1-Octanol synthesis
- Product Name:1-Octanol
- CAS Number:111-87-5
- Molecular formula:C8H18O
- Molecular Weight:130.23
111-11-5
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111-87-5
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$6.00/100g
Yield:111-87-5 99%
Reaction Conditions:
with C32H36ClNO2P2Ru;potassium tert-butylate;hydrogen in neat (no solvent) at 120; under 38002.6 Torr; for 20 h;Autoclave;Green chemistry;
Steps:
52; 72 Example 72: Hydrogenation of methyl octanoate catalyzed by one-tenth molar equivalent of ruthenium complex 1c under solvent-free conditions
In a glove box in a nitrogen atmosphere, 0.67 mg of ruthenium complex 1c (0.001 mmol) Add to a 125-mL Parr autoclave, After adding 11.2 mg of potassium t-butoxide (0.1 mmol), Methyl octanoate (1.5824 g, 10 mmol) was added. After the autoclave is sealed, it is taken out of the glove box. Charge hydrogen to 50 atm. The mixture in the reaction kettle was heated and stirred in an oil bath at 120 ° C for 20 hours, The reactor was cooled to room temperature in a water bath. Slowly drain the remaining gas in the fume hood. Sampling nuclear magnetic observation directly from the kettle, The display has completely reacted completely, The mixture was filtered through a short silica gel column (about 2 cm). The filtrate obtained after washing with ethyl acetate (5 mL x 3), The solvent was removed by rotary evaporation to give hexanol (1.273 g). The yield was 99%.
References:
CN109553641,2019,A Location in patent:Paragraph 0422-0425; 0503-0506
![Benzene, 1-methoxy-4-[(octyloxy)methyl]-](/CAS/20210305/GIF/54384-75-7.gif)
54384-75-7
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111-87-5
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106-32-1
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111-87-5
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124-13-0
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111-87-5
798 suppliers
$6.00/100g