC412 98% | 1G | $1450 | 2026-05-25 | Buy |
| ACHEMBLOCK | M22540 | PKC412 98% | 1G | $1450 | 2026-05-27 | Buy |
| AK Scientific | 3850AH | Midostaurin hydrate | 50mg | $651 | 2021-12-16 | Buy |
| Ambeed | A297057 | PKC412 99% | 100mg | $275 | 2021-12-16 | Buy |
| Ambeed | A297057 | PKC412 99% | 1mg | $22 | 2021-12-16 | Buy |
| Ambeed | A297057 | PKC412 99% | 5mg | $51 | 2021-12-16 | Buy |
Properties
Melting point :235-260℃
Density :1.47±0.1 g/cm3(Predicted)
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :Soluble in DMSO (15 mg/ml), MDC (10 mg/ml), methanol (5 mg/ml), 100% ethanol (2.5 mg/ml), and DMF (20 mg/ml).
pka :14.19±0.70(Predicted)
form :Tan solid
color :White
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.
InChIKey :BMGQWWVMWDBQGC-QIZZVXHTNA-N
SMILES :C(N([C@@H]1C[C@@]2([H])O[C@@](C)([C@@H]1OC)N1C3=C(C4=C1C1=C(C5=C(N21)C=CC=C5)C1C(=O)NCC=14)C=CC=C3)C)(=O)C1=CC=CC=C1 |&1:2,4,7,9,r|
Density :1.47±0.1 g/cm3(Predicted)
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :Soluble in DMSO (15 mg/ml), MDC (10 mg/ml), methanol (5 mg/ml), 100% ethanol (2.5 mg/ml), and DMF (20 mg/ml).
pka :14.19±0.70(Predicted)
form :Tan solid
color :White
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.
InChIKey :BMGQWWVMWDBQGC-QIZZVXHTNA-N
SMILES :C(N([C@@H]1C[C@@]2([H])O[C@@](C)([C@@H]1OC)N1C3=C(C4=C1C1=C(C5=C(N21)C=CC=C5)C1C(=O)NCC=14)C=CC=C3)C)(=O)C1=CC=CC=C1 |&1:2,4,7,9,r|
Safety Information
| Symbol(GHS): |
|
||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Signal word: | Danger | ||||||||||||
| Hazard statements: |
|
||||||||||||
| Precautionary statements: |
|
Description
PKC 412 is a cell-permeable, reversible inhibitor of several serine/threonine and tyrosine kinases, including conventional PKC isoforms (α, β, and γ), Syk, FLK1, Akt, PKA, c-Kit, C-Fgr, c-Src, FLT3, PDFRβ, VEGFR1, and VEGFR2 with IC50 values ranging from 80-500 nM. It also upregulates the expression of endothelial nitric oxide synthase (eNOS) in mice. PKC 412 inhibits growth or induces apoptosis in many cancer cell types, blocks angiogenesis in tumors, and sensitizes cancer cells to ionizing radiation, supporting its use in cancer therapy.Related product price
-
Ibrutinib
$5-1360 -
189453-10-9
$55-2600 -
ZM 447439
$24-2839
Suppliers and manufacturers
shandong perfect biotechnology co.ltd
Midostaurin
CAS:120685-11-2
Hangzhou ICH Biofarm Co., Ltd
Midostaurin
CAS:120685-11-2
Shaanxi Haibo Biotechnology Co., Ltd
Midostaurin
CAS:120685-11-2
Wuhan JiyunZen Tech Co., Ltd.
Midostaurin
CAS:120685-11-2
Chongqing Qiantai Pharma Co., Ltd.
ATK CHEMICAL COMPANY LIMITED
Biochempartner
TopScience Biochemical
Midostaurin
CAS:120685-11-2
