2-Bromoethylamine hydrobromide synthesis
- Product Name:2-Bromoethylamine hydrobromide
- CAS Number:2576-47-8
- Molecular formula:C2H7Br2N
- Molecular Weight:204.89
141-43-5
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2576-47-8
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Yield:2576-47-8 99%
Reaction Conditions:
with hydrogen bromide in 5,5-dimethyl-1,3-cyclohexadiene at 0 - 10; for 12 h;
Steps:
1 (1) Synthesis of 2-bromoethylamine hydrobromide (b)
Ethanolamine was added dropwise to 40% hydrobromic acid at a molar ratio of 1:9 at 0-10 ° C, magnetically stirred, the temperature of the reaction system was controlled to not exceed 10 ° C, and the time of dropwise addition of ethanolamine was controlled at 25-30 min. After the addition is completed, it is transferred to the reaction system. The solvent xylene was added, and the water was separated by heating for 12 hours, and the water separation temperature was 135-145 °C. After completion of the water separation, the mixture was cooled, filtered to remove the solvent, and the residue was washed three times with cold acetone to obtain a white crystalline product of 2-bromoethylamine hydrobromide. Yield 99%, purity 99.5%, Melting point 172-174 ° C
References:
Chongqing Normal University;Chongqing Traditional Chinese Medicine Institute;Yang Shanbin;Zhou Shiyang;Yang Dajian CN108658852, 2018, A Location in patent:Paragraph 0024; 0025-0026
574-98-1
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2576-47-8
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2576-47-8
492 suppliers
$8.00/25g