N- (4- chloro- 3- methyl- oxazol- 5- yl)- 2- [2- (6- methylbenzo[1,3]dioxol- 5- yl)acetyl]- thiophene- 3- sulfonamide synthesis
- Product Name:N- (4- chloro- 3- methyl- oxazol- 5- yl)- 2- [2- (6- methylbenzo[1,3]dioxol- 5- yl)acetyl]- thiophene- 3- sulfonamide
- CAS Number:184036-34-8
- Molecular formula:C18H15ClN2O6S2
- Molecular Weight:454.9
117661-72-0
51 suppliers
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184036-34-8
56 suppliers
$286.00/10mg
Yield:184036-34-8 71%
Steps:
6 N-(4-chloro-3-methyl-5-isoxazolyl)-2-[3,4-(methylenedioxy)-6-methyl]phenyl-acetyl-3-thiophenesulfonamide also designated 4-chloro-3-methyl-5-(2-(2-(6-methylbenzo[d][1,3]dioxol-5-yl)acetyl)-3-thienylsulfonamido)isoxazole and N-(4-chloro-3-methyl-5-isoxazolyl)-2-[2-methyl-4,5-(methylenedioxy)phenylacetyl]thiophene-3-sulfonamide
N-(4-chloro-3-methyl-5-isoxazolyl)-2-[3,4-(methylenedioxy)-6-methyl]phenylacetyl-3-thiophenesulfonamide was synthesised in the same manner as for Example 5 using (3,4-methylenedioxy)-6-methylbenzyl chloride instead of (3,4-methylenedioxy)benzyl chloride. The crude product was purified by preparative HPLC to give N-(4-chloro-3-methyl-5-isoxazolyl)-2-[3,4-(methylenedioxy)-6-methyl]phenylacetyl-3-thiophenesulfonamide as a yellow powder (71% yield, m.p. 42-45° C.).
References:
US2002/91270,2002,A1
1008726-80-4
1 suppliers
inquiry
210421-71-9
20 suppliers
$505.38/5MG
184036-34-8
56 suppliers
$286.00/10mg
117661-72-0
51 suppliers
inquiry
210421-71-9
20 suppliers
$505.38/5MG
184036-34-8
56 suppliers
$286.00/10mg
20850-43-5
166 suppliers
$17.67/1gm:
117661-72-0
51 suppliers
inquiry
210421-71-9
20 suppliers
$505.38/5MG
184036-34-8
56 suppliers
$286.00/10mg
210421-71-9
20 suppliers
$505.38/5MG
184036-34-8
56 suppliers
$286.00/10mg