ChemicalBook CAS DataBase List 2,4-Dichlorotoluene

2,4-Dichlorotoluene synthesis

12synthesis methods

Product Name:2,4-Dichlorotoluene
CAS Number:95-73-8
Molecular formula:C7H6Cl2
Molecular Weight:161.03

2,4-Dichlorotoluene is synthesized by diazotization and chlorination with 2,4-diaminotoluene as raw material. First, hydrochloric acid and water into the reaction pot, heated to 50°C, stirring under the dissolution of 2,4-diaminotoluene, then hydrochloric acid and cuprous chloride into the pot, the 1% sodium nitrite solution evenly added, the temperature is maintained at about 60°C, resting stratification, the lower layer of crude product washed with water to neutral, add alkali to alkaline, and then water to remove the alkali, divided 2,4-dichlorotoluene crude product, water distillation of finished products.

95-80-7 Synthesis

95-80-7
267 suppliers
$12.00/1mg

95-73-8
260 suppliers
$14.00/5g

Yield:95-73-8 85%

Reaction Conditions:

with potassium bisulfite;potassium chloride;cobalt(II) chloride in water at 70 - 75; for 2.33333 h;Concentration;Temperature;

Steps:

3 Example 3:
(I) in the is provided with a stirrer, thermometer, dropping funnel in the reaction container, adding the mass fraction of 70% potassium chloride solution 2000 ml, 1 . 2mol of the 2,4-diamino-toluene (2), 0.7mol asian cobalt chloride, stirring after mixing, stirring speed-keeping 300rpm, control the temperature of the solution heated up to 75 °C, potassium sulfite dropping 2.6mol soluble in water to form a solution, potassium sulfite control the time of process solution 1.5h, the sulfurous acid potassium in solution are added to a reaction vessel, to control the reaction temperature of the solution 70 °C, keeping the temperature of the solution after adding 75 °C, duration 50 min, the temperature of the solution is then reduced to 32 °C, drop the oil reservoir, the solvent is washed with methanol, sodium carbonate solution, water vapor 1.7kPa low-pressure distillation, from the oil reservoir in the distillate, shall be 2,4-dichloro-toluene 164.22g, yield 85%.

References:

Chengdu Science and Technology Co., Ltd.;Peng, Xiangliang CN105439809, 2016, A Location in patent:Paragraph 0015; 0016

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