3,5-DIFLUOROBENZAMIDE synthesis
- Product Name:3,5-DIFLUOROBENZAMIDE
- CAS Number:132980-99-5
- Molecular formula:C7H5F2NO
- Molecular Weight:157.12
64248-63-1
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$6.00/5g
132980-99-5
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$19.00/5g
Yield: 100%
Reaction Conditions:
with [{Au(IPr)}2(μ-OH)][BF4];water in tetrahydrofuran at 140; under 5250.53 Torr; for 2 h;Sealed tube;Microwave irradiation;Reagent/catalyst;
Steps:
A Hydration of Nitriles
In a typical reaction, [Au(IPr)(NTf2)] (13 mg, 20 μmol, 2 mol %) or [{Au(IPr)}2(μ-OH)]BF4 (17 mg, 10 μmol, 1 mol %) was added to THF (0.5 mL) in a 2 mL microwave vial in air. Benzonitrile (103 mg, 1 mmol) was added, followed by distilled H2O (500 μL). The vial was sealed and heated in the microwave for 2 h at 140° C. (7 bar). The conversion was determined by gas chromatography
References:
University Court of The University of St. Andrews;Nolan, Steven P. US2013/35322, 2013, A1 Location in patent:Paragraph 0112
32085-88-4
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132980-99-5
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129714-97-2
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132980-99-5
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455-40-3
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132980-99-5
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$19.00/5g