NS 1619
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- $10 - $3176
- Product name: NS 1619
- CAS: 153587-01-0
- MF: C15H8F6N2O2
- MW: 362.23
- EINECS:
- MDL Number:MFCD00928190
- Synonyms:NS 1619;NS 1619 (1,3-DIHYDRO-1-(2-HYDROXY-5-(TRI FLUOROMETHYL)PHEN;1,3-DIHYDRO-1-[2-HYDROXY-5-(TRIFLUOROMETHYL)PHENYL]-5-(TRIFLUOROMETHYL)-2H-BENZIMIDAZOL-2-ONE;1-(2-hydroxy-5-(trifluoroMethyl)phenyl)-5-(trifluoroMethyl)-1H-b;NS1619;NS 1619;NS 161;2H-Benzimidazol-2-one, 1,3-dihydro-1-[2-hydroxy-5-(trifluoromethyl)phenyl]-5-(trifluoromethyl)-;1-[2-Hydroxy-5-(trifluoromethyl)phenyl]-5-(trifluoromethyl)-1,3-dihydro-2H-benzimidazol-2-one
51 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AHH
- AK Scientific
- Ambeed
- ApexBio Technology
- AvaChem
- Axon Medchem
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
- Sigma-Aldrich
- Synthonix
- TCI Chemical
- Tocris
- TRC
- Usbiological
Package
- 10
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 0.05g
- 100.00mg
- 100mg
- 250.00mg
- 250MG
- 1G
- 1.00g
- Manufactureraablocks
- Product numberAA003CRU
- Product descriptionNS-1619 98%
- Packaging1mg
- Price$10
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA003CRU
- Product descriptionNS-1619 98%
- Packaging5mg
- Price$16
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA003CRU
- Product descriptionNS-1619 98%
- Packaging10mg
- Price$22
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA003CRU
- Product descriptionNS-1619 ≥98%
- Packaging100mg
- Price$120
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberP50910
- Product descriptionNS1619 98%
- Packaging100MG
- Price$130
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberP50910
- Product descriptionNS1619 98%
- Packaging250MG
- Price$225
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberP50910
- Product descriptionNS1619 98%
- Packaging1G
- Price$665
- Updated2026-05-27
- Buy
- ManufacturerAHH
- Product numberMT-20299
- Product descriptionNS 1619 98%
- Packaging0.05g
- Price$368
- Updated2021-12-16
- Buy
- ManufacturerAHH
- Product numberMT-20299
- Product descriptionNS-1619 97%
- Packaging0.05g
- Price$368
- Updated2026-05-25
- Buy
- ManufacturerAHH
- Product numberMT-20299
- Product descriptionNS-1619 97%
- Packaging0.05g
- Price$368
- Updated2026-05-26
- Buy
- ManufacturerAK Scientific
- Product numberX6428
- Product description1-(2-Hydroxy-5-(trifluoromethyl)phenyl)-5-(trifluoromethyl)-1H-benzo[d]imidazol-2(3H)-one
- Packaging5mg
- Price$136
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA900983
- Product descriptionNS 1619 98+%
- Packaging250mg
- Price$238
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA900983
- Product descriptionNS 1619 98+%
- Packaging10mg
- Price$33
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA900983
- Product descriptionNS 1619 98+%
- Packaging1mg
- Price$10
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7502
- Product descriptionNS 1619
- Packaging10mg
- Price$108
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7502
- Product descriptionNS 1619
- Packaging10mg
- Price$108
- Updated2026-05-06
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA003CRU | NS-1619 98% | 1mg | $10 | 2026-05-28 | Buy |
| aablocks | AA003CRU | NS-1619 98% | 5mg | $16 | 2026-05-28 | Buy |
| aablocks | AA003CRU | NS-1619 98% | 10mg | $22 | 2026-05-28 | Buy |
| aablocks | AA003CRU | NS-1619 ≥98% | 100mg | $120 | 2026-05-28 | Buy |
| ACHEMBLOCK | P50910 | NS1619 98% | 100MG | $130 | 2026-05-27 | Buy |
| ACHEMBLOCK | P50910 | NS1619 98% | 250MG | $225 | 2026-05-27 | Buy |
| ACHEMBLOCK | P50910 | NS1619 98% | 1G | $665 | 2026-05-27 | Buy |
| AHH | MT-20299 | NS 1619 98% | 0.05g | $368 | 2021-12-16 | Buy |
| AHH | MT-20299 | NS-1619 97% | 0.05g | $368 | 2026-05-25 | Buy |
| AHH | MT-20299 | NS-1619 97% | 0.05g | $368 | 2026-05-26 | Buy |
| AK Scientific | X6428 | 1-(2-Hydroxy-5-(trifluoromethyl)phenyl)-5-(trifluoromethyl)-1H-benzo[d]imidazol-2(3H)-one | 5mg | $136 | 2021-12-16 | Buy |
| Ambeed | A900983 | NS 1619 98+% | 250mg | $238 | 2021-12-16 | Buy |
| Ambeed | A900983 | NS 1619 98+% | 10mg | $33 | 2021-12-16 | Buy |
| Ambeed | A900983 | NS 1619 98+% | 1mg | $10 | 2021-12-16 | Buy |
| ApexBio Technology | B7502 | NS 1619 | 10mg | $108 | 2021-12-16 | Buy |
| ApexBio Technology | B7502 | NS 1619 | 10mg | $108 | 2026-05-06 | Buy |
Properties
Density :1.563±0.06 g/cm3(Predicted)
storage temp. :Inert atmosphere,2-8°C
solubility :45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 0.47 mg/mL
pka :8.32±0.48(Predicted)
form :solid
color :white
Water Solubility :45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 0.47mg/mL
ethanol: 26.6mg/mL
0.1 M NaOH: 5.2mg/mL
DMSO: 5.3mg/mL
H2O: insoluble InChI :InChI=1S/C15H8F6N2O2/c16-14(17,18)7-1-3-10-9(5-7)22-13(25)23(10)11-6-8(15(19,20)21)2-4-12(11)24/h1-6,24H,(H,22,25)
InChIKey :YLFMCMWKHSDUCT-UHFFFAOYSA-N
SMILES :C1(=O)N(C2=CC(C(F)(F)F)=CC=C2O)C2=CC=C(C(F)(F)F)C=C2N1
storage temp. :Inert atmosphere,2-8°C
solubility :45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 0.47 mg/mL
pka :8.32±0.48(Predicted)
form :solid
color :white
Water Solubility :45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 0.47mg/mL
ethanol: 26.6mg/mL
0.1 M NaOH: 5.2mg/mL
DMSO: 5.3mg/mL
H2O: insoluble InChI :InChI=1S/C15H8F6N2O2/c16-14(17,18)7-1-3-10-9(5-7)22-13(25)23(10)11-6-8(15(19,20)21)2-4-12(11)24/h1-6,24H,(H,22,25)
InChIKey :YLFMCMWKHSDUCT-UHFFFAOYSA-N
SMILES :C1(=O)N(C2=CC(C(F)(F)F)=CC=C2O)C2=CC=C(C(F)(F)F)C=C2N1
Safety Information
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Description
NS 1619 is a calcium-dependent activator of large-conductance Ca2+-activated K+ (BKCa) channels in vascular smooth muscle. It is typically used at a concentration of 30 μM to hyperpolarize the membrane potential of single myocytes during studies of smooth muscle relaxation and vasodilation. Studies suggest that activation of BKCa channels by NS 1619 can protect the cardiac muscle against pulmonary hypertension as well as ischemia and reperfusion injury in various animal models.Related product price
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